| B.F. Francis Ouellette | |
|---|---|
|   Ouellette in 2025 | |
| Born | June 3, 1960 Quebec City, Québec, Canada | 
| Alma mater | McGill University, University of Calgary | 
| Known for | Bioinformatics training in Canada, Open Science advocacy, GenBank coordination, ISCB leadership | 
| Children | 2 | 
| Scientific career | |
| Fields | Bioinformatics, Genomics, Computational Biology | 
| Institutions | McGill University, National Center for Biotechnology Information/NLM/NIH, University of British Columbia, Ontario Institute for Cancer Research, Genome Québec. | 
B.F. Francis Ouellette (born 3 June 1960) is a Canadian bioinformatician. His work has focused on genome annotation, data resources for molecular biology, and training in bioinformatics. He has held research and administrative positions in Canada and the United States and serves on several editorial and scientific advisory boards.
Ouellette began his career at McGill University in the early 1990s, coordinating the sequencing of Saccharomyces cerevisiae chromosome I. From 1993 to 1998 he worked at the National Center for Biotechnology Information (NCBI) at the NIH as the GenBank coordinator, overseeing sequence submissions and contributing to databases such as dbEST and RefSeq.
From 1998 to 2007 he held positions at the University of British Columbia, including director of the CMMT Bioinformatics Core and of the UBC Bioinformatics Centre (UBiC). He was also associate professor in the Department of Medical Genetics and the Michael Smith Laboratory, and helped develop one of Canada's first graduate programs in bioinformatics with colleagues at UBC and SFU.
Between 2007 and 2017 Ouellette was associate director of informatics and biocomputing at the Ontario Institute for Cancer Research (OICR), where he led data‑management and software projects associated with the ICGC. He later served as chief scientific officer at Genome Québec (2017–2018) and executive director of the Neuro Bioinformatics Core Facility at the Montréal Neurological Institute (2021–2022).
As of 2025 he works as an independent consultant and participates in editorial and advisory activities.
Ouellette's research has addressed genome annotation, protein–protein interaction databases, and transcriptomics. He co‑authored more than 80 publications and was a co‑lead on the Biomolecular Interaction Network Database (BIND).
He co‑edited Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins with Andreas Baxevanis, published in three editions by Wiley between 1998 and 2005. [1]
He also directed the Canadian Bioinformatics Workshops program (bioinformatics.ca), which offered short courses and training events in bioinformatics from 1999 to 2021.