Pons

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Pons
Brain bulbar region.svg
Pons in the brainstem
Gray679.png
Details
Part of Brain stem
Artery pontine arteries
Vein transverse and lateral pontine veins
Identifiers
MeSH D011149
NeuroNames 547
NeuroLex ID birnlex_733
TA98 A14.1.03.010
TA2 5921
FMA 67943
Anatomical terms of neuroanatomy

The pons (pl.: pontes; from Latin pons, "bridge") is part of the brainstem that in humans and other mammals, lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum.

Contents

The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75). [1] This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus. [2]

Structure

The pons in humans measures about 2.5 centimetres (0.98 in) in length. [2] It is the part of the brainstem situated between the midbrain and the medulla oblongata, [3] and in front of the cerebellum.[ citation needed ] The horizontal medullopontine sulcus demarcates the boundary between the pons and medulla oblongata on the ventral aspect of the brainstem, and the roots of cranial nerves VI/VII/VIII emerge from the brainstem along this groove. [4] The junction of pons, medulla oblongata, and cerebellum forms an angle - the cerebellopontine angle. [5] The superior pontine sulcus separates the pons from the midbrain. [6] Posteriorly, the pons curves on either side into a middle cerebellar peduncle. [3]

The pons can be broadly divided into two parts: the basilar part of the pons (ventral pons), [7] and the pontine tegmentum (dorsal pons). [8]

The ventral aspect of the pons faces the clivus, with the pontine cistern intervening between the two structures. The ventral surface of the pons features a midline basilar sulcus along which the basilar artery may or may not course. There is a bulge to either side of the basilar sulcus, created by the pontine nuclei that are interweaved amid the descending fibres within the substance of the pons. The superior cerebellar artery winds around the upper margin of the pons. [3]

Vasculature

Most of the pons is supplied by the pontine arteries, which arise from the basilar artery. A smaller portion of the pons is supplied by the anterior and posterior inferior cerebellar arteries.

Development

During embryonic development, the metencephalon develops from the rhombencephalon and gives rise to two structures: the pons and the cerebellum. [2] The alar plate produces sensory neuroblasts, which will give rise to the solitary nucleus and its special visceral afferent (SVA) column; the cochlear and vestibular nuclei, which form the special somatic afferent (SSA) fibers of the vestibulocochlear nerve, the spinal and principal trigeminal nerve nuclei, which form the general somatic afferent column (GSA) of the trigeminal nerve, and the pontine nuclei which relays to the cerebellum.

Basal plate neuroblasts give rise to the abducens nucleus, which forms the general somatic efferent fibers (GSE); the facial and motor trigeminal nuclei, which form the special visceral efferent (SVE) column, and the superior salivatory nucleus, which forms the general visceral efferent fibers (GVE) of the facial nerve.

Nuclei

Cross-section of lower pons, axons shown in blue, grey matter in light grey. Anterior is down and posterior is up Lower pons horizontal KB.svg
Cross-section of lower pons, axons shown in blue, grey matter in light grey. Anterior is down and posterior is up

A number of cranial nerve nuclei are present in the pons:

Function

Functions of these four cranial nerves (V-VIII) include regulation of respiration, control of involuntary actions, sensory roles in hearing, equilibrium, and taste, and in facial sensations such as touch and pain, as well as motor roles in eye movement, facial expressions, chewing, swallowing, and the secretion of saliva and tears. [2]

The pons contains nuclei that relay signals from the forebrain to the cerebellum, along with nuclei that deal primarily with sleep, respiration, swallowing, bladder control, hearing, equilibrium, taste, eye movement, facial expressions, facial sensation, and posture. [2]

Within the pons is the pneumotaxic center consisting of the subparabrachial and the medial parabrachial nuclei. This center regulates the change from inhalation to exhalation. [2]

The pons is implicated in sleep paralysis, and may also play a role in generating dreams. [9]

Clinical significance

Other animals

Evolution

The pons first evolved as an offshoot of the medullary reticular formation. [10] Since lampreys possess a pons, it has been argued that it must have evolved as a region distinct from the medulla by the time the first agnathans appeared, 525 million years ago. [11]

Additional images

Related Research Articles

<span class="mw-page-title-main">Medulla oblongata</span> Structure of the brain stem

The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing. The medulla contains the cardiac, respiratory, vomiting and vasomotor centers, and therefore deals with the autonomic functions of breathing, heart rate and blood pressure as well as the sleep–wake cycle.

