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The Royal Free Hospital is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Hospital, Chase Farm Hospital and a number of other sites. The trust is a founder member of the UCLPartners academic health science centre.
Emory University Hospital is a 733-bed facility in Atlanta, Georgia, specializing in the care of acutely ill adults. Emory University Hospital is staffed exclusively by Emory University School of Medicine faculty who also are members of The Emory Clinic. The hospital is renowned as one of the nation's leaders in cardiology and cardiac surgery, oncology, transplantation, ophthalmology, and the neurosciences.
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally. It kills between 25% and 90% of those infected – about 50% on average. Death is often due to shock from fluid loss, and typically occurs between six and 16 days after the first symptoms appear. Early treatment of symptoms increases the survival rate considerably compared to late start. An Ebola vaccine was approved by the US FDA in December 2019.
The 2013–2016 epidemic of Ebola virus disease, centered in Western Africa, was the most widespread outbreak of the disease in history. It caused major loss of life and socioeconomic disruption in the region, mainly in Guinea, Liberia and Sierra Leone. The first cases were recorded in Guinea in December 2013; later, the disease spread to neighbouring Liberia and Sierra Leone, with minor outbreaks occurring in Nigeria and Mali. Secondary infections of medical workers occurred in the United States and Spain. In addition, isolated cases were recorded in Senegal, the United Kingdom and Italy. The number of cases peaked in October 2014 and then began to decline gradually, following the commitment of substantial international resources.
Kent Brantly is an American doctor with the medical mission group Samaritan's Purse. While treating Ebola patients in Liberia, he contracted the virus. He became the first American to return to the United States to be treated for the disease.
An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered, it was thought that Ebola virus was not endemic to Sierra Leone or to the West African region and that the epidemic represented the first time the virus was discovered there. However, US researchers pointed to lab samples used for Lassa fever testing to suggest that Ebola had been in Sierra Leone as early as 2006.
An epidemic of Ebola virus disease occurred in Liberia from 2014 to 2015, along with the neighbouring countries of Guinea and Sierra Leone. The first cases of virus were reported by late March 2014. The Ebola virus, a biosafety level four pathogen, is an RNA virus discovered in 1976.
Four laboratory-confirmed cases of Ebola virus disease occurred in the United States in 2014. Eleven cases were reported, including these four cases and seven cases medically evacuated from other countries. The first was reported in September 2014. Nine of the people contracted the disease outside the US and traveled into the country, either as regular airline passengers or as medical evacuees; of those nine, two died. Two people contracted Ebola in the United States. Both were nurses who treated an Ebola patient; both recovered.
Thomas Eric Duncan was a Liberian citizen who became the first Ebola patient diagnosed in the United States on September 30, 2014.
This article covers the timeline of the 2014 Ebola virus epidemic in West Africa and its outbreaks elsewhere. Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths, and their first secondary transmissions, as well as relevant sessions and announcements of agencies such as the World Health Organization (WHO), the U.S. Centers for Disease Control (CDC), and NGOs such as Doctors Without Borders; medical evacuations, visa restrictions, border closures, quarantines, court rulings, and possible cases of zoonosis are also included.
Ebola virus disease in Mali occurred in October 2014, leading to concern about the possibility of an outbreak of Ebola in Mali. A child was brought from Guinea and died in the northwestern city of Kayes. Mali contact traced over 100 people who had contact with the child; tracing was completed in mid-November with no further cases discovered. In November, a second unrelated outbreak occurred in Mali's capital city, Bamako. Several people at a clinic are thought to have been infected by a man traveling from Guinea. On January 18, Mali was declared Ebola-free after 42 days with no new cases. There had been a cumulative total of eight cases with six deaths.
The Ebola virus epidemic in West Africa has had a large effect on the culture of most of the West African countries. In most instances, the effect is a rather negative one as it has disrupted many Africans’ traditional norms and practices. For instance, many West African communities rely on traditional healers and witch doctors, who use herbal remedies, massage, chant and witchcraft to cure just about any ailment. Therefore, it is difficult for West Africans to adapt to foreign medical practices. Specifically, West African resistance to Western medicine is prominent in the region, which calls for severe distrust of Western and modern medical personnel and practices.(see Ebola conspiracies below.)
