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Coronary thrombosis is defined as the formation of a blood clot inside a blood vessel of the heart. This blood clot may then restrict blood flow within the heart, leading to heart tissue damage, or a myocardial infarction, also known as a heart attack.
Acute coronary syndrome (ACS) is a syndrome due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function properly or dies. The most common symptom is centrally located pressure-like chest pain, often radiating to the left shoulder or angle of the jaw, and associated with nausea and sweating. Many people with acute coronary syndromes present with symptoms other than chest pain, particularly women, older people, and people with diabetes mellitus.
Paul M. Ridker is a cardiovascular epidemiologist and biomedical researcher. He is currently the Eugene Braunwald Professor of Medicine at Harvard University and Brigham and Women's Hospital, where he directs the Center for Cardiovascular Disease Prevention. Ridker also holds an appointment as Professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health.
Désiré, Baron Collen is a Belgian physician, chemist, biotechnology entrepreneur and life science investor. He made several discoveries in thrombosis, haemostasis and vascular biology in many of which serendipity played a significant role. His main achievement has been his role in the development of tissue-type plasminogen activator (t-PA) from a laboratory concept to a life-saving drug for dissolving blood clots causing acute myocardial infarction or acute ischemic stroke. Recombinant t-PA was produced and marketed by Genentech Inc as Activase and by Boehringer Ingelheim GmbH as Actilyse, and is considered biotechnology's first life saving drug.
Marc Van Ranst is a Belgian public health doctor and Professor of Virology at the Katholieke Universiteit Leuven and the Rega Institute for Medical Research. On 1 May 2007, he was appointed as Interministerial comissionar by the Belgian federal government to prepare Belgium for an influenza pandemic.
Franciscus (Frans) Vanistendael (1942-2021) was a Belgian expert on tax law and former professor at the Katholieke Universiteit Leuven (KUL) and the Brussels Tax College (HUBrussel). Until 2005 he was dean of the law school of the KU Leuven. He was a member of the Coudenberg group, a Belgian federalist think tank. Frans Vanistendael is a brother of the writer Geert van Istendael.
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A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw. Often it occurs in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, feeling tired, and decreased level of consciousness. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, cardiogenic shock or cardiac arrest.
Mark Jozef Albert, Baron Waer is a Belgian physician, biomedical scientist, and former Rector of the Katholieke Universiteit Leuven.
Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack. Reperfusion therapy includes drugs and surgery. The drugs are thrombolytics and fibrinolytics used in a process called thrombolysis. Surgeries performed may be minimally-invasive endovascular procedures such as a percutaneous coronary intervention (PCI), which involves coronary angioplasty. The angioplasty uses the insertion of a balloon and/or stents to open up the artery. Other surgeries performed are the more invasive bypass surgeries that graft arteries around blockages.
Jonathan L. Halperin is an American cardiologist and the author of Bypass (ISBN 0-89586-509-2), among the most comprehensive works on the subject of coronary artery bypass surgery. In addition, he is the Robert and Harriet Heilbrunn Professor of Medicine at The Mount Sinai School of Medicine as well as Director of Clinical Cardiology in the Zena and Michael A. Wierner Cardiovascular Institute at The Mount Sinai Medical Center, both in New York City. Halperin was the principal cardiologist responsible for both the design and execution of the multi-center Stroke Prevention in Atrial Fibrillation (SPAF) clinical trials, funded by the National Institutes of Health, which helped develop antithrombotic strategies to prevent stroke, and he subsequently directed the SPORTIF clinical trials, which evaluated the first oral direct thrombin inhibitor for prevention of stroke in patients with atrial fibrillation.
KU Leuven is a Catholic research university in the city of Leuven, Belgium, founded in 1834 in Mechelen by the catholic bishops of Belgium "to welcome any doctrine emanating from the Holy Apostolic See and to repudiate everything that did not flow from this august source".
Hugh Christian Watkins is a British cardiologist. He is a Fellow of Merton College, Oxford, an associate editor of Circulation Research, and was Field Marshal Alexander Professor of Cardiovascular Medicine in the University of Oxford between 1996 and 2013.
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Professor Peter Sleight M.D.(Cantab.), D.M. (Oxon.) FRCP FACC was a distinguished and internationally renowned research cardiologist and an Honorary Consultant Physician at the John Radcliffe Hospital in Oxford and the Oxford University Hospitals NHS Foundation Trust. Sleight was Emeritus Field Marshal Alexander Professor of Cardiovascular Medicine at the University of Oxford and an Emeritus Fellow of Exeter College, Oxford.
Uwe Klima is UAE based professor of surgery and a faculty member at the Hannover Medical School, Germany. He also is the medical and managing director at German Heart Centre, Dubai.
John A. Ambrose is an American physician who is an expert in coronary artery disease. He is one of the pioneers in acute coronary syndromes having published over 40 articles in the cardiology literature between 1985 and 2000 on their pathogenesis. He has also published on cigarette smoking and cardiovascular disease. Working with his PhD candidate, Rajat Barua, utilizing a novel in vitro model, they described the effects of cigarette smoking on nitric oxide biosynthesis, endothelial function, and endothelial-derived fibrinolytic and antithrombotic factors. Their 2004 update on cigarette smoking and cardiovascular disease published in the Journal of the American College of Cardiology has been referenced over 2,100 times as of 2020. Ambrose is a Professor of Clinical Medicine at the University of California, San Francisco. He was also a Director of the Cardiac Catheterization Laboratory at Mount Sinai Hospital and received a National Leadership Award from the National Republican Congressional Committee.
Richard Gorlin was an American cardiologist known for his contributions to the fields of valvular heart disease, coronary artery disease and cardiac catheterization, digitalis and vasodilators in congestive heart failure, and thrombolysis in myocardial infarctions. Along with his father, developed the Gorlin formula used to calculate valve areas in aortic valve stenosis and mitral valve stenosis.
Thomas F. Lüscher is a Swiss professor of cardiology, director of research, education and development and a consultant cardiologist at the Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, and director of the Center for Molecular Cardiology at the University of Zurich.
Gemma Alexandra Figtree is an Interventional Cardiologist at Royal North Shore Hospital, Professor in Medicine at the University of Sydney, chair of the Federal Government's 10-year Mission for Cardiovascular Health, and co-leader of the Cardiovascular Theme for Sydney Health Partners.
References
- ↑ "Frans Van de Werf". orcid.org. Retrieved 22 June 2022.
- 1 2 Linde, C.; Zeymer, U.; Biondi-Zoccai, G.; Henderson, R. (January 2008). "Spotlight: Frans Van de Werf, MD, PhD". Circulation. 117 (1): f1-3. doi: 10.1161/CIRCULATIONAHA.107.188507 . ISSN 0009-7322. PMID 18172043.
- 1 2 "Profile: Frans Van de Werf, MD, PhD, FESC, FACC, FAHA". European Heart Journal. 35 (37): 2497–2503. 1 October 2014. doi: 10.1093/eurheartj/ehu289 . ISSN 0195-668X. PMID 25274321.
- ↑ "Professor Frans Van de Werf". esc365.escardio.org. Retrieved 22 June 2022.
- ↑ F1000 profile. Retrieved 30 March 2009.
- ↑ "Frans Van de Werf Fund for Clinical Cardiovascular Research". lrd.kuleuven.be. Retrieved 22 July 2022.
