Fredros Okumu | |
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Born | |
Education | BSc, MSc, PhD, MBA |
Alma mater | Moi University, Kenya University of Nairobi, Kenya London School of Hygiene & Tropical Medicine, United Kingdom |
Awards | American Society of Tropical Medicine and Hygiene Young Investigator Award (2009) |
Scientific career | |
Fields | Entomology, Parasitology, Malariology |
Institutions | Ifakara Health Institute, Tanzania |
Thesis | Combining insecticide treated bed nets and indoor residual spraying for malaria vector control in Africa |
Fredros Okumu is a Kenyan parasitologist and entomologist, who currently works as director of science at the Ifakara Health Institute (IHI) in Tanzania. His primary research interests concern the interactions between humans and mosquitoes.
Okumu began his education in his native Kenya, studying Public Health at Moi University and subsequently a masters in Applied Parasitology at the University of Nairobi. He achieved a second masters in geoscience and environmental science at Lund University, Sweden. In 2012 Okumu was awarded a PhD from the London School of Hygiene and Tropical Medicine, followed in 2019 by an MBA in International Health Management from the Swiss Tropical and Public Health Institute. [1] [2]
After leaving school Okumu entered mosquito research by working at the International Centre of Insect Physiology and Ecology. He began at the IHI during his masters research and continued through his PhD and onwards to the present day. Now he is the director of science at the institute. [1] [3] It was during his masters that Okumu developed a synthetic mosquito lure which was 3-5 times more potent than natural human odour. [4] [5] [6]
In addition to his appointment at IHI, Okumu is an associate professor at the University of the Witwatersrand, an adjunct professor at the Nelson Mandela African Institute of Science and Technology, and an Honorary Research Fellow at the University of Glasgow. [7] [8] [2] He has also been a visiting researcher at the Federal University of Minas Gerais. [1]
Okumu is an associate editor at the journal Parasites & Vectors . [9]
Okumu's research interests include the effectiveness of mosquito nets, the evolution of insecticide resistance in mosquitoes and methods of trapping and killing wild mosquitoes. [1] Okumu places a strong emphasis on the use of field studies to determine the effectiveness of mosquito-control strategies. Many devices are tested thoroughly in lab settings; however, these may not recapitulate the effects in the real world. Okumu has been involved in field studies using mosquito baits near his institute and in local villages to test their effectiveness in situ. [5] [10]
The IHI possesses the largest mosquito rearing facility in the world, known as the ‘mosquito farm’. This permits Okumu and colleagues to conduct research on mosquito population control measures on large quantities of mosquitoes. [11]
In 2010 Okumu published research of a synthetic lure which attracted mosquitoes 3-5 times more effectively than human odour control. This lure was based on components of human breath, such as carbon dioxide and ammonia. The lure was tested in local villages to establish their best effectiveness in human environments. [6] [12] Okumu was funded by Grand Challenges Canada to produce mosquito trap lures based on foot odor, since research indicates that mosquitoes are most attracted to the feet of humans. [13] [14] This produced a lot of media attention reporting the use of ‘stinky socks’ to attract and kill mosquitoes. [13] [15] [16]
Foreign Policy honoured Okumu with being a Global Thinker in 2016 for his rapid and innovative design of low-cost Aedes aegypti repellent sandals (as mosquitoes most frequently bite around the ankles) for use in Brazil to help tackle the 2015–16 Zika virus epidemic. [17] [18] [19] Okumu's research into mosquito repellants aims to develop cheap, safe and durable protection from bites using everyday objects, including footwear and even chairs. [20] [21]
Okumu studies the sexual activity of mosquitoes in order to target their mating spots. His research found that mosquitoes cluster to mate in the same locations every year, offering a promising way to identify effective settings for mosquito traps. [11] [22] [23]
Malaria is a mosquito-borne infectious disease that affects vertebrates. Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria.
N,N-Diethyl-meta-toluamide, also called diethyltoluamide or DEET, is the oldest, one of the most effective and most common active ingredient in commercial insect repellents. It is a slightly yellow oil intended to be applied to the skin or to clothing and provides protection against mosquitoes, flies, ticks, fleas, chiggers, leeches, and many other biting insects.
Aedes is a genus of mosquitoes originally found in tropical and subtropical zones, but now found on all continents except Antarctica. Some species have been spread by human activity: Aedes albopictus, a particularly invasive species, was spread to the Americas, including the United States, in the 1980s, by the used-tire trade.
Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. However, many were present in northern Europe and northern America in the 17th and 18th centuries before modern understanding of disease causation. The initial impetus for tropical medicine was to protect the health of colonial settlers, notably in India under the British Raj. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect bite, which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for most of the diseases listed here, and many do not have cures.
An insect repellent is a substance applied to the skin, clothing, or other surfaces to discourage insects from landing or climbing on that surface. Insect repellents help prevent and control the outbreak of insect-borne diseases such as malaria, Lyme disease, dengue fever, bubonic plague, river blindness, and West Nile fever. Pest animals commonly serving as vectors for disease include insects such as flea, fly, and mosquito; and ticks (arachnids).
