The Global Leaders Group on Antimicrobial Resistance consists of world leaders and experts from across sectors working together to accelerate political action on antimicrobial resistance (AMR). [1] [2] [3]
The Group performs an independent global advisory and advocacy role and works to maintain urgency, public support, political momentum and visibility of the AMR challenge on the global health and development agenda.
"The Global Leaders Group on Antimicrobial Resistance collaborates globally with governments, agencies, civil society and the private sector through a One Health approach to advise on and advocate for prioritized political actions for the mitigation of drug resistant infections through responsible and sustainable access to and use of antimicrobials." [4]
The Global Leaders Group on Antimicrobial Resistance was established in November 2020 [5] [6] [7] following the recommendation of the Interagency Coordination Group on Antimicrobial Resistance to strengthen global political momentum and leadership on AMR. The inaugural meeting of the Group took place in January 2021. [8]
The Quadripartite Joint Secretariat (QJS) on Antimicrobial Resistance, [9] a joint effort by the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP),the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH) provide secretariat support for the Group.
The Global Leaders Group on Antimicrobial Resistance is chaired by Her Excellency Mia Amor Mottley, Prime Minister of Barbados. [10]
The Group includes members from across different sectors and countries [11] including heads of state, serving or former ministers and/or senior government officials (acting in their individual capacities), senior representatives of foundations and civil society organizations and leaders from the private sector.
Current Group members: [12]
Antimicrobial resistance (AMR) occurs when microbes evolve mechanisms that protect them from the effects of antimicrobials. All classes of microbes can evolve resistance where the drugs are no longer effective. Fungi evolve antifungal resistance, viruses evolve antiviral resistance, protozoa evolve antiprotozoal resistance, and bacteria evolve antibiotic resistance. Together all of these come under the umbrella of antimicrobial resistance. Microbes resistant to multiple antimicrobials are called multidrug resistant (MDR) and are sometimes referred to as superbugs. Although antimicrobial resistance is a naturally occurring process, it is often the result of improper usage of the drugs and management of the infections.
The Food and Agriculture Organization of the United Nations (FAO) is a specialized agency of the United Nations that leads international efforts to defeat hunger and improve nutrition and food security. Its Latin motto, fiat panis, translates to "let there be bread". It was founded on 16 October 1945.
The Colombo Plan is a regional intergovernmental organization that began operations on 1 July 1951. The organization was conceived at an international conference, The Commonwealth Conference on Foreign Affairs held in Colombo, Ceylon in January 1950, and was attended by the finance ministers of Australia, the United Kingdom, Canada, Ceylon, Pakistan and New Zealand, and the prime ministers of Ceylon and India. Membership has expanded significantly over the years to the current 28 governments.
Julie Louise Gerberding is an American infectious disease expert who was the first woman to serve as the director of the U.S. Centers for Disease Control and Prevention (CDC). As of May 2022, she is the CEO of the Foundation for the National Institutes of Health (FNIH). Gerberding grew up in Estelline, South Dakota, attended Brookings High School, and earned undergraduate and graduate degrees from Case Western Reserve University. She was the chief medical resident at the University of California, San Francisco where she treated hospitalized AIDS patients in the first years of the epidemic. Gerberding became a nationally-recognized figure during the 2001 anthrax attacks in the United States during her tenure as the acting deputy director of the National Center for Infectious Diseases, where she was a prominent spokeswoman for the CDC during daily briefings regarding the attacks and aftermath. Gerberding then served as CDC director from 2002-2009, and was then hired as an administrator at Merck.
Global health is the health of the populations in the worldwide context; it has been defined as "the area of study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide". Problems that transcend national borders or have a global political and economic impact are often emphasized. Thus, global health is about worldwide health improvement, reduction of disparities, and protection against global threats that disregard national borders, including the most common causes of human death and years of life lost from a global perspective.
The Union for International Cancer Control or UICC is a non-governmental organisation with some 1,180 member organisations in more than 170 countries.
The Society for International Development (SID) was founded in Washington, D.C., United States, in 1957.
Lena Ingeborg Hallengren is a Swedish politician of the Social Democratic Party who has been served as Minister for Health and Social Affairs in the cabinet of Prime Minister Stefan Löfven from 21 January 2019 until he left office in November 2021. Hallengren then continued in the same role in the Andersson Cabinet.
