Late congenital syphilitic oculopathy

Late congenital syphilitic oculopathy
Specialty	Ophthalmology

Late congenital syphilitic oculopathy is a disease of the eye, a manifestation of late congenital syphilis. ^[1]

Signs and symptoms

It can appear as:

• Interstitial keratitis ^[1] – this commonly appears between ages 6 and 12. Symptoms include lacrimation and photophobia. Pathological vascularization of the cornea cause it to turn pink or salmon colored. 90% of cases affect both eyes.
• Episcleritis or scleritis ^[1] – nodules appear in or overlying the sclera (white of eye)
• Iritis or iris papules ^[1] – vascular infiltration of the iris causes rosy color change and yellow/red nodules.
• Chorioretinitis, papillitis, retinal vasculitis ^[1] – retinal changes can resemble retinitis pigmentosa.
• Exudative retinal detachment

Congenital syphilis is categorized by the age of the child. Early congenital syphilis occurs in children under 2 years old, and late congenital syphilis in children at or greater than 2 years old. Manifestations of late congenital syphilis are similar to those of secondary syphilis and tertiary syphilis in adults.

References

1. Koundanya, Vikram V.; Tripathy, Koushik (2025). "Syphilis Ocular Manifestations". StatPearls. StatPearls Publishing.

External links

• eMedicine: Ocular Manifestations of Syphilis