Aedes aegypti, the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents. The mosquito can be recognized by black and white markings on its legs and a marking in the form of a lyre on the upper surface of its thorax. This mosquito originated in Africa, but is now found in tropical, subtropical and temperate regions throughout the world.
A mosquito net is a type of meshed curtain that is circumferentially draped over a bed or a sleeping area, to offer the sleeper barrier protection against bites and stings from mosquitos, flies, and other pest insects, and thus against the diseases they may carry. Examples of such preventable insect-borne diseases include malaria, dengue fever, yellow fever, zika virus, Chagas disease and various forms of encephalitis, including the West Nile virus.
Mosquito control manages the population of mosquitoes to reduce their damage to human health, economies, and enjoyment. Mosquito control is a vital public-health practice throughout the world and especially in the tropics because mosquitoes spread many diseases, such as malaria and the Zika virus.
Icaridin, also known as picaridin, is an insect repellent which can be used directly on skin or clothing. It has broad efficacy against various arthropods such as mosquitos, ticks, gnats, flies and fleas, and is almost colorless and odorless. A study performed in 2010 showed that picaridin spray and cream at the 20% concentration provided 12 hours of protection against ticks. Unlike DEET, icaridin does not dissolve plastics, synthetics or sealants, is odorless and non-greasy and presents a lower risk of toxicity when used with sunscreen, as it may reduce skin absorption of both compounds.
Electronic pest control is the name given to any of several types of electrically powered devices designed to repel or eliminate pests, usually rodents or insects. Since these devices are not regulated under the Federal Insecticide, Fungicide, and Rodenticide Act in the United States, the EPA does not require the same kind of efficacy testing that it does for chemical pesticides.
Zika fever, also known as Zika virus disease or simply Zika, is an infectious disease caused by the Zika virus. Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever. Symptoms may include fever, red eyes, joint pain, headache, and a maculopapular rash. Symptoms generally last less than seven days. It has not caused any reported deaths during the initial infection. Mother-to-child transmission during pregnancy can cause microcephaly and other brain malformations in some babies. Infections in adults have been linked to Guillain–Barré syndrome (GBS).
Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people contract mosquito-borne illnesses each year, resulting in more than a million deaths.
Zika virus is a member of the virus family Flaviviridae. It is spread by daytime-active Aedes mosquitoes, such as A. aegypti and A. albopictus. Its name comes from the Ziika Forest of Uganda, where the virus was first isolated in 1947. Zika virus shares a genus with the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Since the 1950s, it has been known to occur within a narrow equatorial belt from Africa to Asia. From 2007 to 2016, the virus spread eastward, across the Pacific Ocean to the Americas, leading to the 2015–2016 Zika virus epidemic.
Ethyl butylacetylaminopropionate is an insect repellent whose trade name is IR3535 and was developed and commercialized by Merck KGaA (Germany). It is a colorless and odorless oil with a good skin feel in final products, and it is biodegradable.
The Ifakara Health Institute (IHI) is a health research organization with offices in Ifakara, Dar es Salaam, Ikwiriri, Bagamoyo, and Mtwara, Tanzania. The institute conducts health-related research in a variety of areas, including malaria and HIV/AIDS.
The Human Development Innovation Fund is a UKAid financed 40 million British Pound challenge fund providing grants to businesses, NGOs and research institutions for scaling innovations focused on the quality, value for money, and sustainability of basic services in education, health and water, sanitation and hygiene (WASH). HDIF was launched on May 12, 2014 with the support of the Vice President of Tanzania.
Foot odor or bromodosis is a type of body odor that affects the feet of humans.
Howard Carter is a British inventor and businessman. He foundered Incognito in 2007. He is an expert in the field of insects and specifically as a mosquito bite prevention expert. After contracting two life-threatening diseases from mosquito bites, despite using a high-percentage DEET-based repellent, he was motivated to invent a totally natural, equally effective mosquito repellent, incognito anti-mosquito. This was, in part, because statistics were suggesting more mosquitoes were becoming resistant to synthetic repellents that contained controversial pesticides such as DDT and DEET.
Anopheles funestus is a species of mosquito in the Culicidae family. This species was first described in 1900 by Giles. The female is attracted to houses where it seeks out humans in order to feed on their blood, mostly during the night. This mosquito is a major vector of malaria in sub-Saharan Africa.
Heather Margaret Ferguson FRSE, Professor of Medical Entomology and Disease Ecology, at Glasgow University; a specialist in researching mosquito vectors that spread malaria, in global regions where this is endemic, aiming to manage and control a disease which the World Health Organization estimates killed over 400,000 people in 2020. Ferguson co-chairs the WHO Vector Control Advisory Group and was elected as a Fellow of the Royal Society of Edinburgh in 2021.