Jean Elise Schaffer is an American physician-scientist. She is a Senior Investigator at the Joslin Diabetes Center,[1] where she also serves as an Associate Research Director, and she is a Professor of Medicine at Harvard Medical School.[2] Her work focuses on fundamental mechanisms of metabolic stress responses and the pathophysiology of diabetes complications.
In 1995, Schaffer joined the faculty at Washington University School of Medicine in St Louis. She rose through the ranks and was appointed as the inaugural Virginia Minnich Distinguished Professor of Medicine.[6] In addition to leading a laboratory focused on metabolic disease research, she directed the NIDDK-funded Diabetes Research Center at Washington University from 2008-2019. Her laboratory discovered that disruption of specific small nucleolar RNAs protects against lipid-induced cell death and alters metabolism, work that has provided a new understanding of how nutrient signals influence cellular homeostasis through non-coding RNAs.[7] Schaffer’s contributions to the fields of lipid metabolism and metabolic stress have been recognized by American Society for Clinical Investigation, American Association for the Advancement of Science, Association of American Physicians and American Society for Biochemistry and Molecular Biology.[8] In 2019, Schaffer was recruited to the Joslin Diabetes Center at Harvard Medical School [9][10]
Awards and honors
1993: Katz Basic Science Research Prize, American Heart Association[11]
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