<span class="mw-page-title-main">Facial nerve</span> Cranial nerve VII, for the face and tasting

The facial nerve, also known as the seventh cranial nerve, cranial nerve VII, or simply CN VII, is a cranial nerve that emerges from the pons of the brainstem, controls the muscles of facial expression, and functions in the conveyance of taste sensations from the anterior two-thirds of the tongue. The nerve typically travels from the pons through the facial canal in the temporal bone and exits the skull at the stylomastoid foramen. It arises from the brainstem from an area posterior to the cranial nerve VI and anterior to cranial nerve VIII.

Articles related to anatomy include:

<span class="mw-page-title-main">Brainstem</span> Posterior part of the brain, adjoining and structurally continuous

The brainstem is the stalk-like part of the brain that interconnects the cerebrum and diencephalon with the spinal cord. In the human brain, the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch.

<span class="mw-page-title-main">Trigeminal nerve</span> Cranial nerve responsible for the faces senses and motor functions

In neuroanatomy, the trigeminal nerve (lit. triplet nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewing; it is the most complex of the cranial nerves. Its name (trigeminal, from Latin tri- 'three', and -geminus 'twin') derives from each of the two nerves (one on each side of the pons) having three major branches: the ophthalmic nerve (V1), the maxillary nerve (V2), and the mandibular nerve (V3). The ophthalmic and maxillary nerves are purely sensory, whereas the mandibular nerve supplies motor as well as sensory (or "cutaneous") functions. Adding to the complexity of this nerve is that autonomic nerve fibers as well as special sensory fibers (taste) are contained within it.

<span class="mw-page-title-main">Vestibulocochlear nerve</span> Cranial nerve VIII, for hearing and balance

The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. Through olivocochlear fibers, it also transmits motor and modulatory information from the superior olivary complex in the brainstem to the cochlea.

<span class="mw-page-title-main">Glossopharyngeal nerve</span> Cranial nerve IX, for the tongue and pharynx

The glossopharyngeal nerve, also known as the ninth cranial nerve, cranial nerve IX, or simply CN IX, is a cranial nerve that exits the brainstem from the sides of the upper medulla, just anterior to the vagus nerve. Being a mixed nerve (sensorimotor), it carries afferent sensory and efferent motor information. The motor division of the glossopharyngeal nerve is derived from the basal plate of the embryonic medulla oblongata, whereas the sensory division originates from the cranial neural crest.

<span class="mw-page-title-main">Cerebral peduncle</span> Stalks that attach the cerebrum to the brainstem

The cerebral peduncles are the two stalks that attach the cerebrum to the brainstem. They are structures at the front of the midbrain which arise from the ventral pons and contain the large ascending (sensory) and descending (motor) nerve tracts that run to and from the cerebrum from the pons. Mainly, the three common areas that give rise to the cerebral peduncles are the cerebral cortex, the spinal cord and the cerebellum. The region includes the tegmentum, crus cerebri and pretectum. By this definition, the cerebral peduncles are also known as the basis pedunculi, while the large ventral bundle of efferent fibers is referred to as the cerebral crus or the pes pedunculi.

<span class="mw-page-title-main">Solitary nucleus</span> Sensory nuclei in medulla oblongata

The solitary nucleus is a series of sensory nuclei forming a vertical column of grey matter in the medulla oblongata of the brainstem. It receives general visceral and/or special visceral inputs from the facial nerve, glossopharyngeal nerve and vagus nerve ; it receives and relays stimuli related to taste and visceral sensation. It sends outputs to various parts of the brain, such as the hypothalamus, thalamus, and reticular formation. Neuron cell bodies of the SN are roughly somatotopically arranged along its length according to function.

<span class="mw-page-title-main">Corticobulbar tract</span> Motor pathway in the brain connecting the motor cortex to the medullary pyramids

In neuroanatomy, the corticobulbartract is a two-neuron white matter motor pathway connecting the motor cortex in the cerebral cortex to the medullary pyramids, which are part of the brainstem's medulla oblongata region, and are primarily involved in carrying the motor function of the non-oculomotor cranial nerves. The corticobulbar tract is one of the pyramidal tracts, the other being the corticospinal tract.

<span class="mw-page-title-main">Reticular formation</span> Spinal trigeminal nucleus

The reticular formation is a set of interconnected nuclei that are located throughout the brainstem. It is not anatomically well defined, because it includes neurons located in different parts of the brain. The neurons of the reticular formation make up a complex set of networks in the core of the brainstem that extend from the upper part of the midbrain to the lower part of the medulla oblongata. The reticular formation includes ascending pathways to the cortex in the ascending reticular activating system (ARAS) and descending pathways to the spinal cord via the reticulospinal tracts.