Ebola virus disease in the United Kingdom and Ireland has occurred rarely in four cases to date, namely three health workers returning from treating victims of the Ebola virus epidemic in West Africa in 2014 and 2015, and a single case in 1976, when a laboratory technician contracted the disease in a needlestick injury while handling samples from Africa. All cases recovered. As of 2023, no domestic transmission of Ebola has occurred in the United Kingdom or Ireland.
Pauline Cafferkey is a Scottish nurse and aid worker who contracted Ebola virus disease in 2014 while working in Sierra Leone as part of the medical aid effort during the West African Ebola virus epidemic. She survived the illness.
Cases of the Ebola virus disease in Nigeria were reported in 2014 as a small part of the epidemic of Ebola virus disease which originated in Guinea that represented the first outbreak of the disease in a West African country. Previous outbreaks had been confined to countries in Central Africa.
There is a cure for the Ebola virus disease that is currently approved for market the US government has inventory in the Strategic National Stockpile. For past and current Ebola epidemics, treatment has been primarily supportive in nature.
Post-Ebola virus syndrome is a post-viral syndrome affecting those who have recovered from infection with Ebola. Symptoms include joint and muscle pain, eye problems, including blindness, various neurological problems, and other ailments, sometimes so severe that the person is unable to work. Although similar symptoms had been reported following previous outbreaks in the last 20 years, health professionals began using the term in 2014 when referring to a constellation of symptoms seen in people who had recovered from an acute attack of Ebola disease.
Salomé Karwah was a Liberian nurse who was named co-Person of the Year by Time magazine in 2014 for her efforts to combat the West African Ebola virus epidemic. She appeared on the cover of Time in December 2014 with other health care workers and colleagues working to end the epidemic. Karwah survived ebola herself, before returning to work with Médecins Sans Frontières to help other patients afflicted with the disease. The actions of Karwah and other health care professionals are believed to have saved lives of thousands. However, two years later, Karwah died from complications of childbirth; her widower suggested that this might have been due to the widespread, mistaken belief that ebola survivors can still transmit the virus. Even before the ebola outbreak, Liberia had one of the highest rates of maternal mortality in the world.
Colleen S. Kraft is an infectious disease physician, associate professor in the Department of Pathology and Laboratory Medicine, and the director of the Clinical Virology Research Laboratory at Emory University School of Medicine. In 2014, she led Emory University Hospital's effort to treat and care for Ebola virus disease patients and is currently working to address the COVID-19 pandemic in Georgia. She currently serves on Georgia's COVID-19 task force.
John J. Lowe is an American infectious disease scientist, assistant vice chancellor for health security at University of Nebraska Medical Center, and associate professor in the Department of Environmental, Agricultural and Occupational Health at University of Nebraska Medical Center College of Public Health. In 2014, he led Nebraska Medicine hospital’s effort to treat and care for Ebola virus disease patients and led the University of Nebraska Medical Center’s coronavirus disease 2019 response efforts.
References
- 1 2 "Ebola found in doctor's eye months after virus left his blood". USA Today. Associated Press. 8 May 2015. Retrieved 8 May 2015.
- 1 2 3 "The Long, Extraordinary Recovery of Ian Crozier". Emory Medicine Magazine.
- 1 2 3 4 Grady, Denise (8 December 2014). "An Ebola Doctor's Return From the Edge of Death". New York Times. Retrieved 8 May 2015.
- 1 2 Humphrey, Nancy (Winter 2015). "The Long Road Back". Vanderbilt Medicine Magazine. Retrieved 8 May 2015.
- ↑ O'Carroll, Lisa (8 December 2014). "Ebola survivor Ian Crozier: 'Everyone thought he was going to die'". The Guardian. Retrieved 8 May 2015.
- ↑ Raab, Lauren (8 December 2014). "With Ian Crozier's reveal, here are the 10 Ebola patients treated in U.S." Los Angeles Times. Retrieved 8 May 2015.
