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John James Rickard Macleod, was a Scottish biochemist and physiologist. He devoted his career to diverse topics in physiology and biochemistry, but was chiefly interested in carbohydrate metabolism. He is noted for his role in the discovery and isolation of insulin during his tenure as a lecturer at the University of Toronto, for which he and Frederick Banting received the 1923 Nobel prize in Physiology or Medicine. Awarding the prize to Macleod was controversial at the time, because according to Banting's version of events, Macleod's role in the discovery was negligible. It was not until decades after the events that an independent review acknowledged a far greater role than was attributed to him at first.
Sir Frederick Grant Banting was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential.
Charles Herbert Best was an American-Canadian medical scientist and one of the co-discoverers of insulin.
James Bertram Collip, was a Canadian biochemist who was part of the Toronto group which isolated insulin. He served as the Chair of the Department of Biochemistry at McGill University from 1928–1941 and Dean of Medicine at the University of Western Ontario from 1947–1961, where he was a charter member of The Kappa Alpha Society.
Albany Medical College (AMC) is a private medical school in Albany, New York, United States. It was founded in 1839 by Alden March and James H. Armsby and is one of the oldest medical schools in the nation. The college is part of the Albany Medical Center, which includes the Albany Medical Center Hospital. Along with Albany College of Pharmacy, Albany Law School, the Dudley Observatory, the Graduate College of Union University, and Union College, it is one of the constituent entities of Union University.
Charles H. Hollenberg, was a Canadian physician, educator and researcher.
Oliver Smithies was a British-American geneticist and physical biochemist. He is known for introducing starch as a medium for gel electrophoresis in 1955, and for the discovery, simultaneously with Mario Capecchi and Martin Evans, of the technique of homologous recombination of transgenic DNA with genomic DNA, a much more reliable method of altering animal genomes than previously used, and the technique behind gene targeting and knockout mice. He received the Nobel Prize in Physiology or Medicine in 2007 for his genetics work.
Barry Innis Posner, is a Canadian physician, research scientist and Professor in the Departments of Medicine and Anatomy & Cell Biology at McGill University, where he also manages the Polypeptide and Protein Hormone Laboratory.
Jeffrey M. Friedman is a molecular geneticist at New York City's Rockefeller University and an Investigator of the Howard Hughes Medical Institute. His discovery of the hormone leptin and its role in regulating body weight has had a major role in the area of human obesity. Friedman is a physician scientist studying the genetic mechanisms that regulate body weight. His research on various aspects of obesity received national attention in late 1994, when it was announced that he and his colleagues had isolated the mouse ob gene and its human homologue. They subsequently found that injections of the encoded protein, leptin, decreases body weight of mice by reducing food intake and increasing energy expenditure. Current research is aimed at understanding the genetic basis of obesity in human and the mechanisms by which leptin transmits its weight-reducing signal.
Robert Joseph Lefkowitz is an American physician and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University.
Robert Alan Good was an American physician who performed the first successful human bone marrow transplant between persons who were not identical twins. He is regarded as a founder of modern immunology.
Geoffrey Sharman Dawes, CBE, FRS, FRCOG, FRCP, FACOG(Hon), FAAP(Hon) was an English physiologist and was considered to be the foremost international authority on fetal and neonatal physiology.
Alvan R. Feinstein was a clinician, a researcher and an epidemiologist who made significant impact on clinical investigation, especially on the field of clinical epidemiology that he helped define. He is regarded as one of the fathers of modern clinical epidemiology. He died at the age of 75 in Toronto on 25 October 2001 and is survived by his wife and two children.
Dr. John Gerald "Gerry" FitzGerald was a Canadian physician and public health specialist who was instrumental in the control of diphtheria, first by producing and freely distributing antitoxin, and then in 1924 by using mass production to enable widespread use of the vaccine devised by Gaston Ramon.
Jeffrey Scott Flier is an American physician, endocrinologist, researcher, and the 21st Dean of the Faculty of Medicine at Harvard University.
Carl Ronald Kahn is an American physician and scientist, best known for his work with insulin receptors and insulin resistance in diabetes and obesity. He is the Chief Academic Officer at Joslin Diabetes Center, the Mary K. Iacocca Professor of Medicine at Harvard Medical School and a member of the National Academy of Sciences since 1999.
Doctor John Herbert Dirks is a Canadian physician.
Calvin Ralph Stiller, OC, OOnt, MD, FRCP(C), FCAHS, DSc(hon), LLD(hon),, is a highly esteemed Canadian physician, scientist, and entrepreneur. Although retired from a long and distinguished career as a member of the Schulich School of Medicine & Dentistry at Western University in London, Ontario, Stiller's impact on the Canadian health care system remains profound. His work in the area of organ transplantation and immunology, especially, was path-breaking in Canada and elsewhere, as was his creation of and support for various streams of top-level medical research, innovation, investment, and market application.
Daniel Joshua Drucker is a Canadian endocrinologist. A Fellow of the Royal Society, he is a professor of medicine at the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto. He is known for his research into intestinal hormones and their use in the treatment of diabetes and other metabolic diseases.
William G. Kaelin Jr. is an American Nobel Laureate physician-scientist. He is a professor of medicine at Harvard University and the Dana-Farber Cancer Institute. His laboratory studies tumor suppressor proteins. In 2016, Kaelin received the Albert Lasker Award for Basic Medical Research and the AACR Princess Takamatsu Award. He also won the Nobel Prize in Physiology or Medicine in 2019 along with Peter J. Ratcliffe and Gregg L. Semenza.
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