Latarcin

Last updated
Latarcin
Identifiers
SymbolLatarcin
Pfam PF10279
InterPro IPR018802
OPM superfamily 259
OPM protein 2pco
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

Latarcins are short antimicrobial peptides from the venom of the spider Lachesana tarabaevi . [1] Latarcins adopt an amphipathic alpha-helical structure in the plasma membrane. Possible pharmacological applications for latarcins include antimicrobial and anticancer treatments. [2]

References

  1. ↑ Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV (July 2006). "Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity". J. Biol. Chem. 281 (30): 20983–92. Bibcode:2006JBiCh.28120983K. doi: 10.1074/jbc.M602168200 . PMID   16735513.
  2. ↑ Dubovskii, P.V.; Vassilevski, A.A.; Kozlov, S.A.; Feofanov, A.V.; Grishin, E.V.; Efremov, R.G. (2015). "Latarcins: versatile spider venom peptides". Cellular and Molecular Life Sciences. 72 (23): 4501–4522. doi:10.1007/s00018-015-2016-x. PMC   11113828 . PMID   26286896. S2CID   14177431.
This article incorporates text from the public domain Pfam and InterPro: IPR018802
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