Kelly J. Henning

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Kelly J. Henning
NationalityAmerican

Kelly J. Henning is an epidemiologist and medical doctor currently leading the public health program of Bloomberg Philanthropies. She has led the program since it began in 2007. She was the first person to serve as director of epidemiology for the New York City Department of Health and Mental Hygiene. [1] [2] Henning said of working in public health "I have the opportunity to help improve the health and lives of millions of people. That's what really speaks to me." [3]

Contents

Career

Henning received her MD from Tufts University School of Medicine and completed internal medicine training at the University of Pennsylvania where she also served as an associate professor of infectious diseases and hospital epidemiology. [2] She completed her epidemiology training at the U.S. Center for Disease Control and Prevention Epidemic Intelligence Service in 1988. [4]

Henning served as the first director of the epidemiology division of New York City's Department of Health and Mental Hygiene from 2003 to 2006. [2] Since 2007, she has led the public health program of Bloomberg Philanthropies, the foundation established by former New York City Mayor Mike Bloomberg. Priorities for the program include devoting $1 billion to curbing tobacco use in poorer countries, reducing the number of preventable traffic injuries and deaths around the world, and helping countries to improve public health data collection with the goal of addressing public health problems." [5] [6] [7] [8]

Henning characterized the work on curbing tobacco use as focused on "demand reduction." She described this as "smoke-free public places, advertising bans, availability of cessation services, pack warnings, and other ways of educating the public, and perhaps most importantly raising taxes on tobacco because price is one of the key drivers to helping people quit and not start using tobacco." [9]

On the wider work with Bloomberg Philanthropies on noncommunicable diseases, Henning told NPR: "Cancer, heart attacks, stroke, chronic lung disease: this is a group of diseases that cause more than 40 million deaths a year." [10]

Henning has contributed to more than 30 peer-reviewed research publications and presented at more than 11 national scientific meetings. She has been invited to deliver more than 28 lectures or lead discussions on a range of topics including bioterrorism, pandemic flu and smallpox. [11] [12]

Selected publications

Related Research Articles

<span class="mw-page-title-main">Q fever</span> Coxiella burnetii infection

Q fever or query fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus, or semen of infected animals. Rarely, the disease is tick-borne. The incubation period can range from 9 to 40 days. Humans are vulnerable to Q fever, and infection can result from even a few organisms. The bacterium is an obligate intracellular pathogenic parasite.

<span class="mw-page-title-main">Tryptophan</span> Chemical compound

Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromatic beta carbon substituent. Tryptophan is also a precursor to the neurotransmitter serotonin, the hormone melatonin, and vitamin B3. It is encoded by the codon UGG.

Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. The risk of developing EMS increases with larger doses of tryptophan and increasing age. Some research suggests that certain genetic polymorphisms may be related to the development of EMS. The presence of eosinophilia is a core feature of EMS, along with unusually severe myalgia.

<span class="mw-page-title-main">Myalgia</span> Muscle pain

Myalgia is the medical term for muscle pain. Myalgia is a symptom of many diseases. The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, especially when there has been no trauma.

<span class="mw-page-title-main">Eosinophil</span> Variety of white blood cells

Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply.

<span class="mw-page-title-main">Eosinophilia</span> Blood condition

Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5×108/L (500/μL). Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 109/L (i.e. 1,500/μL). The hypereosinophilic syndrome is a sustained elevation in this count above 1.5 × 109/L (i.e. 1,500/μL) that is also associated with evidence of eosinophil-based tissue injury.

<span class="mw-page-title-main">5-Hydroxytryptophan</span> Chemical compound

5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.

<span class="mw-page-title-main">Hypereosinophilic syndrome</span> Unexplained chronic eosinophila

Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.