One Health Trust, formerly the Center for Disease Dynamics, Economics & Policy, is a public health research organization with offices in Washington, D.C., New Delhi, and Bangalore, India.
One Health is an approach calling for "the collaborative efforts of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals and our environment", as defined by the One Health Initiative Task Force (OHITF). It developed in response to evidence of the spreading of zoonotic diseases between species and increasing awareness of "the interdependence of human and animal health and ecological change". In this viewpoint, public health is no longer seen in purely human terms. Due to a shared environment and highly conserved physiology, animals and humans not only suffer from the same zoonotic diseases, but can also be treated by either structurally related or identical drugs. For this reason, special care must be taken to avoid unnecessary or over-treatment of zoonotic diseases, particularly in the context of drug resistance in infectious microbes.
Amina Jane Mohammed is a British Nigerian diplomat and politician who is serving as the fifth Deputy Secretary-General of the United Nations. Previously, she was Nigerian Minister of Environment from 2015 to 2016 and was a player in the Post-2015 Development Agenda process. She is also Chair of United Nations Sustainable Development Group.
Onyebuchi Chukwu is a Nigerian politician who served as Minister of Health from 2010 until 2014.
Antibiotic use in livestock is the use of antibiotics for any purpose in the husbandry of livestock, which includes treatment when ill (therapeutic), treatment of a group of animals when at least one is diagnosed with clinical infection (metaphylaxis), and preventative treatment (prophylaxis). Antibiotics are an important tool to treat animal as well as human disease, safeguard animal health and welfare, and support food safety. However, used irresponsibly, this may lead to antibiotic resistance which may impact human, animal and environmental health.
The Arab Forum for Environment and Development (AFED) is a not-for-profit regional non-governmental organization, membership-based organization headquartered in Beirut, Lebanon, with the status of international organization; grouping experts together with the civil society, business community and media, to promote prudent environmental policies and programmes across the Arab region.
Dasho Dechen Wangmo is a Bhutanese politician who has been Minister for Health since November 2018. She has been a member of the National Assembly of Bhutan, since October 2018.
Antimicrobial resistance (AMR) directly kills about 1,600 people each year in Australia. This is a currently serious threat to both humans and animals in the country. Antimicrobial resistance occurs when a microorganism evolves and gains the ability to become more resistant or completely resistant to the medicine that was previously used to treat it. Drug-resistant bacteria are increasingly difficult to treat, requiring replacement or higher-dose drugs that may be more expensive or more toxic. Resistance can develop through one of the three mechanisms: natural resistant ability in some types of microorganisms, a mutation in genes or receiving the resistance from another species. Antibodies appear naturally due to random mutations, or more often after gradual accumulation over time, and because of abuse of antibiotics. Multidrug-resistance, or MDR, are the microorganisms that are resistant to many types of antimicrobials. "Superbugs" is the term also used for multidrug-resistant microbes, or totally drug-resistant (TDR).
The Society of Infectious Diseases Pharmacists (SIDP) is a non-profit association of pharmacists and other allied health professionals who specialize in infectious diseases and antimicrobial stewardship. According to the Board of Pharmaceutical Specialties, clinical pharmacists specializing in infectious diseases are trained in the use of microbiology and pharmacology to develop, implement, and monitor drug regimens that incorporate the pharmacodynamics and pharmacokinetics of antimicrobials for patients.
Nicolae Ștefănuță is a Romanian politician who has been serving as a Member of the European Parliament since 2019.
Alison Helen Holmes is a British infectious diseases specialist, who is a professor at Imperial College London and the University of Liverpool. Holmes serves as Director of the National Institute for Health Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance and Consultant at Hammersmith Hospital. Holmes is on the Executive Committee of the International Society of Infectious Diseases, and she serves on a variety of World Health Organization (WHO) expert groups related to antimicrobial use, Antimicrobial Resistance (AMR), infection prevention and sepsis. Her research considers how to mitigate antimicrobial resistance.
Lothar Heinz Wieler is a German veterinarian and microbiologist who served as president of the Robert Koch Institute (RKI) from 2015 to 2023. In this capacity, he advised the German Federal and State Governments on topics of public health, especially infection hazards, and on the containment of the COVID-19 pandemic.