Josef Coresh | |
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Academic background | |
Education | BS, Mathematics, Princeton University MHS, PhD, 1992, Johns Hopkins Bloomberg School of Public Health MD, 1992, Johns Hopkins University |
Thesis | Genetic epidemiology of Apolipoprotein B (1992img) |
Academic work | |
Institutions | NYU Langone Health |
Josef Coresh is an American epidemiologist. He is the Terry and Mel Karmazin Professor of Population Health,a Professor in the Department of Medicine,and the Founding Director of the Optimal Aging Institute at NYU Langone Health. He was previously the inaugural George W. Comstock Professor in the Department of Epidemiology at Johns Hopkins University,and the director of both the Cardiovascular Epidemiology Training Program and the George W. Comstock Center for Public Health Research and Prevention at Johns Hopkins School of Medicine.
Coresh attended Princeton University for his bachelor's degree in mathematics before enrolling at Johns Hopkins University for his medical degree,master's degree,and PhD. [1]
During his over 30-year tenure at Johns Hopkins,Dr. Coresh studied risk factors for vascular disease across different organs including the heart,kidney and brain with the goal of improving health and research. He developed a population-based longitudinal proteomic study of health in the ARIC (Atherosclerosis Risk in Communities) Study population. He used data of nearly 5000 proteins over three decades to gain insights into novel risk factors and pathways for dementia,heart disease,cancer and aging. [2] [3] Coresh also led the Cardiovascular Epidemiology Training Program at the Bloomberg School since 1997. [4] In this role,he was recognized with the AHA Lifestyle Council Mentorship Award as "a person who has provided exceptional individual and institutional mentoring and advocacy for cardiovascular epidemiology researchers." [5] His mentees included Elizabeth Selvin [6] and Morgan Grams. [7]
In 2007,his paper "Prevalence of chronic kidney disease in the United States" was ranked by Essential Science Indicators as one of the 20 most-cited "Hot Papers" over all fields and a "Highly Cited Paper in Clinical Medicine." [8] The following year,he was appointed both the Cardiovascular Epidemiology Training Program and the George W. Comstock Center for Public Health Research and Prevention at the Johns Hopkins School of Medicine. [9] Later,Coresh was appointed vice-chair of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative workgroup (for the Clinical Practice Guideline "Chronic Kidney Disease:Evaluation,Classification and Stratification") which has also led to his increased involvement in the international effort to address the public health burden of chronic kidney disease. [8] In 2009,Coresh was the co-author of "Identification of a urate transporter,ABCG2,with a common functional polymorphism causing gout" which received the PNAS paper Cozzarelli Prize for outstanding scientific excellence and originality. [10] The following year,the National Kidney Foundation gave Coresh the Garabed Eknoyan Award for his contributions to the field. He was also the recipient of the American Heart Association's Epidemiology and Prevention Mentoring Award. [8]
As the leader of the Chronic Kidney Disease Prognosis Consortium,Coresh analyzed data from 1.7 million participants recruited into 35 cohorts in dozens of countries from 1975 to 2011 and followed for an average of 5 years. He used this data to suggest that new therapies for kidney disease by revising the definition of kidney disease progression used during clinical trials. [11] Due to his overall research,Coresh was the recipient of the 2015 National Kidney Foundation's David Hume Award,their highest honor given to individuals "who exemplifies the high ideals of scholarship and humanism in an outstanding manner." [12]
In fall 2020,Dr. Coresh co-authored a kidney study using international data from over nine million individuals "to develop and validate a risk-scoring calculation that adds blood and urine measures of kidney disease to the current standard method in the United States for assessing cardiovascular disease risk." [13] In October 2020,he was the recipient of the Belding H. Scribner Lifetime Achievement Award from the American Society of Nephrology for his career-long contributions to the practice of nephrology. [14]
In 2023,Dr. Coresh joined NYU Grossman School of Medicine,a part of NYU Langone Health.
Chronic kidney disease (CKD) is a type of long-term kidney disease,in which either there is a gradual loss of kidney function occurs over a period of months to years,or abnormal kidney structure. Initially generally no symptoms are seen,but later symptoms may include leg swelling,feeling tired,vomiting,loss of appetite,and confusion. Complications can relate to hormonal dysfunction of the kidneys and include high blood pressure,bone disease,and anemia. Additionally CKD patients have markedly increased cardiovascular complications with increased risks of death and hospitalization.
JoAnn Elisabeth Manson is an American physician and professor known for her pioneering research,public leadership,and advocacy in the fields of epidemiology and women's health.
George Wills Comstock was a public health physician,epidemiologist,and educator. He was known for significant contributions to public health,specifically in the fields of micronutrient deficiencies,tuberculosis,and cardiovascular disease. He served as the editor-in-chief for the American Journal of Epidemiology.
