John Cumbers | |
---|---|
Born | 1979 (age 44–45) |
Alma mater | Brown University, University of Edinburgh, University of Hull |
Known for | synthetic biology, investing, biostrategy, space settlement |
Awards | National Academies Keck Futures Initiative in 2010 |
Scientific career | |
Fields | Molecular Biology, Cell Biology, Biochemistry, Synthetic Biology |
Institutions | SynBioBeta, NASA |
John Robert Cumbers (born 1979) is a British molecular biologist living in the San Francisco Bay Area. He is founder and chief executive officer of SynBioBeta which promotes synthetic biology to build a more sustainable universe. [1] He founded BetaSpace, a space settlement innovation network aimed at sustaining human life on and off our planet and is an operating partner at DCVC, a firm in Silicon Valley focused on investments in biotechnology. [2]
John Cumbers was born on October 5, 1979, in Watford, Hertfordshire, Eastern England, 15 miles north-west of London. Since childhood, he showed a keen interest in biology and information technology. Cumbers attended Queens' School in Bushey, Hertfordshire for high school. In 2004, he obtained his BSc in Computer Science with Information Engineering at the University of Hull, a public research university in Kingston upon Hull, Yorkshire. For his master's in science and bioinformatics, he studied at the University of Edinburgh in Scotland. He obtained his PhD in molecular biology, Cell Biology and Biochemistry at Brown University, under the supervision of Lynn J. Rothschild at NASA Ames Research Center where they initiated a program in space synthetic biology for NASA. [3]
After obtaining his doctorate, Cumbers served as lead for the Planetary Sustainability Initiative of the National Aeronautics and Space Administration (NASA), [4] the US federal agency responsible for aerospace research, aeronautics and the civilian space program. Between 2008 and 2015, Cumbers worked at the NASA Ames Research Center as a student and then contractor bioengineer and co-organized the first workshop on the applications of synthetic biology for space exploration. [5] He spent seven years in NASA's synthetic biology program, engineering organisms to provide food, fuel, medicine and other support materials for space missions [6] as well as mission design for space resource utilization, terraforming asteroids and life support.
In 2012, Cumbers founded SynBioBeta, a network for biological engineers, innovators and entrepreneurs who use biology to build a better and more sustainable universe. [7] [8] SynBioBeta hosts the Global Synthetic Biology Summit in San Francisco, California, every October. The Summit showcases the developments in synthetic biology that are transforming how people fuel, heal and feed the world. [9] [10] In addition to the Summit, SynBioBeta hosts a podcast and weekly digest.
In 2018, Cumbers founded BetaSpace, an innovation ecosystem investigating an off-Earth planet future. BetaSpace is focused on the broad areas of food and agriculture; water and waste; energy; and habitat and materials. [11] [12]
In 2017, Cumbers joined the Silicon Valley investment firm Data Collective (DCVC), a venture capital fund that backs entrepreneurs applying deep tech to transform giant industries. [13]
Cumbers is the author, with Karl Schmieder, of What’s Your Bio-Strategy? How to Prepare Your Business for Synthetic Biology [14] [15]
Cumbers has written on aging and insulin signalling, [16] the characterization of biological parts, [17] resource utilization on space missions, [18] synthetic biology in space, [19] [20] extremophiles (cyanobacteria and tardigrades) [21] and the impact of space resources on financial markets. [22] He is a regular contributor to Forbes.com, [23] writing on the impact of synthetic biology on manufacturing industries [24]
In 2010, Cumbers received the National Academies Keck Futures Initiative Award for his work in using synthetic biology in NASA's missions. [25]
Astrobiology, is a scientific field within the life and environmental sciences that studies the origins, early evolution, distribution, and future of life in the universe by investigating its deterministic conditions and contingent events. As a discipline, astrobiology is founded on the premise that life may exist beyond Earth.
Terraforming or terraformation ("Earth-shaping") is the hypothetical process of deliberately modifying the atmosphere, temperature, surface topography or ecology of a planet, moon, or other body to be similar to the environment of Earth to make it habitable for humans to live on.
Biomimetics or biomimicry is the emulation of the models, systems, and elements of nature for the purpose of solving complex human problems. The terms "biomimetics" and "biomimicry" are derived from Ancient Greek: βίος (bios), life, and μίμησις (mīmēsis), imitation, from μιμεῖσθαι (mīmeisthai), to imitate, from μῖμος (mimos), actor. A closely related field is bionics.
Synthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms, and it applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature.
George McDonald Church is an American geneticist, molecular engineer, chemist, serial entrepreneur, and pioneer in personal genomics and synthetic biology. He is the Robert Winthrop Professor of Genetics at Harvard Medical School, Professor of Health Sciences and Technology at Harvard University and Massachusetts Institute of Technology, and a founding member of the Wyss Institute for Biologically Inspired Engineering at Harvard University.
Biobased economy, bioeconomy or biotechonomy is economic activity involving the use of biotechnology and biomass in the production of goods, services, or energy. The terms are widely used by regional development agencies, national and international organizations, and biotechnology companies. They are closely linked to the evolution of the biotechnology industry and the capacity to study, understand, and manipulate genetic material that has been possible due to scientific research and technological development. This includes the application of scientific and technological developments to agriculture, health, chemical, and energy industries.
Christopher Voigt is an American synthetic biologist, molecular biophysicist, and engineer.
BMC Systems Biology was an open access peer-reviewed scientific journal that covered research in systems biology. Filling a gap in what was a new research field, the journal was established in 2007 and is published by BioMed Central. Part of the BMC Series of journals, it had a broad scope covering the engineering of biological systems, network modelling, quantitative analyses, integration of different levels of information and synthetic biology.
Tardigrades, known colloquially as water bears or moss piglets, are a phylum of eight-legged segmented micro-animals. They were first described by the German zoologist Johann August Ephraim Goeze in 1773, who called them Kleiner Wasserbär. In 1777, the Italian biologist Lazzaro Spallanzani named them Tardigrada, which means "slow steppers".
Lynn Justine Rothschild is an evolutionary biologist, astrobiologist and synthetic biologist at NASA's Ames Research Center, and is an adjunct professor at Brown University. She was a consulting Professor at Stanford University, where she taught Astrobiology and Space Exploration. At Ames, her research has focused on how life, particularly microbes, has evolved in the context of the physical environment, both on Earth and potentially beyond our planet's boundaries. Her research also explores the use of synthetic biology as an enabling tool for space travel. Since 2007, she has studied the effect of UV radiation on DNA synthesis, carbon metabolism and mutation/DNA repair in the Rift Valley of Kenya and the Bolivian Andes, and also in high altitude experiments atop Mount Everest, in balloon payloads with BioLaunch. She was the principal investigator of the first free-flyer synthetic biology payload which flew on the DLR EuCROPIS mission. In 2024, she received a Phase III NIAC grant to explore the use of fungi for constructing habitats on the Moon or Mars.
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Karmella Ann Haynes is a biomedical engineer and associate professor at the Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University. She researches how chromatin is used to control cell development in biological tissue.
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A living medicine is a type of biologic that consists of a living organism that is used to treat a disease. This usually takes the form of a cell or a virus that has been genetically engineered to possess therapeutic properties that is injected into a patient. Perhaps the oldest use of a living medicine is the use of leeches for bloodletting, though living medicines have advanced tremendously since that time.
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