<span class="mw-page-title-main">Löffler's syndrome</span> Medical condition

Löffler's syndrome is a disease in which eosinophils accumulate in the lung in response to a parasitic infection. The parasite can be Ascaris, Strongyloides stercoralis, or Dirofilaria immitis which can enter the body through contact with the soil. The symptoms of Löffler's syndrome include those of a parasitic infection such as abdominal pain and cramping, skin rashes and fatigue. Löffler's syndrome itself will cause difficulty breathing, wheeze, coughing as well as a fever.

<span class="mw-page-title-main">Showa Denko</span> Japanese chemicals company

Showa Denko K. K., founded in 1939 by the merger of Nihon Electrical Industries and Showa Fertilizers, both established by a Japanese entrepreneur Nobuteru Mori, is a Japanese chemical company producing chemical products and industrial materials.

Eosinophilic fasciitis, also known as Shulman's syndrome, is an inflammatory disease that affects the fascia, other connective tissues, surrounding muscles, blood vessels and nerves. Unlike other forms of fasciitis, eosinophilic fasciitis is typically self-limited and confined to the arms and legs, although it can require treatment with corticosteroids, and some cases are associated with aplastic anemia.

<span class="mw-page-title-main">Toxic oil syndrome</span> Foodborne illness

Toxic oil syndrome (TOS) or simply toxic syndrome is a musculoskeletal disease. A 1981 outbreak in Spain which affected about 20,000 people, with over 300 dying within a few months and a few thousand remaining disabled, is thought to have been caused by contaminated colza (rapeseed) oil. It was unique because of its size, the novelty of the clinical condition, and the complexity of its aetiology. Its first appearance was as a lung disease, with unusual features, though the symptoms initially resembled a lung infection. The disease appeared to be restricted to certain geographical localities, and several members of a family could be affected, even while their neighbours had no symptoms. Following the acute phase, a range of other chronic symptoms was apparent.

Gleich's syndrome is a rare disease in which the body swells up episodically (angioedema), associated with raised antibodies of the IgM type and increased numbers of eosinophil granulocytes, a type of white blood cells, in the blood (eosinophilia). It was first described in 1984.

<span class="mw-page-title-main">Tom Frieden</span> American physician

Thomas R. Frieden is an American infectious disease and public health physician. He serves as president and CEO of Resolve to Save Lives, a $225 million, five-year initiative to prevent epidemics and cardiovascular disease.

<span class="mw-page-title-main">Kynurenine pathway</span> Metabolic pathway that produces the NAD coenzyme

The kynurenine pathway is a metabolic pathway leading to the production of nicotinamide adenine dinucleotide (NAD+). Metabolites involved in the kynurenine pathway include tryptophan, kynurenine, kynurenic acid, xanthurenic acid, quinolinic acid, and 3-hydroxykynurenine. The kynurenine pathway is responsible for total catabolization of tryptophan about 95%. Disruption in the pathway is associated with certain genetic and psychiatric disorders.

Tropical pulmonary eosinophilia, is characterized by cough, bronchospasm, wheezing, abdominal pain, and an enlarged spleen. Occurring most frequently in the Indian subcontinent and Southeast Asia, TPE is a clinical manifestation of lymphatic filariasis, a parasitic infection caused by filarial roundworms that inhabit the lymphatic vessels, lymph nodes, spleen, and bloodstream. Three species of filarial roundworms, all from the Onchocercidae family, cause human lymphatic filariasis: Wuchereria bancrofti, Brugia malayi, and Brugia timori.

David DuPuy Celentano is a noted epidemiologist and professor who has contributed significantly to the promotion of research on HIV/AIDS and other sexually transmitted infections (STIs). He is the Charles Armstrong chair of the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. He holds joint appointments with the school’s departments of Health Policy and Management, Health Behavior and Society, and International Health, and the Johns Hopkins University School of Medicine’s Division of Infectious Diseases.

