The hotcross bun sign is a radiologic sign observed on transverse T2-weighted magnetic resonance (MR) images of the brain, describing a cross-shaped (or cruciform) hyperintensity within the pons. This sign is most commonly associated with the cerebellar subtype of multiple system atrophy (MSA-c). [1] It is also associated with spinocerebellar ataxia, progressive multifocal leukoencephalopathy, paraneoplastic cerebellar degeneration, and Creutzfeldt-Jakob disease. [2]
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum.
A computed tomography scan, formerly called computed axial tomography scan, is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or radiology technologists.
Radiology is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography, but today it includes all imaging modalities. This includes technologies that use no ionizing electromagnetic radiation, such as ultrasonography and magnetic resonance imaging), as well as others that do use radiation, such as computed tomography (CT), fluoroscopy, and nuclear medicine including positron emission tomography (PET). Interventional radiology is the performance of usually minimally invasive medical procedures with the guidance of imaging technologies such as those mentioned above.
In neurology, the Chiari malformation is a structural defect in the cerebellum, characterized by a downward displacement of one or both cerebellar tonsils through the foramen magnum.
A hot cross bun is a spiced bun, usually containing small pieces of raisins and marked with a cross on the top, which has been traditionally eaten on Good Friday in the United Kingdom, Ireland, Australia, New Zealand, South Africa, Canada, India, Pakistan, Malta, United States and the Commonwealth Caribbean. They are available all year round in some countries, including the UK.
The Anglo-Arabian, also known as the Anglo-Arab, is a horse breed that originated in France by cross-breeding a Thoroughbred with an Arabian. The Anglo-Arabian has origins tracing back to the Limousin Horse. It was officially recognized by Emperor Louis Philippe I and produced by the Haras National du Pin. The Anglo-Arabian has long legs, a refined head, larger hindquarters, and are most commonly seen in gray, bay, or chestnut. To be recognized as an Anglo-Arabian with the Arabian Horse Association, the horse must have at least 25% Arabian blood. There are no color or height restrictions to be registered. Due to its lineage and physique, the Anglo-Arabian is utilized for sports-related activities such as dressage, show jumping, endurance, and cross-country.
The inferior olivary nucleus (ION) is a structure found in the medulla oblongata underneath the superior olivary nucleus. In vertebrates, the ION is known to coordinate signals from the spinal cord to the cerebellum to regulate motor coordination and learning. These connections have been shown to be tightly associated, as degeneration of either the cerebellum or the ION results in degeneration of the other.
The cerebellar vermis is located in the medial, cortico-nuclear zone of the cerebellum, which is in the posterior fossa of the cranium. The primary fissure in the vermis curves ventrolaterally to the superior surface of the cerebellum, dividing it into anterior and posterior lobes. Functionally, the vermis is associated with bodily posture and locomotion. The vermis is included within the spinocerebellum and receives somatic sensory input from the head and proximal body parts via ascending spinal pathways.
Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central nervous system and meninges. The term congophilic is sometimes used because the presence of the abnormal aggregations of amyloid can be demonstrated by microscopic examination of brain tissue after staining with Congo red. The amyloid material is only found in the brain and as such the disease is not related to other forms of amyloidosis.
Hot Cross Buns was an English street cry, later perpetuated as a nursery rhyme and an aid in musical education. It refers to the spiced English confection known as a hot cross bun, which is associated with the end of Lent and is eaten on Good Friday in various countries. The song has the Roud Folk Song Index number of 13029.
Dandy–Walker malformation (DWM), also known as Dandy–Walker syndrome (DWS), is a rare congenital brain malformation in which the part joining the two hemispheres of the cerebellum does not fully form, and the fourth ventricle and space behind the cerebellum are enlarged with cerebrospinal fluid. Most of those affected develop hydrocephalus within the first year of life, which can present as increasing head size, vomiting, excessive sleepiness, irritability, downward deviation of the eyes and seizures. Other, less common symptoms are generally associated with comorbid genetic conditions and can include congenital heart defects, eye abnormalities, intellectual disability, congenital tumours, other brain defects such as agenesis of the corpus callosum, skeletal abnormalities, an occipital encephalocele or underdeveloped genitalia or kidneys. It is sometimes discovered in adolescents or adults due to mental health problems.
The meningeal branches of vertebral artery springs from the vertebral opposite the foramen magnum, ramifies between the bone and dura mater in the cerebellar fossa, and supplies the falx cerebelli.
A radiologic sign is an objective indication of some medical fact that is detected by a physician during radiologic examination with medical imaging.
Lateral pontine syndrome, also known as Marie-Foix syndrome or Marie-Foix-Alajouanine syndrome is one of the brainstem stroke syndromes of the lateral aspect of the pons. A lateral pontine syndrome is a lesion which is similar to the lateral medullary syndrome, but because it occurs in the pons, it also involves the cranial nerve nuclei of the pons.
Lhermitte–Duclos disease (LDD), also called dysplastic gangliocytoma of the cerebellum (DGC), is a rare, slowly growing tumor of the cerebellum, a gangliocytoma sometimes considered to be a hamartoma, characterized by diffuse hypertrophy of the granular layer of the cerebellum. It is often associated with Cowden syndrome. It was described by Jacques Jean Lhermitte and P. Duclos in 1920.
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder most frequently seen in male premutation carriers of Fragile X syndrome (FXS) over the age of 50. The main clinical features of FXTAS include problems of movement with cerebellar gait ataxia and action tremor. Associated features include parkinsonism, cognitive decline, and dysfunction of the autonomic nervous system. FXTAS is found in Fragile X "premutation" carriers, which is defined as a trinucleotide repeat expansion of 55-200 CGG repeats in the Fragile X mental retardation-1 (FMR1) gene. 4-40 CGG repeats in this gene is considered normal, while individual with >200 repeats have full Fragile X Syndrome.
Radiopaedia is a wiki-based international collaborative educational web resource containing a radiology encyclopedia and imaging case repository. It is currently the largest freely available radiology related resource in the world with more than 50,000 patient cases and over 16,000 reference articles on radiology-related topics. The open edit nature of articles allows radiologists, radiology trainees, radiographers, sonographers, and other healthcare professionals interested in medical imaging to refine most content through time. An editorial board peer reviews all contributions.
Raymond–Céstan syndrome is caused by blockage of the long circumferential branches of the basilar artery. It was described by Fulgence Raymond and Étienne Jacques Marie Raymond Céstan. Along with other related syndromes such as Millard–Gubler syndrome, Foville's syndrome, and Weber's syndrome, the description was instrumental in establishing important principles in brain-stem localization.
Medical imaging in pregnancy may be indicated because of pregnancy complications, intercurrent diseases or routine prenatal care.