A cyclotron is a type of particle accelerator invented by Ernest Lawrence in 1929–1930 at the University of California, Berkeley, and patented in 1932. A cyclotron accelerates charged particles outwards from the center of a flat cylindrical vacuum chamber along a spiral path. The particles are held to a spiral trajectory by a static magnetic field and accelerated by a rapidly varying electric field. Lawrence was awarded the 1939 Nobel Prize in Physics for this invention.
A synchrocyclotron is a special type of cyclotron, patented by Edwin McMillan in 1952, in which the frequency of the driving RF electric field is varied to compensate for relativistic effects as the particles' velocity begins to approach the speed of light. This is in contrast to the classical cyclotron, where this frequency is constant.
A synchrotron is a particular type of cyclic particle accelerator, descended from the cyclotron, in which the accelerating particle beam travels around a fixed closed-loop path. The magnetic field which bends the particle beam into its closed path increases with time during the accelerating process, being synchronized to the increasing kinetic energy of the particles. The synchrotron is one of the first accelerator concepts to enable the construction of large-scale facilities, since bending, beam focusing and acceleration can be separated into different components. The most powerful modern particle accelerators use versions of the synchrotron design. The largest synchrotron-type accelerator, also the largest particle accelerator in the world, is the 27-kilometre-circumference (17 mi) Large Hadron Collider (LHC) near Geneva, Switzerland, built in 2008 by the European Organization for Nuclear Research (CERN). It can accelerate beams of protons to an energy of 13 tera electronvolts (TeV or 1012 eV).
TRIUMF is Canada's national particle accelerator centre. It is considered Canada's premier physics laboratory, and consistently regarded as one of the world's leading subatomic physics research centres. Owned and operated by a consortium of universities, it is on the south campus of one of its founding members, the University of British Columbia in Vancouver, British Columbia, Canada. It houses the world's largest normal conducting cyclotron, a source of 520 MeV protons, which was named an IEEE Milestone in 2010. Its accelerator-focused activities involve particle physics, nuclear physics, nuclear medicine, materials science, and detector and accelerator development.
A charged particle beam is a spatially localized group of electrically charged particles that have approximately the same position, kinetic energy, and direction. The kinetic energies of the particles are much larger than the energies of particles at ambient temperature. The high energy and directionality of charged particle beams make them useful for many applications in particle physics.
The Paul Scherrer Institute (PSI) is a multi-disciplinary research institute for natural and engineering sciences in Switzerland. It is located in the Canton of Aargau in the municipalities Villigen and Würenlingen on either side of the River Aare, and covers an area over 35 hectares in size. Like ETH Zurich and EPFL, PSI belongs to the Swiss Federal Institutes of Technology Domain of the Swiss Confederation. The PSI employs around 2,100 people. It conducts basic and applied research in the fields of matter and materials, human health, and energy and the environment. About 37% of PSI's research activities focus on material sciences, 24% on life sciences, 19% on general energy, 11% on nuclear energy and safety, and 9% on particle physics.
In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy nearby tissues.
A particle-beam weapon uses a high-energy beam of atomic or subatomic particles to damage the target by disrupting its atomic and/or molecular structure. A particle-beam weapon is a type of directed-energy weapon, which directs energy in a particular and focused direction using particles with minuscule mass. Some particle-beam weapons have potential practical applications, e.g. as an antiballistic missile defense system. They have been known by myriad names: particle accelerator guns, ion cannons, proton beams, lightning rays, rayguns, etc.
The Bragg peak is a pronounced peak on the Bragg curve which plots the energy loss of ionizing radiation during its travel through matter. For protons, α-rays, and other ion rays, the peak occurs immediately before the particles come to rest. It is named after William Henry Bragg, who discovered it in 1903.
Fast neutron therapy utilizes high energy neutrons typically between 50 and 70 MeV to treat cancer. Most fast neutron therapy beams are produced by reactors, cyclotrons (d+Be) and linear accelerators. Neutron therapy is currently available in Germany, Russia, South Africa and the United States. In the United States, one treatment center is operational, in Seattle, Washington. The Seattle center uses a cyclotron which produces a proton beam impinging upon a beryllium target.
Particle therapy is a form of external beam radiotherapy using beams of energetic neutrons, protons, or other heavier positive ions for cancer treatment. The most common type of particle therapy as of August 2021 is proton therapy.
A particle accelerator is a machine that uses electromagnetic fields to propel charged particles to very high speeds and energies, and to contain them in well-defined beams.
The Harvard Cyclotron Laboratory operated from 1949 to 2002. It was most notable for its contributions to the development of proton therapy.
A Fixed-Field alternating gradient Accelerator is a circular particle accelerator concept that can be characterized by its time-independent magnetic fields and the use of alternating gradient strong focusing.
A dielectric wall accelerator (DWA) is a compact linear particle accelerator concept designed and patented in the late 1990s, that works by inducing a travelling electromagnetic wave in a tube which is constructed mostly from a dielectric material. The main conceptual difference to a conventional disk-loaded linac system is given by the additional dielectric wall and the coupler construction.
The Indiana University Health Proton Therapy Center, formerly known as the Midwest Proton Radiotherapy Institute (MPRI), was the first proton facility in the Midwest. The center was located on the Indiana University campus in Bloomington, Indiana, United States. The IU Health Proton Therapy Center was the only proton therapy center in the U.S. to use a uniform-scanning beam for dose delivery, which decreases undesirable neutron dose to patients. The Center opened in 2004, and ceased operations in 2014.
The Sarayköy Nuclear Research and Training Center, known as SANAEM, is a nuclear research and training center of Turkey. The organization was established on July 1, 2005, as a subunit of Turkish Atomic Energy Administration at Kazan district in northwest of Ankara on an area of 42.3 ha.
The The Svedberg Laboratory (TSL) is a university facility, based in Uppsala, Sweden. The activities at TSL are based around the particle accelerator Gustaf Werner cyclotron.
Rutherford Health was a private oncology provider founded by Mike Moran and Karol Sikora in 2015, with investment from Neil Woodford and the Wales Life Sciences Investment Fund, to develop proton therapy facilities in the United Kingdom and elsewhere. Until 2019 it was known as Proton Partners International.
The Louvain-la-Neuve Cyclotron is a brutalist architectural complex of the University of Louvain built from 1970 to 1972 in Louvain-la-Neuve, Walloon Brabant, Belgium, notably holding UCLouvain's CYCLONE particle accelerators. It is the first building completed by the university when it moved following the Leuven crisis and was the largest cyclotron in Europe at the time of its construction. The Louvain Cyclotron can also refer to Belgium's first cyclotron built in Louvain (Leuven) in 1947, which was replaced by the Louvain-la-Neuve center.
