Judith Potashkin

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Judith Potashkin
Alma materState University of New York at Buffalo
Scientific career
InstitutionsRosalind Franklin University of Medicine and Science
Thesis Isolation and characterization of residual nuclei from S̲a̲c̲c̲h̲a̲r̲o̲m̲y̲c̲e̲s̲ c̲e̲r̲e̲v̲i̲s̲i̲a̲e̲  (1985)

Judith Ann Potashkin is an American professor at Rosalind Franklin University of Medicine and Science. She is best known for her research on diseases such as Parkinson's and Alzheimer's. She is an elected fellow of the American Association for the Advancement of Science.

Contents

Education and career

Potashkin has an undergraduate degree from Lehigh University (1977), and an M.S. in from Pennsylvania State University where she worked on the connection between ribosomal RNA synthesis and viruses. [1] In 1985, Potashkin earned her Ph.D. from the State University of New York at Buffalo working on residual nuclei in yeast. [2] Following her Ph.D. she was a postdoctoral scientist at Cold Spring Harbor Laboratory. She moved to Chicago Medical School in 1990 where she is a tenured professor. [3]

Research

Potashkin is known for her research on the role of RNA in neurodegenerative diseases. Her early research examined residual nuclei in Saccharomyces cerevisiae . [4] She went on to examine the genes involved in RNA splicing [5] and identified defects in RNA processing. [6] Her research on Parkinson's disease includes defining biomarkers, [7] [8] [9] characterizing dysregulated pathways, [10] and assessing the role of nutrition. [11] Her research also extends into investigations of Alzheimer's disease. [12]

Selected publications

Awards and honors

Potashkin was elected a fellow of the American Association for the Advancement of Science in 2020. [13]

References

  1. Potashkin, Judith Ann (1979). An investigation of a possible mechanism of stimulation of ribosomal ribonucleic acid synthesis by simian virus 40 T-antigen (Thesis). OCLC   79946151.
  2. Potashkin, Judith Ann (1985). Isolation and characterization of residual nuclei from S̲a̲c̲c̲h̲a̲r̲o̲m̲y̲c̲e̲s̲ c̲e̲r̲e̲v̲i̲s̲i̲a̲e̲ (Thesis). OCLC   14878436.
  3. "Judith A. Potashkin, PhD". Rosalind Franklin University. Retrieved 2021-11-04.
  4. Potashkin, Judith A.; Huberman, Joel A. (1986-07-01). "Characterization of DNA sequences associated with residual nuclei of Saccharomyces cerevisiae" . Experimental Cell Research. 165 (1): 29–40. doi:10.1016/0014-4827(86)90530-6. ISSN   0014-4827. PMID   3519258.
  5. Potashkin, Judith; Naik, Karuna; Wentz-Hunter, Kelly (1993-10-22). "U2AF Homolog Required for Splicing in Vivo" . Science. 262 (5133): 573–575. Bibcode:1993Sci...262..573P. doi:10.1126/science.8211184. PMID   8211184.
  6. Potashkin, J.; Frendewey, D. (1990-02-01). "A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing". The EMBO Journal. 9 (2): 525–534. doi:10.1002/j.1460-2075.1990.tb08139.x. ISSN   0261-4189. PMC   551696 . PMID   2406130.
  7. Chen-Plotkin, Alice S.; Albin, Roger; Alcalay, Roy; Babcock, Debra; Bajaj, Vikram; Bowman, Dubois; Buko, Alex; Cedarbaum, Jesse; Chelsky, Daniel; Cookson, Mark R.; Dawson, Ted M. (2018-08-15). "Finding useful biomarkers for Parkinson's disease". Science Translational Medicine. 10 (454): eaam6003. doi:10.1126/scitranslmed.aam6003. PMC   6097233 . PMID   30111645.
  8. Santiago, Jose A.; Potashkin, Judith A. (2015-02-17). "Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson's disease". Proceedings of the National Academy of Sciences. 112 (7): 2257–2262. Bibcode:2015PNAS..112.2257S. doi: 10.1073/pnas.1423573112 . ISSN   0027-8424. PMC   4343174 . PMID   25646437.
  9. Potashkin, Judith A.; Santiago, Jose A.; Ravina, Bernard M.; Watts, Arthur; Leontovich, Alexey A. (2012-08-27). "Biosignatures for Parkinson's Disease and Atypical Parkinsonian Disorders Patients". PLOS ONE. 7 (8): e43595. Bibcode:2012PLoSO...743595P. doi: 10.1371/journal.pone.0043595 . ISSN   1932-6203. PMC   3428307 . PMID   22952715.
  10. Santiago, Jose A.; Potashkin, Judith A. (2013). "Shared dysregulated pathways lead to Parkinson's disease and diabetes" . Trends in Molecular Medicine. 19 (3): 176–186. doi:10.1016/j.molmed.2013.01.002. PMID   23375873.
  11. Seidl, Stacey; Santiago, Jose; Bilyk, Hope; Potashkin, Judith (2014). "The emerging role of nutrition in Parkinson's disease". Frontiers in Aging Neuroscience. 6: 36. doi: 10.3389/fnagi.2014.00036 . ISSN   1663-4365. PMC   3945400 . PMID   24639650.
  12. Santiago, Jose A.; Potashkin, Judith A. (2021-02-12). "The Impact of Disease Comorbidities in Alzheimer's Disease". Frontiers in Aging Neuroscience. 13: 631770. doi: 10.3389/fnagi.2021.631770 . ISSN   1663-4365. PMC   7906983 . PMID   33643025.
  13. "Judith Potashkin, PhD, Elected AAAS Fellow". Rosalind Franklin University. December 17, 2020. Retrieved 2021-11-04.