Fusarium graminearum genome database

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FGDB
F.graminearum.JPG
Content
Descriptiongenome resource on the plant pathogen Fusarium graminearum.
Organisms Gibberella zeae
Contact
Research center Technische Universität München
Laboratory Chair of Genome Oriented Bioinformatics, Center of Life and Food Science
Authors Ulrich Güldener
Primary citationGüldener & al. (2006) [1]
Access
Website http://mips.gsf.de/genre/proj/fusarium/.

Fusarium graminearum Genome Database (FGDB) is genomic database on Fusarium graminearum, a plant pathogen which causes the wheat headblight disease. [1]

Contents

See also

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Fusarium wilt

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<i>Fusarium</i> genus of fungi

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Common root rot is a disease of wheat caused by one or more fungi. Cochliobolus sativus, Fusarium culmorum and F. graminearum are the most common pathogens responsible for common root rot.

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<i>Gibberella zeae</i> species of fungus

Gibberella zeae, also known by the name of its anamorph Fusarium graminearum, is a plant pathogen which causes fusarium head blight, a devastating disease on wheat and barley. The pathogen is responsible for billions of dollars in economic losses worldwide each year. Infection causes shifts in the amino acid composition of wheat, resulting in shriveled kernels and contaminating the remaining grain with mycotoxins, mainly deoxynivalenol, which inhibits protein biosynthesis; and zearalenone, an estrogenic mycotoxin. These toxins cause vomiting, liver damage, and reproductive defects in livestock, and are harmful to humans through contaminated food. Despite great efforts to find resistance genes against F. graminearum, no completely resistant variety is currently available. Research on the biology of F. graminearum is directed towards gaining insight into more details about the infection process and reveal weak spots in the life cycle of this pathogen to develop fungicides that can protect wheat from scab infection.

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Vomitoxin chemical compound

Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and corn, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with Fusarium graminearum and F. culmorum, both of which are important plant pathogens which cause fusarium head blight in wheat and gibberella or fusarium ear blight in corn. A direct relationship between the incidence of fusarium head blight and contamination of wheat with deoxynivalenol has been established. The incidence of fusarium head blight is strongly associated with moisture at the time of flowering (anthesis), and the timing of rainfall, rather than the amount, is the most critical factor. However, increased amount of moisture towards harvest time has been associated with lower amount of vomitoxin in wheat grain due to leaching of toxins. Furthermore, deoxynivalenol contents are significantly affected by the susceptibility of cultivars towards Fusarium species, previous crop, tillage practices, and fungicide use. It occurs abundantly in grains in Norway due to heavy rainfall.

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References

  1. 1 2 Güldener, Ulrich; Mannhaupt Gertrud; Münsterkötter Martin; Haase Dirk; Oesterheld Matthias; Stümpflen Volker; Mewes Hans-Werner; Adam Gerhard (Jan 2006). "FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum". Nucleic Acids Res. England. 34 (Database issue): D456–8. doi:10.1093/nar/gkj026. PMC   1347389 . PMID   16381910.