Grey's Anatomy season 22

Last updated

Contents

Grey's Anatomy
Season 22
Greys Anatomy season 22 promotional poster.jpg
Promotional poster
ShowrunnerMeg Marinis
Starring
Release
Original network ABC
Original releaseOctober 9, 2025 (2025-10-09)
Season chronology
← Previous
Season 21
List of episodes

The twenty-second season of the American medical drama television series Grey's Anatomy was announced on April 3, 2025, and premieres in the United States on the American Broadcasting Company (ABC) on October 9, 2025. [1] [2]

This is the first season not to feature Jake Borelli and Midori Francis as series regulars since the sixteenth and nineteenth seasons, respectively. [3]

Cast and characters

Main

Recurring

Guest

Episodes

No.
overall		No. in
season		Title  [8] Directed byWritten by  [9] Original release date  [8] U.S. viewers
(millions)
4491"Only the Strong Survive" Debbie Allen Meg MarinisOctober 9, 2025 (2025-10-09)TBD
After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.
4502"We Built This City" Kevin McKidd Zoanne Clack October 16, 2025 (2025-10-16)TBD
The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.
4513"Between Two Lungs"Debbie AllenSandra HamadaOctober 23, 2025 (2025-10-23)TBD
4524"Goodbye Horses" Sammi Cannold Jase Miles-PerezOctober 30, 2025 (2025-10-30)TBD
4535"Sometimes I Feel Like a Motherless Child" Bille Woodruff TBANovember 6, 2025 (2025-11-06)TBD
4546TBA Phylicia Rashad TBANovember 13, 2025 (2025-11-13)TBD
4557TBAKevin McKiddTBANovember 20, 2025 (2025-11-20)TBD

Production

Development

On April 3, 2025, ABC renewed the series for a twenty-second season with Meg Marinis third year as showrunner. [1] The season consists of 18 episodes, consistent with the episode order of Season 21. [10] It will also surpass the 450 episode mark during episode 2, extending its record as the longest-running American primetime medical drama. [11] Filming began on August 1. [12] Season 22 premieres in the United States on October 9, 2025. [13]

Casting

Ellen Pompeo will continue to narrate the series and receive star billing, appearing in seven episodes, as she did in Season 21. [14] Chandra Wilson and James Pickens Jr. remain the only original cast members confirmed to appear in all 18 episodes. [15]

Reception

Ratings

Viewership and ratings per episode of Grey's Anatomy season 22
No.TitleAir dateTimeslot (ET) Rating/share
(18–49)		Viewers
(millions)		DVR
(18–49)		DVR viewers
(millions)		Total
(18–49)		Total viewers
(millions)
1"Only the Strong Survive"October 9, 2025Thursday
10:00 p.m.		——————
2"We Built This City"October 16, 2025——————
3"Between Two Lungs"October 23, 2025——————
4"Goodbye Horses"October 30, 2025——————
5"Sometimes I Feel Like a Motherless Child"November 6, 2025——————

References

  1. 1 2 Otterson, Joe (April 3, 2025). "'9-1-1,' 'Grey's Anatomy,' 'The Rookie,' 'Shifting Gears,' 'Will Trent' Renewed at ABC". Variety . Retrieved July 15, 2025.
  2. ↑ White, Peter (July 29, 2025). "ABC Moves Up 'Grey's Anatomy', '9-1-1' & '9-1-1: Nashville' Premiere Dates". Deadline Hollywood . Retrieved July 29, 2025.
  3. ↑ Venable, Malcom (December 4, 2024). "'Grey's Anatomy' Showrunner Meg Marinis on That Shocking Mid-Season Finale, Two Big Departures, and What's Coming Next". Shondaland . Retrieved July 22, 2025.
  4. ↑ Roots, Kimberly; Swift, Andy; Matt, Mitovich; Nemetz, Dave; Franken, Claire; Schwartz, Ryan; Caruso, Nick; Mason, Charlie (September 10, 2025). "Fall TV Preview 2025: Exclusive Scoop and Photos on 30+ Returning Favorites!". TVLine . Retrieved September 11, 2025.
  5. ↑ Andreeva, Nellie (April 1, 2025). "'Grey's Anatomy': Trevor Jackson Joins Cast Of ABC Medical Drama". Deadline Hollywood . Retrieved July 21, 2025.
  6. ↑ Gomez, Patrick (August 29, 2025). "Who survived the Grey's Anatomy explosion? An exclusive look at the season 22 premiere reveals clues". Entertainment Weekly . Retrieved August 29, 2025.
  7. ↑ "CURTIS EDWARD JACKSON - SAG-AFTRA". Breakdown Express. Retrieved August 25, 2025.
  8. 1 2 "Shows A-Z – Grey's Anatomy on ABC". The Futon Critic . Retrieved October 2, 2025.
  9. ↑ "Grey's Anatomy". Writers Guild of America West . Retrieved October 6, 2025.
  10. ↑ Andreeva, Nellie (April 3, 2025). "'Grey's Anatomy' Renewed For Season 22 By ABC With Veteran Cast Poised To Return". Deadline Hollywood . Retrieved July 21, 2025.
  11. ↑ Levine, Daniel; Hyman, Lizzie (May 14, 2025). "Chandra Wilson Says After 20 Years, 'It Is Time' to Watch Grey's Anatomy for Herself: 'Got as Far as Season 3' (Exclusive)". People Magazine . Retrieved July 21, 2025.
  12. ↑ Camilla Luddington [@camillaluddington]; (July 31, 2025). "Backstory… Tonight I'm re-watching the season finale again to prepare for filming tmw. And suddenly.. Matt decides he needs to blend a smoothie. At 8pm.. during this scene.. I had to start recording 😂" . Retrieved August 10, 2025– via Instagram.
  13. ↑ Shanfeld, Ethan (July 29, 2025). "'Grey's Anatomy,' '9-1-1' and '9-1-1: Nashville' Move Up Premiere Dates on ABC". Variety . Retrieved July 29, 2025.
  14. ↑ Gao, Max (April 29, 2025). "Ellen Pompeo on Her Lasting Legacy, the 'Really S—ty' Streaming Residual Model and Meredith's Choice This Season She Was 'Deeply Against'". Variety. Retrieved July 21, 2025.
  15. ↑ Bell, Amanda (July 17, 2025). "'Grey's Anatomy' Season 22 Premiere Date Revealed". TV Insider. Retrieved July 21, 2025.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.