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| Discipline | Chemistry |
|---|---|
| Language | English |
| Edited by | Eva Hevia, Jérôme Waser |
| Publication details | |
| History | 1918–present |
| Publisher | John Wiley & Sons (Switzerland) |
| Frequency | Monthly |
| 1.5 (2023) | |
| Standard abbreviations | |
| ISO 4 | Helv. Chim. Acta |
| Indexing | |
| ISSN | 0018-019X |
| Links | |
Helvetica Chimica Acta is a peer-reviewed scientific journal of chemistry established by the Swiss Chemical Society. It is published online by John Wiley & Sons. The journal has a 2023 impact factor of 1.5. [1]
Leopold Ružička was a Croatian-Swiss scientist and joint winner of the 1939 Nobel Prize in Chemistry "for his work on polymethylenes and higher terpenes" "including the first chemical synthesis of male sex hormones." He worked most of his life in Switzerland, and received eight doctorates honoris causa in science, medicine, and law; seven prizes and medals; and twenty-four honorary memberships in chemical, biochemical, and other scientific societies.
Jack David Dunitz FRS was a British chemist and widely known chemical crystallographer. He was Professor of Chemical Crystallography at the ETH Zurich from 1957 until his official retirement in 1990. He held Visiting Professorships in the United States, Israel, Japan, Canada, Spain and the United Kingdom.
Etonitazene, also known as EA-4941 or CS-4640, is a benzimidazole opioid, first reported in 1957, that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals.
Mesoridazine(Serentil) is a phenothiazine class drug that is used in the treatment of schizophrenia. It is one of the active metabolites of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure.
[n]Radialenes are alicyclic organic compounds containing n cross-conjugated exocyclic double bonds. The double bonds are commonly alkene groups but those with a carbonyl (C=O) group are also called radialenes. For some members the unsubstituted parent radialenes are elusive but many substituted derivatives are known.
Rolf Huisgen was a German chemist. His importance in synthetic organic chemistry extends to the enormous influence he had in post-war chemistry departments in Germany and Austria, due to a large number of his habilitants becoming professors. His major achievement was the development of the 1,3-dipolar cycloaddition reaction, also called the Huisgen cycloaddition.
Albert Jakob Eschenmoser (5 August 1925 – 14 July 2023) was a Swiss organic chemist, best known for his work on the synthesis of complex heterocyclic natural compounds, most notably vitamin B12. In addition to his significant contributions to the field of organic synthesis, Eschenmoser pioneered work in the Origins of Life (OoL) field with work on the synthetic pathways of artificial nucleic acids. Before retiring in 2009, Eschenmoser held tenured teaching positions at the ETH Zurich and The Skaggs Institute for Chemical Biology at The Scripps Research Institute in La Jolla, California as well as visiting professorships at the University of Chicago, Cambridge University, and Harvard.
Mepindolol (Betagon) is a non-selective beta blocker. It is used to treat glaucoma.
Clotiapine (Entumine) is an atypical antipsychotic of the dibenzothiazepine chemical class. It was first introduced in a few European countries, Argentina, Taiwan and Israel in 1970.
Roman Kaiser is a Swiss fragrance chemist. Since 1968 he has been working at Givaudan, the world's largest company in the flavour and fragrance industry, where he analyzes and reconstitutes natural scents for use in perfumery using the headspace technology which he pioneered and which as a new concept made significant impact on the analysis of natural products.
The total synthesis of the complex biomolecule vitamin B12 was accomplished in two different approaches by the collaborating research groups of Robert Burns Woodward at Harvard and Albert Eschenmoser at ETH in 1972. The accomplishment required the effort of no less than 91 postdoctoral researchers (Harvard: 77, ETH: 14), and 12 Ph.D. students (at ETH) from 19 different nations over a period of almost 12 years. The synthesis project induced and involved a major change of paradigm in the field of natural product synthesis.
Helmut Schwarz is a German organic chemist. He has been a professor of chemistry at the Technische Universität Berlin since 1978. In 2018, he was elected a foreign associate of the U.S. National Academy of Sciences.
Alfred Berthoud (1874–1939) was a Swiss chemist, professor of chemistry at the University of Neuchâtel.
Günther Ohloff was a prominent German fragrance chemist.
Friedrich Fichter was a professor of inorganic chemistry at the University of Basel. His main field of interest was electrochemistry. He initiated the founding of the scientific journal Helvetica Chimica Acta.
The Italian Chemical Society is the national association in Italy representing the chemical sciences. Its main aim is to promote and support the development of chemistry and scientific research, spreading the knowledge of chemistry and its applications in order to improve the welfare of the country, establishing and maintaining relations with organizations from other countries with similar purposes and promoting the study of this subject at school and university.
Lotte Luise Friederike Loewe was a German chemist known for her published research in organic chemistry.
Isotonitazene is a benzimidazole-derived opioid analgesic drug related to etonitazene, which has been sold as a designer drug. It has only around half the potency of etonitazene in animal studies, but it is likely even less potent in humans as was seen with etonitazene. Isotonitazene was fully characterized in November 2019 in a paper where the authors performed a full analytical structure elucidation in addition to determination of the potency at the μ-opioid receptor using a biological functional assay in vitro. While isotonitazene was not compared directly to morphine in this assay, it was found to be around 2.5 times more potent than hydromorphone and slightly more potent than fentanyl.
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