Gamna–Favre bodies

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Gamna–Favre bodies are large, intracytoplasmic basophilic inclusion bodies seen in endothelial cells in patients with lymphogranuloma venereum. [1] [2]

Cytoplasm all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures

In cell biology, the cytoplasm is all of the material within a cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The main components of the cytoplasm are cytosol – a gel-like substance, the organelles – the cell's internal sub-structures, and various cytoplasmic inclusions. The cytoplasm is about 80% water and usually colorless.

Basophilic

Basophilic is a technical term used by histologists. It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with a basic dye. The most common such dye is haematoxylin.

Inclusion bodies, sometimes called elementary bodies, are nuclear or cytoplasmic aggregates of stable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. Inclusion bodies can also be hallmarks of genetic diseases, as in the case of neuronal inclusion bodies in disorders like frontotemporal dementia and Parkinson's disease.

They are named after Carlos Gamna and Maurice Favre.

Carlo Gamna (1866–1950) was an Italian physician remembered for Gandy-Gamna nodules and Gamna-Favre bodies.

Maurice Favre was a French dermatologist who gave his name to Durand-Nicolas-Favre disease, Gamna-Favre bodies and Favre–Racouchot syndrome.

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References

  1. Stedman, Thomas Lathrop (2005). Stedman's Medical Eponyms. Lippincott Williams & Wilkins. p. 260. ISBN   9780781754439 . Retrieved 13 November 2017.
  2. Hoang, Mai P.; Selim, Maria Angelica (2014). Vulvar Pathology. Springer. p. 167. ISBN   9781493918072 . Retrieved 13 November 2017.