James Adjaye

Last updated
Prof.
James Adjaye
Born
James Affram Adjaye

(1964-11-11) 11 November 1964 (age 60)
Accra, Ghana
Nationality Ghanaian British
Education
Alma mater
Occupations Academic
Scientific career
Fields
Institutions
Relatives

James Affram Adjaye is a Ghanaian British stem cell researcher. He is the Director of the Institute for Stem Cell Research and Regenerative Medicine at the Heinrich Heine University's faculty of medicine. [1] [2] [3] He also leads the Molecular Embryology and Aging Group of the Max Planck Institute for Molecular Genetics situated in Berlin, Germany. [2] [4] [5] Adjaye has contributed to multiple research publications on induced pluripotent stem cells (iPSCs).

Contents

Early life and education

Adjaye had his secondary at the Accra Academy in Ghana, and John Kelly Boys High School in the United Kingdom. He proceeded to the University College of Cardiff where he obtained his Bachelor of Science degree in biochemistry in 1987. [2] He then enrolled at the University of Sussex a year later for further studies in Biochemistry, there, he was awarded his Master of Science degree in biochemistry in 1989 under the supervision of Dr. Felicity Watts. [6] For his doctorate degree, Adjaye enrolled at the King's College, London for his research in genetic manipulation and molecular biology spanning from 1989 to 1992. [2] Adjaye's thesis was on cDNA cloning and immunological properties of a squid neurofilament gene homologue. [7] Adjaye then joined the Max Planck Institute of Biophysical Chemistry in Goettingen, Germany in 1992 as a postdoctoral fellow. He worked in that capacity until 1995. In 1996, he had another postdoctoral fellowship at the Institute of Child Health, University College of London and remained there until 2001. [5] [4]

Career

Max Planck Institute for Biology in Tubingen, Germany Max Planck Institute for Biology 2022.jpg
Max Planck Institute for Biology in Tübingen, Germany

A year after his postdoctoral fellowship at the Institute of Child Health, University College of London, Adjaye joined the Max Planck Institute of Molecular Genetics in Berlin as the group leader of the Molecular Embryology and Aging Group. [8] [9] He has worked in this capacity to date. In 2012, he became a professor at the Heinrich Heine University Düsseldorf. [10] There, he is director of the Institute for Stem Cell Research and Regenerative Medicine of the university's Faculty of Medicine. He is the also the Chairs of Stem Cell Research and Regenerative Medicine. [5] [4] [10]

Research work and selected publications

Both nationally and internationally, Adjaye's research takes a systems biology approach. Using iPSCs he models brain, liver, and kidney associated diseases such as Nijmegen Breakage Syndrome, Bilirubin-induced neuronal damage, Alzheimer's disease, and non-alcoholic fatty liver disease. [4] [10] [11]

His works have been featured in journals such as the International Journal of Molecular Sciences , EMBO Reports , Stem Cell Research , Cell Reports , the Journal of Alzheimer's Disease , [4] and BMC Genomics .

Some of his works include:

Personal life

Prof. James Adjaye is married to Mrs. Theresa Adjaye who is by profession a Clinical Pharmacist/ Independent Prescriber specialising in cardiovascular disease.[ citation needed ] Together, they have 4 children.[ citation needed ]

He is the elder brother of the British architect Sir. David Adjaye and musician Peter Adjaye. [12]

References

  1. ↑ "Molecular Embryology and Aging Group (James Adjaye)". www.molgen.mpg.de. Retrieved 2022-03-07.
  2. 1 2 3 4 "James Adjaye, Chair of Stem Cell Research, Heinrich Heine University". Drug Target Review. Retrieved 2022-03-07.
  3. ↑ Brand-Saberi, Beate (2020-01-03). Essential Current Concepts in Stem Cell Biology. Springer Nature. ISBN   978-3-030-33923-4.
  4. 1 2 3 4 5 6 "James Adjaye, PhD | Journal of Alzheimer's Disease". www.j-alz.com. Retrieved 2022-03-07.
  5. 1 2 3 "Institut für Stammzellforschung und Regenerative Medizin". UKD (in German). Retrieved 2022-03-07.[ permanent dead link ]
  6. ↑ "University College London". profiles.ucl.ac.uk. Retrieved 2025-03-12.
  7. ↑ Adjaye, J.; Marsh, P. J.; Eagles, P. A. (December 1993). "Immunological properties and cDNA sequence analysis of an intermediate-filament-like protein from squid neuronal tissue". Journal of Cell Science. 106 ( Pt 4): 1283–1290. doi:10.1242/jcs.106.4.1283. ISSN   0021-9533. PMID   8126107.
  8. ↑ Methods in Systems Biology. Academic Press. 2011-09-19. ISBN   978-0-12-385119-2.
  9. ↑ Thornhill, Alan (2007). Single Cell Diagnostics: Methods and Protocols. Springer Science & Business Media. ISBN   978-1-59745-298-4.
  10. 1 2 3 Andriani, Daskalaki (2012-11-30). Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications: Clinical Tools and Applications. IGI Global. ISBN   978-1-4666-2507-5.
  11. 1 2 "Universität Düsseldorf: James Adjaye". www.neurosciences-duesseldorf.de. Retrieved 2022-03-07.
  12. ↑ "Dirty house music: how David Adjaye's DJ brother turns his buildings into beats". the Guardian. 2016-07-14. Retrieved 2022-07-26.
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