Kenneth D Harris

Last updated
Kenneth D Harris
Nationality British, American
AwardsWellcome Trust Senior Investigator 2011, European Research Council Advanced Investigator 2014, Royal Society Wolfson Research Merit Award, EPSRC Leadership Fellowship, Alfred P. Sloan Fellowship
Scientific career
Fields Neuroscience, Computational Neuroscience, Systems Neuroscience
Institutions University College London (professor)

Kenneth D. Harris is a neuroscientist at University College London. He is most known for his contributions to the understanding of the neural code used by vast populations of neurons. [1] [2] [3] [4] [5] Among his discoveries is the finding that populations in sensory areas of the brain also code for body movements. [6] Harris has contributed to the development of silicon probes [7] and most recently of Neuropixels probes. [8] With these probes, he and his team discovered that engagement in a task activates neurons throughout the brain. [9]

Harris obtained his PhD from UCL in the laboratory of Michael Recce, and did his postdoctoral studies at Rutgers University in the laboratory of Gyorgy Buzsaki. [10] He is a Professor of Quantitative Neuroscience [11] at the UCL Queen Square Institute of Neurology, where he co-directs the Cortical Processing Laboratory [12] with Matteo Carandini. Harris is a founding member of the International Brain Laboratory.

Related Research Articles

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Matteo Carandini is a neuroscientist who studies the visual system. He is currently a professor at University College London, where he co-directs the Cortical Processing Laboratory with Kenneth D Harris.

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Susan L. Ackerman is an American neuroscientist and geneticist. Her work has highlighted some of the genetic and biochemical factors that are involved in the development of the central nervous system and age-related neurodegeneration. Her research is aimed at helping scientists understand what causes several types of neurodegeneration in mammals. This research, and others' like it, may lead to cures for neurodegenerative diseases. Ackerman is a professor at University of California San Diego. She was formerly a professor at the Jackson Laboratory and the Sackler School of Graduate Biomedical Sciences at Tufts University. She also serves as an adjunct professor at the University of Maine, Orono. Ackerman was an associate geneticist at Massachusetts General Hospital in Boston, Massachusetts.

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<span class="mw-page-title-main">International Brain Laboratory</span>

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Dragana Rogulja is a Serbian neuroscientist and circadian biologist who is an assistant professor in Neurobiology within the Harvard Medical School Blavatnik Institute of Neurobiology. Rogulja explores the molecular mechanisms governing sleep in Drosophila as well as probing how circadian mechanisms integrate sensory information to drive behavior. Rogulja uses mating behavior in Drosophila to explore the neural circuits linking internal states to motivated behaviors.

Jessica Cardin is an American neuroscientist who is an associate professor of neuroscience at Yale University School of Medicine. Cardin's lab studies local circuits within the primary visual cortex to understand how cellular and synaptic interactions flexibly adapt to different behavioral states and contexts to give rise to visual perceptions and drive motivated behaviors. Cardin's lab applies their knowledge of adaptive cortical circuit regulation to probe how circuit dysfunction manifests in disease models.

<span class="mw-page-title-main">Carsen Stringer</span> American computational neuroscientist

Carsen Stringer is an American computational neuroscientist and Group Leader at the Howard Hughes Medical Institute Janelia Research Campus. Stringer uses machine learning and deep neural networks to visualize large scale neural recordings and then probe the neural computations that give rise to visual processing in mice. Stringer has also developed several novel software packages that enable cell segmentation and robust analyses of neural recordings and mouse behavior.

Neuropixels probes are electrodes developed in 2017 to record the activity of hundreds of neurons in the brain. The probes are based on CMOS technology and have 1,000 recording sites arranged in two rows on a thin, 1-cm long shank.

References

  1. ↑ Harris, Kenneth D.; Csicsvari, Jozsef; Hirase, Hajime; Dragoi, George; Buzsáki, György (2003-07-31). "Organization of cell assemblies in the hippocampus". Nature. 424 (6948): 552–556. Bibcode:2003Natur.424..552H. doi:10.1038/nature01834. ISSN   1476-4687. PMID   12891358. S2CID   4420968.
  2. ↑ Luczak, Artur; Barthó, Peter; Marguet, Stephan L.; Buzsáki, György; Harris, Kenneth D. (2007-01-02). "Sequential structure of neocortical spontaneous activity in vivo". Proceedings of the National Academy of Sciences of the United States of America. 104 (1): 347–352. Bibcode:2007PNAS..104..347L. doi: 10.1073/pnas.0605643104 . ISSN   0027-8424. PMC   1765463 . PMID   17185420.
  3. ↑ Renart, Alfonso; de la Rocha, Jaime; Bartho, Peter; Hollender, Liad; Parga, Néstor; Reyes, Alex; Harris, Kenneth D. (2010-01-29). "The asynchronous state in cortical circuits". Science. 327 (5965): 587–590. Bibcode:2010Sci...327..587R. doi:10.1126/science.1179850. ISSN   1095-9203. PMC   2861483 . PMID   20110507.
  4. ↑ Stringer, Carsen; Pachitariu, Marius; Steinmetz, Nicholas; Carandini, Matteo; Harris, Kenneth D. (2019). "High-dimensional geometry of population responses in visual cortex". Nature. 571 (7765): 361–365. doi:10.1038/s41586-019-1346-5. ISSN   1476-4687. PMC   6642054 . PMID   31243367. Q72587818
  5. ↑ Stringer, Carsen; Pachitariu, Marius; Steinmetz, Nicholas; Reddy, Charu Bai; Carandini, Matteo; Harris, Kenneth D. (2019). "Spontaneous behaviors drive multidimensional, brainwide activity". Science. 364 (6437): 255. Bibcode:2019Sci...364..255S. doi:10.1126/science.aav7893. ISSN   1095-9203. PMC   6525101 . PMID   31000656.
  6. ↑ Cepelewicz, Jordana. "'Noise' in the Brain Encodes Surprisingly Important Signals". Quanta Magazine. Retrieved 2019-11-11.
  7. ↑ "$5M for international neuroscience 'dream team'". University of Michigan News. 2015-11-03. Retrieved 2019-09-23.
  8. ↑ HHMI. "New Silicon Probes Record Activity of Hundreds of Neurons Simultaneously". HHMI.org. Retrieved 2019-09-23.
  9. ↑ Abbott, Alison (2020-08-11). "Inside the mind of an animal". Nature. 584 (7820): 182–185. Bibcode:2020Natur.584..182A. doi: 10.1038/d41586-020-02337-x . PMID   32782378.
  10. ↑ "Neurotree - Kenneth D. Harris Family Tree". neurotree.org. Retrieved 2019-09-23.
  11. ↑ UCL (2019-02-08). "harris-kenneth". UCL Division of Biosciences. Retrieved 2019-09-23.
  12. ↑ UCL. "UCL - London's Global University". Cortexlab. Retrieved 2019-09-23.


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