Israel Institute for Biological Research

Last updated

Israel Institute for Biological Research (IIBR) is an Israeli research and development laboratory [1] It is under the jurisdiction of the Prime Minister's Office [2] that works in close cooperation with Israeli government agencies. IIBR has many public projects on which it works with international research organizations (governmental and non-governmental) and universities. It has approximately 350 employees, 150 of whom are scientists. Its research findings are often published in national and international scientific publications. [1] It is widely believed to be involved in the manufacturing of biological and chemical weapons. [3] The IIBR is currently developing a COVID-19 vaccine Brilife. [4]

Contents

History

IIBR originated with Hemed Bet, the Haganah biological warfare unit, which Alexander Kenyan, then a microbiology student, established in Jaffa in February 1948, shortly before Israeli independence, at the direction of Yigael Yadin, the Haganah's chief operations officer. Ephraim Katzir was Hemed Bet's first commander. [3]

The institute in its current form was founded in 1952, [1] after Hemed Bet relocated to an orange grove near Ness Ziona. [3] It was founded partly in a former Palestinian mansion of Wadi Hunayn. [5] [6] Among the founders were Professor Ernst David Bergmann, Prime Minister David Ben-Gurion's science adviser and the head of R&D at the Ministry of Defense. Keynan was IIBR's first director. [1]

Some of the fields in which IIBR conducts research include:

The institute is widely suspected of being involved in developing chemical and biological weapons. It is also assumed that the Institute develops vaccines and antidotes for such weapons. While refusing to confirm it, Israel is widely suspected of having developed offensive biological and chemical weapons capabilities, and the Israeli intelligence service Mossad is known to have used biological weapons in assassination missions. Israel has not signed the Biological Weapons Convention and has signed but not ratified the Chemical Weapons Convention. [3]

Marcus Klingberg, the highest-ranking spy for the Soviet Union ever caught in Israel, served as the IIBR's Deputy Scientific Director. He had joined the IIBR in 1957 and served as Deputy Scientific Director until 1972 as well as Head of the Department of Epidemiology until 1978. He was arrested in 1983 and convicted of espionage. His arrest and sentencing was kept a secret for over a decade. [2]

El Al Flight 1862, which crashed in the Netherlands in 1992, was carrying cargo destined for the Israel Institute for Biological Research which included 190 litres of dimethyl methylphosphonate, which (among many other uses) could be used in the synthesis of Sarin nerve gas, and is now a Chemical Weapons Convention schedule 2 chemical. Israel stated that the material was non-toxic, was to have been used to test filters that protect against chemical weapons, and that it had been listed on the cargo manifest in accordance with international regulations. The Dutch foreign ministry confirmed that it had already known about the presence of chemicals on the aircraft. [7] [8] According to the chemical weapons site CWInfo the quantity involved was "too small for the preparation of a militarily useful quantity of Sarin, but would be consistent with making small quantities for testing detection methods and protective clothing". [9]

According to British intelligence writer Gordon Thomas, the facility is surrounded by a high concrete wall topped with sensors, and armed guards patrol its perimeter. No aircraft are allowed to overfly the facility, and it does not appear on any map or telephone directory of the area. Inside the facility, code words and visual identification control access to each area, and there are numerous bombproof sliding doors that can only be opened by swipe cards whose codes are changed every day. Corridors inside the facility are patrolled by guards. Many of the research facilities are deep underground. All employees and their families undergo intense health checks every month. [10]

Life Science Research Israel

Life Science Research Israel (LSRI), a subsidiary of IIBR, is dedicated to the commercial exploitation of innovative technologies developed by IIBR. According to its 2000 annual report, the 2000 budget was 16.6 million NIS (about US$4 million), with revenues of 12.9 million NIS (US$3 million). [11]

See also

Related Research Articles

<span class="mw-page-title-main">Chemical warfare</span> Using poison gas or other toxins in war

Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons. This type of warfare is distinct from nuclear warfare, biological warfare and radiological warfare, which together make up CBRN, the military acronym for chemical, biological, radiological, and nuclear, all of which are considered "weapons of mass destruction" (WMDs), a term that contrasts with conventional weapons.

<span class="mw-page-title-main">Sarin</span> Chemical compound and chemical warfare nerve agent

Sarin is an extremely toxic synthetic organophosphorus compound. A colourless, odourless liquid, it is used as a chemical weapon due to its extreme potency as a nerve agent. Exposure is lethal even at very low concentrations, where death can occur within one to ten minutes after direct inhalation of a lethal dose, due to suffocation from respiratory paralysis, unless antidotes are quickly administered. People who absorb a non-lethal dose and do not receive immediate medical treatment may suffer permanent neurological damage.