Eosinophilic myocarditis is inflammation in the heart muscle that is caused by the infiltration and destructive activity of a type of white blood cell, the eosinophil. Typically, the disorder is associated with hypereosinophilia, i.e. an eosinophil blood cell count greater than 1,500 per microliter. It is distinguished from non-eosinophilic myocarditis, which is heart inflammation caused by other types of white blood cells, i.e. lymphocytes and monocytes, as well as the respective descendants of these cells, NK cells and macrophages. This distinction is important because the eosinophil-based disorder is due to a particular set of underlying diseases and its preferred treatments differ from those for non-eosinophilic myocarditis.

Professor Angela Webster is a clinical epidemiologist at the Sydney School of Public Health, University of Sydney, nephrologist and transplant physician at Westmead Hospital and director of Evidence Integration at the NHMRC Clinical Trials Centre, University of Sydney.

References

  1. "Kelly Henning". Health Affairs. doi:10.1377/hauthor20150928.576239 (inactive 31 January 2024). Retrieved 10 May 2018.{{cite journal}}: CS1 maint: DOI inactive as of January 2024 (link)
  2. 1 2 3 "Dr. Kelly Henning | Bloomberg Philanthropies". Bloomberg Philanthropies. Retrieved 2018-05-10.
  3. "Dr Kelly Henning, Bloomberg Philanthropies Public Health Lead talks tobacco control on the eve of WCTOH". 17th World Conference on Tobacco or Health. Retrieved 10 May 2018.
  4. "Epidemic Intelligence Service Officers by Class Year, 1951–2005". American Journal of Epidemiology. 174 (suppl 11): i–x. 2011-11-30. doi: 10.1093/aje/kwr449 . ISSN   0002-9262.
  5. "Billionaire Michael Bloomberg Wants to Make the World Quit Smoking". Fortune. Retrieved 2018-05-10.
  6. "The High Toll of Traffic Injuries: Unacceptable and Preventable". World Bank. Retrieved 2018-05-10.
  7. Guest, CIO Central. "Bloomberg's Data Initiative: Big Data For Social Good In 2018". Forbes. Retrieved 2018-05-10.
  8. "For better health, countries must understand death". Devex. 2016-08-23. Retrieved 2018-05-10.
  9. "STOP – Bloomberg's response to tobacco industry tactics". Devex. 2018-03-23. Retrieved 2018-05-14.
  10. "Michael Bloomberg Aim To Fight Noncommunicable Diseases Complicated By President's Pitch". NPR.org. Retrieved 2018-05-14.
  11. Henning, Kelly J.; Brennan, Patrick J.; Hoegg, Cindy; O'Rourke, Eileen (February 2004). "Health System Preparedness for Bioterrorism: Bringing the Tabletop to the Hospital". Infection Control and Hospital Epidemiology. 25 (2): 146–155. doi:10.1086/502366. ISSN   0899-823X. PMID   14994941. S2CID   35069977.
  12. Henning, Kelly J. (2004-09-24). "What is syndromic surveillance?". MMWR Supplements. 53: 5–11. ISSN   2380-8942. PMID   15714620.
  13. Henning, K J; Pollack, D M; Friedman, S M (June 1992). "A neonatal hepatitis B surveillance and vaccination program: New York City, 1987 to 1988". American Journal of Public Health. 82 (6): 885–888. doi:10.2105/ajph.82.6.885. ISSN   0090-0036. PMC   1694181 . PMID   1585970.
  14. Frieden, T. R.; Sowell, A. L.; Henning, K. J.; Huff, D. L.; Gunn, R. A. (February 1992). "Vitamin A levels and severity of measles. New York City". American Journal of Diseases of Children. 146 (2): 182–186. doi:10.1001/archpedi.1992.02160140048019. ISSN   0002-922X. PMID   1285727.
