Jerelle Joseph

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Jerelle A. Joseph is a computational chemist and academic from Dominica, who is also an advocate for representation and diversity in science. She is the founder of CariScholar, a network connecting students and academics from Caribbean countries.

Contents

Biography

Joseph grew up in the village of Vieille Case in Dominica. [1] Her mother was a nurse and her father worked a variety of jobs. [2] She graduated in 2012 with a BSc in Chemistry and mathematics from the University of the West Indies. This was followed by an MPhil in Chemistry at the same institution, graduating in 2014. She subsequently graduated with a DPhil in Chemistry from the University of Cambridge in 2018. [3] She subsequently continued her work at Cambridge in a post-doctoral role in the team of Rosana Collepardo-Guevara. [4] [1] In January 2023 she was appointed Assistant Professor of Chemical and Biological Engineering at Princeton University. [3] [5] [6] She works on the development of computational approaches to determine cellular organisation, in particular liquid–liquid phase separation. [7] [8]

Joseph is the founder of CariScholar, an organisation designed to connect students and academics from the Caribbean for mentoring. [1] [9] [10] Mentors include pscyhopharmocologist Kito Barrow, [11] physician Mondel George, [12] engineer Asher Williams, [13] machine learning scientist Randall Martyr, amongst others. [14]

Awards

Publications

Related Research Articles

<span class="mw-page-title-main">Bose–Einstein condensate</span> State of matter

In condensed matter physics, a Bose–Einstein condensate (BEC) is a state of matter that is typically formed when a gas of bosons at very low densities is cooled to temperatures very close to absolute zero. Under such conditions, a large fraction of bosons occupy the lowest quantum state, at which microscopic quantum mechanical phenomena, particularly wavefunction interference, become apparent macroscopically.

<span class="mw-page-title-main">Colloid</span> Mixture of an insoluble substance microscopically dispersed throughout another substance

A colloid is a mixture in which one substance consisting of microscopically dispersed insoluble particles is suspended throughout another substance. Some definitions specify that the particles must be dispersed in a liquid, while others extend the definition to include substances like aerosols and gels. The term colloidal suspension refers unambiguously to the overall mixture. A colloid has a dispersed phase and a continuous phase. The dispersed phase particles have a diameter of approximately 1 nanometre to 1 micrometre.

<span class="mw-page-title-main">Gallium</span> Chemical element, symbol Ga and atomic number 31

Gallium is a chemical element; it has symbol Ga and atomic number 31. Discovered by the French chemist Paul-Émile Lecoq de Boisbaudran in 1875, gallium is in group 13 of the periodic table and is similar to the other metals of the group.

<span class="mw-page-title-main">Kalinago</span> Group of people who live in Venezuela and the Lesser Antilles

The Kalinago, formerly known as Island Caribs or simply Caribs, are an indigenous people of the Lesser Antilles in the Caribbean. They may have been related to the Mainland Caribs (Kalina) of South America, but they spoke an unrelated language known as Island Carib. They also spoke a pidgin language associated with the Mainland Caribs.

<span class="mw-page-title-main">Carl Wieman</span> Nobel prize winning US physicist

Carl Edwin Wieman is an American physicist and educationist at Stanford University, and currently the A.D White Professor at Large at Cornell University. In 1995, while at the University of Colorado Boulder, he and Eric Allin Cornell produced the first true Bose–Einstein condensate (BEC) and, in 2001, they and Wolfgang Ketterle were awarded the Nobel Prize in Physics. Wieman currently holds a joint appointment as Professor of Physics and Professor in the Stanford Graduate School of Education, as well as the DRC Professor in the Stanford University School of Engineering. In 2020, Wieman was awarded the Yidan Prize in Education Research for "his contribution in developing new techniques and tools in STEM education." citation.

Digicel is a Jamaican-based Caribbean mobile phone network and home entertainment provider operating in 25 markets worldwide.

<span class="mw-page-title-main">Ionic liquid</span> Salt in the liquid state

An ionic liquid (IL) is a salt in the liquid state at ambient conditions. In some contexts, the term has been restricted to salts whose melting point is below a specific temperature, such as 100 °C (212 °F). While ordinary liquids such as water and gasoline are predominantly made of electrically neutral molecules, ionic liquids are largely made of ions. These substances are variously called liquid electrolytes, ionic melts, ionic fluids, fused salts, liquid salts, or ionic glasses.

<span class="mw-page-title-main">Cold trap</span> Device that condenses specific vapors and gases

In vacuum applications, a cold trap is a device that condenses all vapors except the permanent gases into a liquid or solid. The most common objective is to prevent vapors being evacuated from an experiment from entering a vacuum pump where they would condense and contaminate it. Particularly large cold traps are necessary when removing large amounts of liquid as in freeze drying.

Cadence-lypso is a fusion of cadence rampa from Haiti and calypso from Trinidad and Tobago that has also spread to other English speaking countries of the Caribbean. Originated in the 1970s by the Dominican band Exile One, it spread and became popular in the dance clubs around the Creole world and Africa as well as the French Antilles.

Cryochemistry is the study of chemical interactions at temperatures below −150 °C. It is derived from the Greek word cryos, meaning 'cold'. It overlaps with many other sciences, including chemistry, cryobiology, condensed matter physics, and even astrochemistry.

<span class="mw-page-title-main">2005 Dominican general election</span>

General elections were held in Dominica on 5 May 2005. The result was a victory for the ruling Dominica Labour Party, which won 12 of the 21 seats in the House of Assembly. The opposition United Workers' Party unsuccessfully made legal challenges to several of the constituency results.