<span class="mw-page-title-main">Tabun (nerve agent)</span> Chemical compound

Tabun or GA is an extremely toxic synthetic organophosphorus compound. It is a clear, colorless, and tasteless liquid with a faint fruity odor. It is classified as a nerve agent because it fatally interferes with normal functioning of the mammalian nervous system. Its production is strictly controlled and stockpiling outlawed by the Chemical Weapons Convention of 1993. Tabun is the first of the G-series nerve agents along with GB (sarin), GD (soman) and GF (cyclosarin).

<span class="mw-page-title-main">Soman</span> Chemical compound (nerve agent)

Soman is an extremely toxic chemical substance. It is a nerve agent, interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase. It is an inhibitor of both acetylcholinesterase and butyrylcholinesterase. As a chemical weapon, it is classified as a weapon of mass destruction by the United Nations according to UN Resolution 687. Its production is strictly controlled, and stockpiling is outlawed by the Chemical Weapons Convention of 1993 where it is classified as a Schedule 1 substance. Soman was the third of the so-called G-series nerve agents to be discovered along with GA (tabun), GB (sarin), and GF (cyclosarin).

<span class="mw-page-title-main">VX (nerve agent)</span> Chemical compound and chemical warfare nerve agent

VX is an extremely toxic synthetic chemical compound in the organophosphorus class, specifically, a thiophosphonate. In the class of nerve agents, it was developed for military use in chemical warfare after translation of earlier discoveries of organophosphate toxicity in pesticide research. In recent years, VX was found to be the agent used in the assassination of Kim Jong-nam. In its pure form, VX is an oily, relatively non-volatile liquid that is amber-like in colour. Because of its low volatility, VX persists in environments where it is dispersed.

<span class="mw-page-title-main">Porton Down</span> Military science park in Wiltshire, England

Porton Down is a science park in Wiltshire, England, just northeast of the village of Porton, near Salisbury. It is home to two British government facilities: a site of the Ministry of Defence's Defence Science and Technology Laboratory (Dstl) – known for over 100 years as one of the UK's most secretive and controversial military research facilities, occupying 7,000 acres (2,800 ha) – and a site of the UK Health Security Agency. It is also home to other private and commercial science organisations, and is expanding to attract other companies.

<span class="mw-page-title-main">Israel and weapons of mass destruction</span>

Israel is widely believed to possess weapons of mass destruction, and to be one of four nuclear-armed countries not recognized as a Nuclear Weapons State by the Non-Proliferation Treaty (NPT). The US Congress Office of Technology Assessment has recorded Israel as a country generally reported as having undeclared chemical warfare capabilities, and an offensive biological warfare program. Officially, Israel neither confirms nor denies possessing nuclear weapons.

Cyclosarin or GF is an extremely toxic substance used as a chemical weapon. It is a member of the G-series family of nerve agents, a group of chemical weapons discovered and synthesized by a German team led by Dr. Gerhard Schrader. The major nerve gases are the G agents, sarin (GB), soman (GD), tabun (GA), and the V agents such as VX. The original agent, tabun, was discovered in Germany in 1936 in the process of work on organophosphorus insecticides. Next came sarin, soman and finally, cyclosarin, a product of commercial insecticide laboratories prior to World War II.

<span class="mw-page-title-main">VG (nerve agent)</span> Chemical compound

VG is a "V-series" nerve agent chemically similar to the better-known VX nerve agent. Tetram is the common Russian name for the substance. Amiton was the trade name for the substance when it was marketed as an insecticide by ICI in the mid-1950s.

<span class="mw-page-title-main">Chemical weapon proliferation</span> Prevalence and spread of chemical weapons

Many nations continue to research and/or stockpile chemical weapon agents despite numerous efforts to reduce or eliminate them. Most states have joined the Chemical Weapons Convention (CWC), which required the destruction of all chemical weapons by 2012. Twelve nations have declared chemical weapons production facilities and six nations have declared stockpiles of chemical weapons. All of the declared production facilities have been destroyed or converted to civilian use after the treaty went into force.

<span class="mw-page-title-main">Dimethyl methylphosphonate</span> Chemical compound

Dimethyl methylphosphonate is an organophosphorus compound with the chemical formula CH3PO(OCH3)2. It is a colourless liquid, which is primarily used as a flame retardant.

