Itzhak Brook (1941 - January 10, 2025) was an Israeli-American physician and medical researcher.
Itzhak Brook was born in Afula in present-day Israel during the British Mandate era and raised in Haifa. His parents, Bernard (Baruch) and Chaya Brook, were immigrants from Austria and Poland respectively. His mother was a seamstress and his father was a welder and professional soccer player for Hapoel Haifa F.C. He had a younger sister, Zipi, who he cared for after his parents' deaths. [1]
Brook graduated from the Hareali Haivri high school and was drafted into the Israel Defense Forces in 1959 and completed an officer's course. He studied medicine at the Hebrew University of Jerusalem's Hadassah School of Medicine, earning an MD in 1968 and subsequently completing his residency there, and obtained an MSc in pediatrics from Tel Aviv University in 1972. He served as a medic in the Israeli army during the Six-Day War in 1967 and subsequently as a Lieutenant battalion physician during the Yom Kippur War in 1973. After crossing the Suez Canal in his ambulance he was severely wounded by artillery fire. [1] In 1974, Brook moved to the United States with his family. He completed a fellowship in infectious diseases at the University of California, Los Angeles and served in the United States Navy Medical Corps for 27 years. [2] [3]
Brook was also an adjunct professor of pediatrics and medicine at Georgetown University School of Medicine in Washington, D.C., specializing in infectious diseases. He served as chairman of the Anti-infective Drug Advisory Committee of the Food and Drug Administration (FDA) [4] and chaired the Committee when AZT was approved for the treatment of HIV/AIDS in 1987. [5]
Brook has developed treatment guidelines for primary care clinicians, [6] and has also done work on infectious disease of broad public interest. His main research interests are anaerobic infections, sinusitis, and tonsillitis. He is a long-standing campaigner against overuse of antibiotics which can lead to antibiotic resistance, [7] has researched common health threats like disease transmission on airplanes, [8] while dispelling common concerns about contaminated library books and subway handlebars. [9] [10] He has also been an expert source for major media on health issues like AZT, [11] improving patient care after his own serious illness and cancer, [12] [13] [14] and preventing medical errors. [15]
Brook authored publications in scientific journals and 10 medical textbooks. [16] [17] [18] He is the author of "The Laryngectomee Guide" that was published in 22 languages. [19]
He was the US editor of Journal of Pediatric Infectious Diseases, [20] Editor Textbook of "Pediatrics Infectious Diseases " at Medscape Reference, [21] Section Editor of "Pediatric Infections" at Current Infectious Diseases Report, [22] associate editor of Journal of Medical Case Reports , [23] a member of the editorial board of several medical journals, and a board member of the Head and Neck Cancer Alliance . [24]
During his service in the United States Navy he researched the treatment of bacterial infections after ionized radiation [25] for which he was awarded three Defense Meritorious Service Medals. Brook received the 2012 J. Conley Medical Ethics Award of the American Academy of Otolaryngology–Head and Neck Surgery. [26]
Brook was a fellow of the Infectious Diseases Society of America, the Society for Pediatric Research, and the Pediatric Infectious Diseases Society.[ citation needed ] His research interests included anaerobic infections, the pathogenesis and therapy of polymicrobial infections, including upper respiratory tract infections (i.e. sinusitis, tonsillitis).
At age 65, Brook was diagnosed with throat cancer and underwent a laryngectomy. [1] He wrote a book about that experience [27] [28] and a book about his experiences as a battalion physician in the 1973 Yom Kippur War. [29] [30]
Brook married Zahava Goldwasser in 1966. They had two children in Israel, Dafna and Danny, and a third child, Tammy, in the United States. (Tammy is the founder and CEO of FYI Brand Group. [31] ) The marriage later ended in divorce. He subsequently married Joyce Reback in 1981 and they had two children, Yoni and Sara. Brook died of cancer on January 10, 2025 at the age of 83. He was survived by his wife Joyce, five children, five grandchildren, and sister. [1]