Jane Mitchell is a professor of pharmacology in clinical care medicine at Imperial College London. [1] Her research focusses on the regulation of cardiovascular health and disease, with a particular interest in endothelial cells, prostacyclin (a platelet activator and vasodilator), and nitric oxide. [2]
She finished her PhD with Nobel Laureate John Vane and worked as a postdoctoral fellow with another Nobel Laureate: Ferid Murad. She became a professor when she was 38. [2] Mitchell won the Novartis Prize for Pharmacology in 1999 for her work on cyclooxygeanse biology. [1] In 2012, she won the AstraZeneca Prize for Women in Pharmacology. [3]
Mitchell grew up in a coal mining town. People around her frequently died young from cardiovascular and respiratory diseases, which inspired her to pursue a career in clinical research, with a focus on hearts and lungs. [2] She studied biological sciences at Lancaster University. [2]
Gerty Theresa Cori was a Bohemian-Austrian and American biochemist who in 1947 was the third woman to win a Nobel Prize in science, and the first woman to be awarded the Nobel Prize in Physiology or Medicine, for her role in the "discovery of the course of the catalytic conversion of glycogen".
Ferid Murad was an American physician and pharmacologist, and a co-winner of the 1998 Nobel Prize in Physiology or Medicine.
Sir James Whyte Black was a Scottish physician and pharmacologist. Together with Gertrude B. Elion and George H. Hitchings, he shared the Nobel Prize for Medicine in 1988 for pioneering strategies for rational drug-design, which, in his case, led to the development of propranolol and cimetidine. Black established a Veterinary Physiology department at the University of Glasgow, where he became interested in the effects of adrenaline on the human heart. He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment of heart disease. Black was also responsible for the development of cimetidine, an H2 receptor antagonist, a drug used to treat stomach ulcers.
Robert Francis Furchgott was a Nobel Prize-winning American biochemist who contributed to the discovery of nitric oxide as a transient cellular signal in mammalian systems.
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy.
Rosalyn Sussman Yalow was an American medical physicist, and a co-winner of the 1977 Nobel Prize in Physiology or Medicine for development of the radioimmunoassay technique. She was the second woman, and the first American-born woman, to be awarded the Nobel Prize in Physiology or Medicine.
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889.
Imperial College School of Medicine (ICSM) is the undergraduate medical school of Imperial College London in England and one of the United Hospitals. It is part of the college's Faculty of Medicine and was formed by the merger of several historic medical schools. Its core campuses are located at South Kensington, St Mary's, Charing Cross, Hammersmith and Chelsea and Westminster. The school ranked 3rd in the world for medicine in the 2022 Times Higher Education World University Rankings.
The University of Virginia School of Medicine is the graduate medical school of the University of Virginia. The school's facilities are on the University of Virginia grounds adjacent to Academical Village in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, UVA SoM is the tenth oldest medical school in the United States. The School of Medicine confers Doctor of Medicine (M.D.) and Doctor of Philosophy (PhD) degrees, and is closely associated with both the University of Virginia Health System and Inova Health System.
Carolyn Ruth Bertozzi is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology. She coined the term "bioorthogonal chemistry" for chemical reactions compatible with living systems. Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer, inflammation, and viral infections like COVID-19. At Stanford University, she holds the Anne T. and Robert M. Bass Professorship in the School of Humanities and Sciences. Bertozzi is also an Investigator at the Howard Hughes Medical Institute (HHMI) and is the former director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory.
Robert Joseph Lefkowitz is an American physician and biochemist. He is best known for his discoveries that reveal the inner workings of an important family of G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University.
Case Western Reserve University School of Medicine is the medical school of Case Western Reserve University, a private research university in Cleveland, Ohio. It is the largest biomedical research center in Ohio. CWRU SOM is primarily affiliated with University Hospitals Cleveland Medical Center, Cleveland Clinic, and the MetroHealth System.
Stefanie Dimmeler is a German biologist specializing in the pathophysiological processes underlying cardiovascular diseases. Her awards and honours include the Gottfried Wilhelm Leibniz Prize of the German Research Foundation for her work on the programmed cell death of endothelial cells. Since 2008 she has led the Institute for Cardiovascular Regeneration at the University of Frankfurt. Her current work is focusing to develop cellular and pharmacological strategies to improve cardiovascular repair and regeneration. Her work aims to establish non-coding RNAs as novel therapeutic targets.
Tu Youyou is a Chinese malariologist and pharmaceutical chemist. She discovered artemisinin and dihydroartemisinin, used to treat malaria, a breakthrough in twentieth-century tropical medicine, saving millions of lives in South China, Southeast Asia, Africa, and South America.
Ada E. Yonath is an Israeli crystallographer and Nobel laureate in Chemistry, best known for her pioneering work on the structure of ribosomes. She is the current director of the Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly of the Weizmann Institute of Science.
The Massry Prize was established in 1996, and was administered by the Meira and Shaul G. Massry Foundation until 2019. The Prize, of $40,000 and the Massry Lectureship, is bestowed upon scientists who have made substantial recent contributions in the biomedical sciences. Shaul G. Massry, M.D., who established the Massry Foundation, is Professor Emeritus of Medicine and Physiology and Biophysics at the Keck School of Medicine, University of Southern California. He served as Chief of its Division of Nephrology from 1974 to 2000. In 2009 the KECK School of Medicine was asked to administer the Prize, and has done so since that time. Ten winners of the Massry Prize have gone on to be awarded a Nobel Prize.
Garret Adare FitzGerald is an Irish physician. He is professor of translational medicine and therapeutics and chair of the department of pharmacology at the Perelman School of Medicine of the University of Pennsylvania. He researches aspects of cardiology, pharmacology, translational medicine, and chronobiology.
Emma Harriet Baker is a British professor of clinical pharmacology and consultant physician in internal medicine at St George's Hospital, London. She has a specialist interest in people who have multiple medical conditions at the same time and take several medications, with a particular focus on lung disease. She is director of the UK's first BSc in clinical pharmacology, clinical vice president of the British Pharmacological Society and training programme director at Health Education England.
Robert Michael Graham AO, FAA, FAHMS is an Australian-born clinician-scientist. He is the Des Renford Professor of Medicine at University of New South Wales and the Head of the Molecular Cardiology and Biophysics Division at Victor Chang Cardiac Research Institute.
Amrita Ahluwalia is a British pharmacologist and professor of vascular pharmacology at Queen Mary University of London. Her research considers the development of therapeutics for cardiovascular inflammation. She was awarded the WISE Research Award in 2015.