<span class="mw-page-title-main">Iraqi chemical weapons program</span> Offensively and genocidally used chemical weapons

In violation of the Geneva Protocol of 1925, the Iraqi Army initiated two failed and one successful (1978–1991) offensive chemical weapons (CW) programs. President Saddam Hussein (1937–2006) pursued the most extensive chemical program during the Iran–Iraq War (1980–1988), when he waged chemical warfare against his foe. He also used chemicals in 1988 in the Al-Anfal Campaign against his civilian Kurdish population and during a popular uprising in the south in 1991.

<span class="mw-page-title-main">Libya and weapons of mass destruction</span>

Libya pursued programs to develop or acquire weapons of mass destruction from when Muammar Gaddafi seized control of Libya in 1969 until he announced on 19 December 2003 that Libya would voluntarily eliminate all materials, equipment and programs that could lead to internationally proscribed weapons. This included weapons of mass destruction and long-range ballistic missiles.

<span class="mw-page-title-main">El Al Flight 1862</span> 1992 plane crash in the Netherlands

On 4 October 1992, El Al Flight 1862, a Boeing 747 cargo aircraft of the then state-owned Israeli airline El Al, crashed into the Groeneveen and Klein-Kruitberg flats in the Bijlmermeer neighbourhood of Amsterdam, the Netherlands. The crash is known in Dutch as the Bijlmerramp.

<span class="mw-page-title-main">Chemical weapon</span> Device that uses chemicals to kill or harm individuals

A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action. Munitions or other delivery devices designed to deliver chemical weapons, whether filled or unfilled, are also considered weapons themselves."

The Scientific Studies and Research Center (SSRC), better known by its French name Centre D'Etudes et de Recherches Scientifiques (CERS), is a Syrian government agency that has the goal of advancing and coordinating scientific activities in the country. It works on research and development for the economic and social development of Syria, especially the computerization of government agencies. It is considered to have better technical capacity and equipment than the Syrian universities. Jane's Information Group Intelligence Services and other analysts believe it is responsible for research and development of nuclear, biological, chemical and missile technology and weapons, including ballistic missiles, as well as advanced conventional arms.

The United States chemical weapons program began in 1917 during World War I with the creation of the U.S. Army's Gas Service Section and ended 73 years later in 1990 with the country's practical adoption of the Chemical Weapons Convention. Destruction of stockpiled chemical weapons began in 1985 and is still ongoing. The U.S. Army Medical Research Institute of Chemical Defense (USAMRICD), at Aberdeen Proving Ground, Maryland, continues to operate.

Chemical weapons have been a part of warfare in most societies, although their use has been particularly controversial since the 20th century.

<span class="mw-page-title-main">BriLife</span> Vaccine candidate against COVID-19

BriLife, also known as IIBR-100, is a replication-competent recombinant VSV viral vectored COVID-19 vaccine candidate. It was developed by the Israel Institute for Biological Research (IIBR). The IIBR partnered with the US-based NRx Pharmaceuticals to complete clinical trials and commercialize the vaccine. A study conducted in hamsters suggested that one dose of the vaccine was safe and effective at protecting against COVID-19.

References

  1. 1 2 3 4 IIBR website
  2. 1 2 Ostrovsky, Victor (December 1998). "Crash of Cargo Plane in Holland Revealed Existence of Israeli Chemical and Biological Weapons Plant". Washington Report on Middle East Affairs: 19–20.
  3. 1 2 3 4 Ginsburg, Mitch. "'Should there be a need': The inside story of Israel's chemical and biological arsenal". www.timesofisrael.com. Retrieved 2020-05-07.
  4. "Israel names its vaccine candidate: Brilife - The Jerusalem Post". Archived from the original on 2020-10-19.
  5. Khalidi, Walid (1992). All That Remains: The Palestinian Villages Occupied and Depopulated by Israel in 1948. Washington D.C.: Institute for Palestine Studies. p. 421. ISBN   0-88728-224-5.
  6. Traces of poison, Salman Abu-Sitta, 5 March 2003, Al-Ahram
  7. "Israel says El Al crash chemical 'non-toxic'". BBC. October 2, 1998. Archived from the original on 18 August 2003. Retrieved 2 July 2006.
  8. Greenberg, Joel (2 October 1998). "Nerve-Gas Element Was in El Al Plane Lost in 1992 Crash". New York Times. Retrieved 11 October 2007.
  9. "Nerve Agent Precursor: Dimethyl Methyl Phosphonate". cbwinfo.com. 4 September 2013. Archived from the original on 4 September 2013.
  10. Thomas, Gordon: Gideon's Spies: The secret history of the Mossad (1999)
  11. מ"עב םייחה יעדמ רקחל תילארשיה הרבחה (in Hebrew)

Coordinates: 31°55′28.85″N34°47′29.97″E / 31.9246806°N 34.7916583°E / 31.9246806; 34.7916583