  15. Henning, KJ; Jean-Baptiste, E; Singh, T; Hill, RH; Friedman, SM (February 1993). "Eosinophilia-myalgia syndrome in patients ingesting a single source of L-tryptophan". The Journal of Rheumatology. 20 (2): 273–8. ISSN   0315-162X. PMID   8474064.
  16. Back, E. E.; Henning, K. J.; Kallenbach, L. R.; Brix, K. A.; Gunn, R. A.; Melius, J. M. (April 1993). "Risk factors for developing eosinophilia myalgia syndrome among L-tryptophan users in New York". The Journal of Rheumatology. 20 (4): 666–672. ISSN   0315-162X. PMID   8496862.
  17. Henning, Kelly J.; Bell, Eleanor; Braun, James; Barker, Nancy D. (August 1995). "A community-wide outbreak of hepatitis a: Risk factors for infection among homosexual and bisexual men". The American Journal of Medicine. 99 (2): 132–136. doi:10.1016/S0002-9343(99)80132-6. ISSN   0002-9343. PMID   7625417.
  18. Henning, Kelly J.; Delencastre, Herminia; Eagan, Janet; Boone, Natalie; Brown, Arthur; Chung, Marilyn; Wollner, Norma; Armstrong, Donald (October 1996). "Vancomycin-resistant Enterococcus faecium on a pediatric oncology ward: duration of stool shedding and incidence of clinical infection". The Pediatric Infectious Disease Journal. 15 (10): 848–54. doi:10.1097/00006454-199610000-00004. ISSN   0891-3668. PMID   8895914.
  19. Henning, Kelly J. (1997-04-09). "A National Survey of Immunization Practices Following Allogeneic Bone Marrow Transplantation". JAMA: The Journal of the American Medical Association. 277 (14): 1148–51. doi:10.1001/jama.1997.03540380062032. ISSN   0098-7484. PMID   9087470.
  20. Henning, Kelly J.; Hall, Elvira L.; Dwyer, Diane M.; Billmann, Lillian; Schuchat, Anne; Johnson, Judith A.; Harrison, Lee H. (April 2001). "Invasive Group B Streptococcal Disease in Maryland Nursing Home Residents". The Journal of Infectious Diseases. 183 (7): 1138–1142. doi: 10.1086/319278 . ISSN   0022-1899. PMID   11237844.
  21. Henning, Kelly J.; Brennan, Patrick J.; Hoegg, Cindy; O'Rourke, Eileen; Dyer, Bernard D.; Grace, Thomas L. (February 2004). "Health System Preparedness for Bioterrorism: Bringing the Tabletop to the Hospital". Infection Control & Hospital Epidemiology. 25 (2): 146–155. doi:10.1086/502366. ISSN   0899-823X. PMID   14994941. S2CID   35069977.
  22. Henning, Kelly J. (2004). "What is Syndromic Surveillance?". Morbidity and Mortality Weekly Report. 53: 7–11. JSTOR   23315680.
  23. Frieden, Thomas R.; Das-Douglas, Moupali; Kellerman, Scott E.; Henning, Kelly J. (December 2005). "Applying Public Health Principles to the HIV Epidemic". New England Journal of Medicine. 353 (22): 2397–2402. doi: 10.1056/nejmsb053133 . ISSN   0028-4793. PMID   16319391.
  24. Myers, Julie E.; Henning, Kelly J.; Frieden, Thomas R.; Larson, Kelly; Begier, Beth; Sepkowitz, Kent A. (2007). "Written Consent For Human Immunodeficiency Virus Testing". Public Health Reports. 122 (4): 433–434. ISSN   0033-3549. PMC   1888515 . PMID   17639644.
  25. Larson, Kelly; Henning, Kelly; Peden, Margie (12 March 2012). "The importance of data for global road safety". Traffic Injury Prevention. 13:sup1: 3–4. doi:10.1080/15389588.2012.671737. PMID   22414121. S2CID   37038339.
  26. Larson, Kelly; Henning, Kelly (December 2013). "Implementing proven road safety interventions saves lives". Injury. 44: S3. doi:10.1016/s0020-1383(13)70205-5. ISSN   0020-1383. PMID   24377775.