Kamyar Kalantar-Zadeh is a US American physician doing research in nephrology,kidney dialysis,nutrition,and epidemiology. He is best known as a specialist in kidney disease nutrition and chronic kidney disease and for his hypothesis about the longevity of individuals with chronic disease states,also known as reverse epidemiology including obesity paradox. According to this hypothesis,obesity or hypercholesterolemia may counterintuitively be protective and associated with greater survival in certain groups of people,such as elderly individuals,dialysis patients,or those with chronic disease states and wasting syndrome (cachexia),whereas normal to low body mass index or normal values of serum cholesterol may be detrimental and associated with worse mortality. Kalantar-Zadeh is also known for his expertise in kidney dialysis therapy,including incremental dialysis,as well as renal nutrition. He is the brother of Kourosh Kalantar-zadeh,who is an Australian scientist involved in research in the fields of materials sciences,nanotechnology,and transducers.
The Atherosclerosis Risk in Communities (ARIC) Study is a multi-site,prospective,biracial cohort study funded by the National Heart,Lung,and Blood Institute of the National Institutes of Health. The ARIC Study was designed to investigate the etiology and clinical outcomes of atherosclerosis. A total of 15,792 middle-aged men and women were enrolled from four U.S. communities:
Lawrence J. Appel is the C. David Molina Professor of Medicine and Director of the Welch Center for Prevention,Epidemiology and Clinical Research at Johns Hopkins University,a joint program of the Johns Hopkins University School of Medicine and the Bloomberg School of Public Health. Dr. Appel is a primary care internist who holds a primary appointment in the Department of Medicine with joint appointments in the Department of Epidemiology,International Health,and Nursing. In addition,he directs the ProHealth Clinical Research Unit. The focus of his career is the conduct of clinical,epidemiologic,and translational research pertaining to the prevention and control of high blood pressure,cardiovascular-kidney diseases,and other chronic conditions,primarily through nutrition-based interventions.
Neil R. Powe is an American professor of medicine at the University of California,San Francisco and the chief of medicine at the Zuckerberg San Francisco General Hospital and Trauma Center. Previously he was professor of medicine at the Johns Hopkins University School of Medicine. His research has mainly related to kidney disease,cardiovascular disease and health disparities.
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Andrew S. Levey is an American nephrologist who transformed chronic kidney disease (CKD) clinical practice,research,and public health by developing equations to estimate glomerular filtration rate (GFR),and leading the global standardization of CKD definition and staging.
Colin Baigent is a British academic physician and cardiovascular epidemiologist. He is a professor of epidemiology,Director of the Medical Research Council Population Health Research Unit at the University of Oxford,and deputy director of the Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU),part of Oxford Population Health. His work is focused in the design and coordination of large-scale randomised trials and the use of meta-analysis to assess the efficacy and safety of drugs for the prevention of cardiovascular disease (CVD) or premature death.
Erin Kathleen Donnelly Michos is an American cardiologist. She is an associate professor of Medicine and Director of Women's Cardiovascular Health at Johns Hopkins School of Medicine. Michos is also an Associate Faculty of the Welch Center for Prevention,Epidemiology and Clinical Research at Johns Hopkins,and has a joint faculty appointment in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health.
David Wesley Dowdy is an American infectious disease epidemiologist. He is the B. Frank and Kathleen Polk Professor at Johns Hopkins Bloomberg School of Public Health.
Wendy Susan Post is an American cardiologist. She is the Director of Cardiovascular Research for the Division of Cardiology and Director of Research for the Hopkins Cardiovascular Fellowship Training Program.
Michael John Klag is an American internist and epidemiologist. For eight years,he was the Director of the Division of General Internal Medicine and was the first Vice Dean for Clinical Investigation at the Johns Hopkins School of Medicine.
Felicia Hill-Briggs was an American behavioral and social scientist.
Xiaobin Wang is an American molecular epidemiologist. She is the Zanvyl Krieger Professor in Children's Health at Children's Memorial Institute and director of the Center on the Early Life Origins of Disease at the Johns Hopkins Bloomberg School of Public Health.
Leigh Ebony Boulware is an American general internist,physician-scientist,and clinical epidemiologist. She is the Dean of Wake Forest School of Medicine and chief science officer and vice chief academic officer of Advocate Health. Boulware formerly served as the Nanaline Duke Distinguished Professor of Medicine and director of the Clinical and Translational Science Institute at the Duke University School of Medicine.
Rulan S. Parekh is an American-Canadian clinician-scientist and nephrologist. She is the vice president of research,education and innovation at Women's College Hospital and former senior scientist in Child Health Evaluative Sciences and Associate Chief of Clinical Research at SickKids.
Eliseo Guallar is an American epidemiologist. He is a professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health with a joint appointment at the Johns Hopkins University School of Medicine. His research focuses on cardiovascular diseases.
Morgan Erika Grams is an American nephrologist. She is the Co-Director of the Division of Precision Medicine,and the Susan and Morris Mark Professor in the Departments of Medicine and Population Health at NYU Langone Health.