Ladeana Hillier

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Ladeana Hillier is a biomedical engineer and computational biologist from the University of Washington. [1] [2] She was one of the earliest scientists involved in the Human Genome Project [3] and is noted for her work in various branches of DNA sequencing, [4] [5] [6] [7] [8] as well as for having co-developed Phred, [9] a widely used DNA trace analyzer. [10] [11] Her multidisciplinary approach integrates Computational biology and Gene in her work, where she created a software to speed up sequencing. [12] LaDeana W. Hillier performs integrative study on Gene expression and Regulation of gene expression. [13] She also worked with the Children's Hospital Oakland Research Institute & Wellcome Trust Sanger Institute. [14]

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References

  1. Wenz, C (2005) Author Profile: Ladeana Hillier. Nurture 1, pp. 2.
  2. "LaDeana W. Hillier | University of Washington | 142 Publications | 6056 Citations | Related Authors". SciSpace - Author. Retrieved 2025-03-17.
  3. Sulston, J and Ferry, G (2002) The Common Thread: A Story of Science, Politics, Ethics, and the Human Genome, Joseph Henry Press.
  4. Hillier, LW et al. (2003) The DNA sequence of human chromosome 7. Nature 424(6945), 157–164.
  5. Hillier, LW et al. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature 434(7034), 724–731.
  6. Hillier, LW et al. (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432(7018), 695–716.
  7. Hillier, LW et al. (2008) Whole-genome sequencing and variant discovery in C-elegans. Nature Methods 5(2), 183–188.
  8. Hillier, LW et al. (1996) Generation and analysis of 280,000 human expressed sequence tags. Genome Research 6(9), 807–828.
  9. Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Research 8(3), 175–185. PMID   9521921 full article
  10. Koboldt, D. C. and Miller, R. D. (2011) Identification of Polymorphic Markers for Genetic Mapping, chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.
  11. Highsmith, W. E. (2006) Electrophoretic Methods for Mutation Detection and DNA Sequencing, chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press
  12. Carlson, Klerla (1999). "Outlook - Washington School of Medicine" (PDF).
  13. "LaDeana W. Hillier: Genetics H-index & Awards - Academic Profile". Research.com. Retrieved 2025-03-17.
  14. . 2011-10-01. doi:10.35802/098051 https://doi.org/10.35802/098051 .{{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)