Kerstin Lindblad-Toh

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Kerstin Lindblad-Toh
Kerstin Lindblad-Toh, Goran Gustafsson prize laureates 2013 a.jpg
Lindblad-Toh in 2013
Born(1970-06-13)June 13, 1970 (age 52)
CitizenshipSwedish and American
Known forThe 200 Mammals Project, Mammalian Genomes, Dog Disease Genetics
Scientific career
FieldsComparative Genomics, Human Genetics, Immunology, Cancer
InstitutionsBroad Institute and Uppsala University
Thesis  (1998)

Kerstin Lindblad-Toh is a scientist in comparative genomics, specializing in mammalian genetics. She is the Scientific Director of vertebrate genomics at the Broad Institute [1] and a professor in comparative genomics at Uppsala University. [2] In 2010 she co-founded Science for Life Laboratory (SciLifeLab) together with Mathias Uhlén and acted as Co-Director until 2015. As the leader of the Broad Institute's Mammalian Genome Initiative she has led the effort to sequence and analyze the genomes of various mammals, including mouse, dog, chimpanzee, horse, rabbit and opossum. [3] She has researched extensively on the genetics of dogs, identifying genes and genetic variants important in disease susceptibility, morphology and behavior. [1]

Contents

Lindblad-Toh is elected to the National Academy of Sciences of the United States and the Royal Swedish Academy of Sciences. [4]

Education and early career

Lindblad-Toh was born 1970 in Stockholm, Sweden. She studied molecular biology as an undergraduate at Karolinska Institute. [5] In 1988, she received her Ph.D. from the Department of Molecular Medicine at Karolinska Institute. She worked on several projects as a postdoctoral fellow at the Whitehead Institute/MIT Center for Genome Research together with Eric Lander, including mouse SNP discovery, the development of genotyping technologies and association studies in human disease. [6] In 2002, she co-authored the paper describing the initial genome sequence of the mouse, [7] and in 2005 she published the first genome sequence of the domestic dog. [8]

Awards and honors

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References

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  3. "29 Mammals Project". Broad Institute. 2008-04-30. Retrieved 2020-07-12.
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  5. Hulth, Annica. "Kerstin Lindblad-Toh - Uppsala University, Sweden". www.uppsalauniversitet.se. Archived from the original on 2020-07-13. Retrieved 2020-07-13.
  6. Broad Institute: Kerstin Lindblad-Toh Archived 2011-07-16 at the Wayback Machine , accessed on December 19, 2009
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  8. Lindblad-Toh, Kerstin; Wade, Claire M.; Mikkelsen, Tarjei S.; Karlsson, Elinor K.; Jaffe, David B.; Kamal, Michael; Clamp, Michele; Chang, Jean L.; Kulbokas, Edward J.; Zody, Michael C.; Mauceli, Evan (2005-12-08). "Genome sequence, comparative analysis and haplotype structure of the domestic dog". Nature. 438 (7069): 803–819. doi: 10.1038/nature04338 . ISSN   1476-4687. PMID   16341006.
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