Hedgehog (disambiguation)

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A hedgehog is a small, spiny mammal.

Hedgehog may also refer to:

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Sonic the Hedgehog (character) Video game character

Sonic the Hedgehog is a fictional character and the protagonist of the Sonic the Hedgehog video game series published by Sega, as well as numerous spin-off comics, animations, and other media. Sonic is a blue anthropomorphic hedgehog who can run at supersonic speeds and curl into a ball, primarily to attack enemies. In most games, Sonic must race through levels, collecting power-up rings and avoiding obstacles and enemies.

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Sonic hedgehog Protein-coding gene in the species Homo sapiens

Sonic hedgehog is a protein that in humans is encoded by the SHH gene. It is the best-studied ligand of the hedgehog signaling pathway others being desert hedgehog (DHH) and Indian hedgehog (IHH). It plays a key role in the development of animals from insects to mammals. In vertebrates it is involved in organogenesis including the growth of digits on limbs and the organization of the brain. Sonic hedgehog is an archetypal example of a morphogen as defined by Lewis Wolpert's French flag model—a molecule that diffuses to form a concentration gradient and has different effects on the cells of the developing embryo depending on its concentration. Sonic hedgehog is also active in adults; for example it controls the proliferation of adult stem cells and has been implicated in the development of some cancers.

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<i>Shadow the Hedgehog</i> (video game) 2005 video game

Shadow the Hedgehog is a 2005 platform game developed by Sega Studios USA, the former United States division of Sonic Team, and published by Sega. It is a spin-off from the Sonic the Hedgehog series and follows Shadow the Hedgehog, a creation of Doctor Eggman's grandfather, Prof. Gerald Robotnik, as he attempts to learn about his past while suffering from amnesia. Shadow the Hedgehog introduces third-person shooter elements and nonlinear gameplay to the Sonic franchise. To defeat enemies, Shadow can use various weapons and special attacks, and most levels have three possible missions that the player may choose to complete. The missions completed determine the game's plot and subsequently playable levels.

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Sonic the Hedgehog is a media franchise created by Sega.

The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.

Smoothened

Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a Class Frizzled G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the natural teratogen cyclopamine. It also is the target of Vismodegib, the first hedgehog pathway inhibitor to be approved by the U.S. Food and Drug Administration (FDA).

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Doctor Eggman Fictional character from Sonic franchise

Doctor Ivo "Eggman" Robotnik is a fictional character and the main antagonist of Sega's Sonic the Hedgehog series. Eggman was created and designed by Naoto Ohshima as part of many design choices for Sega's new mascot. After the creation of Sonic the Hedgehog, Ohshima chose to use his previous egg-shaped character to create the antagonist of the 1991 video game Sonic the Hedgehog, making him the archenemy of the series' eponymous main character.

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