<span class="mw-page-title-main">Olivary body</span>

In anatomy, the olivary bodies or simply olives are a pair of prominent oval structures in the medulla oblongata, the lower portion of the brainstem. They contain the olivary nuclei.

<span class="mw-page-title-main">Pontine tegmentum</span>

The pontine tegmentum, or dorsal pons, is located within the brainstem, and is one of two parts of the pons, the other being the ventral pons or basilar part of the pons. The pontine tegmentum can be defined in contrast to the basilar pons: basilar pons contains the corticospinal tract running craniocaudally and can be considered the rostral extension of the ventral medulla oblongata; however, basilar pons is distinguished from ventral medulla oblongata in that it contains additional transverse pontine fibres that continue laterally to become the middle cerebellar peduncle. The pontine tegmentum is all the material dorsal from the basilar pons to the fourth ventricle. Along with the dorsal surface of the medulla, it forms part of the rhomboid fossa – the floor of the fourth ventricle.

<span class="mw-page-title-main">Cranial nerve nucleus</span>

A cranial nerve nucleus is a collection of neurons in the brain stem that is associated with one or more of the cranial nerves. Axons carrying information to and from the cranial nerves form a synapse first at these nuclei. Lesions occurring at these nuclei can lead to effects resembling those seen by the severing of nerve(s) they are associated with. All the nuclei except that of the trochlear nerve supply nerves of the same side of the body.

<span class="mw-page-title-main">Anterior inferior cerebellar artery</span> Major blood supply to the cerebellum

The anterior inferior cerebellar artery (AICA) is one of three pairs of arteries that supplies blood to the cerebellum.

<span class="mw-page-title-main">Facial motor nucleus</span>

The facial motor nucleus is a collection of neurons in the brainstem that belong to the facial nerve. These lower motor neurons innervate the muscles of facial expression and the stapedius.

<span class="mw-page-title-main">Cerebellar peduncle</span> Structure connecting the cerebellum to the brainstem

Cerebellar peduncles connect the cerebellum to the brain stem. There are six cerebellar peduncles in total, three on each side:

<span class="mw-page-title-main">Middle cerebellar peduncle</span> Structure in the brain connecting the pons to the cerebellum

The middle cerebellar peduncle is a paired structure of the brain. It connects the pons to the cerebellum, with fibres originating from the pontine nucleus and travelling to the opposite hemisphere of the cerebellar cortex. It is supplied by the anterior inferior cerebellar artery (AICA) and branches from the basilar artery. It conveys information from the cerebrum and the pons to the cerebellum.

The parabrachial nuclei, also known as the parabrachial complex, are a group of nuclei in the dorsolateral pons that surrounds the superior cerebellar peduncle as it enters the brainstem from the cerebellum. They are named from the Latin term for the superior cerebellar peduncle, the brachium conjunctivum. In the human brain, the expansion of the superior cerebellar peduncle expands the parabrachial nuclei, which form a thin strip of grey matter over most of the peduncle. The parabrachial nuclei are typically divided along the lines suggested by Baxter and Olszewski in humans, into a medial parabrachial nucleus and lateral parabrachial nucleus. These have in turn been subdivided into a dozen subnuclei: the superior, dorsal, ventral, internal, external and extreme lateral subnuclei; the lateral crescent and subparabrachial nucleus along the ventrolateral margin of the lateral parabrachial complex; and the medial and external medial subnuclei

References

  1. Gray, Henry (1862). Anatomy, descriptive and surgical. Blanchard and Lea. pp. 514–. Retrieved 10 November 2010.
  2. 1 2 3 4 5 6 Saladin, Kenneth S. (2007). Anatomy & physiology the unity of form and function. Dubuque, Iowa: McGraw-Hill.
  3. 1 2 3 Sinnatamby, Chummy S. (2011). Last's Anatomy (12th ed.). p. 478. ISBN   978-0-7295-3752-0.
  4. "sulcus bulbopontis". TheFreeDictionary.com. Retrieved 8 June 2023.
  5. "cerebellopontile angle". TheFreeDictionary.com. Retrieved 8 June 2023.
  6. Carpenter, M (1985). Core text of neuroanatomy (3rd ed.). Williams & Wilkins. p. 42. ISBN   0683014552.
  7. "pars basilaris pontis". TheFreeDictionary.com. Retrieved 8 June 2023.
  8. "tegmentum pontis". TheFreeDictionary.com. Retrieved 8 June 2023.
  9. Koch, Christof. "Dream States: A Peek into Consciousness". Scientific American. Scientific American. Retrieved 17 September 2020.
  10. Pritchard and Alloway Medical Neuroscience
  11. Butler and Hodos Comparative vertebrate neuroanatomy: evolution and adaptation