<span class="mw-page-title-main">Dominica</span> Island country in the Caribbean

Dominica officially the Commonwealth of Dominica, is an island country in the Caribbean. The capital, Roseau, is located on the western side of the island. It is geographically situated as part of the Windward Islands chain in the Lesser Antilles archipelago in the Caribbean Sea. Dominica's closest neighbours are two constituent territories of the European Union, the overseas departments of France, Guadeloupe to the northwest and Martinique to the south-southeast. Dominica comprises a land area of 750 km2 (290 sq mi), and the highest point is Morne Diablotins, at 1,447 m (4,747 ft) in elevation. Its population was 71,293 at the 2011 census.

<span class="mw-page-title-main">Caribbean</span> Region to the east of Central America

The Caribbean is a subregion of the Americas that includes the Caribbean Sea and its islands, some of which are surrounded by the Caribbean Sea and some of which border both the Caribbean Sea and the North Atlantic Ocean; the nearby coastal areas on the mainland are often also included in the region. The region is southeast of the Gulf of Mexico and the North American mainland, east of Central America, and north of South America.

The glass–liquid transition, or glass transition, is the gradual and reversible transition in amorphous materials from a hard and relatively brittle "glassy" state into a viscous or rubbery state as the temperature is increased. An amorphous solid that exhibits a glass transition is called a glass. The reverse transition, achieved by supercooling a viscous liquid into the glass state, is called vitrification.

<span class="mw-page-title-main">Anthony A. Hyman</span> British biologist

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<span class="mw-page-title-main">Visa policy of Dominica</span> Policy on permits required to enter Dominica

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<span class="mw-page-title-main">Biomolecular condensate</span> Class of membrane-less organelles within biological cells

In biochemistry, biomolecular condensates are a class of membrane-less organelles and organelle subdomains, which carry out specialized functions within the cell. Unlike many organelles, biomolecular condensate composition is not controlled by a bounding membrane. Instead, condensates can form and maintain organization through a range of different processes, the most well-known of which is phase separation of proteins, RNA and other biopolymers into either colloidal emulsions, gels, liquid crystals, solid crystals or aggregates within cells.

<span class="mw-page-title-main">Dishevelled binding antagonist of beta catenin 1</span> Developmental protein

Dishevelled binding antagonist of beta catenin 1 is a protein that in humans is encoded by the DACT1 gene. Dact1 was originally described in 2002 as a negative regulator of Wnt signaling by binding and destabilizing Dishevelled. More recent investigation into the molecular function of Dact1 has identified its principle role in the cell as a scaffold to generate membrane-less biomolecular condensates through liquid-liquid phase separation. Mutations in the phase-separating regions of Dact1 lead to Townes-Brock Syndrome 2 while its overexpression is associated with bone metastasis.

LLPS often involves sequence regions that have unique functional characteristics, as well as the presence of prion-like and RNA-binding domains. Nowadays there are just a few methods to predict the propensity of a protein to drive LLPS. The range of biological mechanisms involved in LLPS, the limited knowledge about these mechanisms and the important context-dependent component of LLPS make this problem challenging. In the last years, despite the advances in this field, just few predictors, specific for LLPS, have been developed, trying to understand the relationship between protein sequence properties and the capability to drive LLPS. Here we will revise the state-of-the-art LLPS sequence-based predictors, briefly introducing them and explaining which are the individual protein characteristics that they identify in the context of LLPS.

References

  1. 1 2 3 "Dr Jerelle Joseph – Networks of evidence and expertise for public policy". www.csap.cam.ac.uk. Retrieved 2022-10-02.
  2. ↑ "Jerelle Joseph". The Biophysical Society. Retrieved 2023-06-03.
  3. 1 2 3 4 5 "Jerelle A. Joseph". Chemical and Biological Engineering. Retrieved 2022-10-02.
  4. 1 2 "Jerelle Joseph". Africans in STEM. Retrieved 2022-10-02.
  5. ↑ "Board approves 15 faculty appointments". Princeton University. Retrieved 2022-10-02.
  6. ↑ "New Duties for a Trio of Black Scholars". The Journal of Blacks in Higher Education. 2022-06-17. Retrieved 2023-06-03.
  7. ↑ "Biography | Gates Cambridge". Gates Cambridge. 2020-06-25. Retrieved 2022-10-02.
  8. ↑ "Dr Joseph". www.tcm.phy.cam.ac.uk. Retrieved 2022-10-02.
  9. ↑ "Jerelle A Joseph". Cavendish Inspiring. Retrieved 2023-06-03.
  10. ↑ "Caribbean Women in STEM". YourCommonwealth. Retrieved 2023-06-03.
  11. ↑ "Faculty Finder – The Chicago School". The Chicago School of Professional Psychology. Retrieved 2023-06-03.
  12. ↑ "Dr. Mondel George – Private Physician, Entrepreneur, Lifetime Learner". GrenSTEAM. 2021-02-16. Retrieved 2023-06-03.
  13. ↑ "Teaching | Asher Williams, Ph.D." Asher Williams. Retrieved 2023-06-03.
  14. ↑ "About me". rmartyr.gitlab.io. Retrieved 2023-06-03.
  15. ↑ Admin (2022-09-22). "The NYCD unveils 2022 national youth nominees". Dominica News Online. Retrieved 2022-10-02.
  16. ↑ "Jerelle A. Joseph | Chicago Materials Research Center | The University of Chicago". mrsec.uchicago.edu. Retrieved 2022-10-02.
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