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A motor neuron is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. There are two types of motor neuron – upper motor neurons and lower motor neurons. Axons from upper motor neurons synapse onto interneurons in the spinal cord and occasionally directly onto lower motor neurons. The axons from the lower motor neurons are efferent nerve fibers that carry signals from the spinal cord to the effectors. Types of lower motor neurons are alpha motor neurons, beta motor neurons, and gamma motor neurons.
The motor system is the set of central and peripheral structures in the nervous system that support motor functions, i.e. movement. Peripheral structures may include skeletal muscles and neural connections with muscle tissues. Central structures include cerebral cortex, brainstem, spinal cord, pyramidal system including the upper motor neurons, extrapyramidal system, cerebellum, and the lower motor neurons in the brainstem and the spinal cord.
The brainstem is the posterior part of the brain, continuous with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem.
The grey column refers to a somewhat ridge-shaped mass of grey matter in the spinal cord. This presents as three columns: the anterior grey column, the posterior grey column, and the lateral grey column, all of which are visible in cross-section of the spinal cord.
The spinothalamic tract is a sensory pathway to the thalamus. From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.
The dorsal column–medial lemniscus pathway (DCML) is a sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (position) from the skin and joints. It transmits information from the body to the primary somatosensory cortex in the postcentral gyrus of the parietal lobe of the brain. The pathway receives information from sensory receptors throughout the body, and carries this in nerve tracts in the white matter of the dorsal columns of the spinal cord to the medulla, where it is continued in the medial lemniscus, on to the thalamus and relayed from there through the internal capsule and transmitted to the somatosensory cortex. The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem.
The precentral gyrus is a prominent gyrus on the surface of the posterior frontal lobe of the brain. It is the site of the primary motor cortex that in humans is cytoarchitecturally defined as Brodmann area 4.
The spinocerebellar tract is a nerve tract originating in the spinal cord and terminating in the same side (ipsilateral) of the cerebellum.
The sympathetic ganglia, or autonomic ganglia, are the ganglia of the sympathetic nervous system. Ganglia are 20,000 to 30,000 afferent and efferent nerve cell bodies that run along on either side of the spinal cord. Afferent nerve cell bodies bring information from the body to the brain and spinal cord, while efferent nerve cell bodies bring information from the brain and spinal cord to the rest of the body. The cell bodies create long sympathetic chains that are on either side of the spinal cord. They also form para- or pre-vertebral gangalia of gross anatomy.
The lateral grey column is one of the three grey columns of the spinal cord ; the others being the anterior and posterior grey columns. The lateral grey column is primarily involved with activity in the sympathetic division of the autonomic motor system. It projects to the side as a triangular field in the thoracic and upper lumbar regions of the postero-lateral part of the anterior grey column.
The anterior corticospinal tract is a small bundle of descending fibers that connect the cerebral cortex to the spinal cord. Descending tracts are pathways by which motor signals are sent from upper motor neurons in the brain to lower motor neurons which then directly innervate muscle to produce movement. The anterior corticospinal tract is usually small, varying inversely in size with the lateral corticospinal tract, which is the main part of the corticospinal tract.
The posterolateral tract is a small strand situated in relation to the tip of the posterior column close to the entrance of the posterior nerve roots. It is present throughout the spinal cord, and is most developed in the upper cervical regions.
Alpha (α) motor neurons (also called alpha motoneurons), are large, multipolar lower motor neurons of the brainstem and spinal cord. They innervate extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. Alpha motor neurons are distinct from gamma motor neurons, which innervate intrafusal muscle fibers of muscle spindles.
The medullary pyramids are paired white matter structures of the brainstem's medulla oblongata that contain motor fibers of the corticospinal and corticobulbar tracts – known together as the pyramidal tracts. The lower limit of the pyramids is marked when the fibers cross (decussate).
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column. It encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and entering the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around 45 cm (18 in) in men and around 43 cm (17 in) long in women. The diameter of the spinal cord ranges from 13 mm in the cervical and lumbar regions to 6.4 mm in the thoracic area.
Anterolateral corticospinal tract is a subdivision of the corticospinal tract in the spinal cord. It is formed by approximately 2% of the corticospinal fibers that do not cross to the opposite side of the brainstem in the pyramidal decussation. This tract descends in the lateral white column anterior to the lateral corticospinal tract.
Ventral propriospinal tract is a collection of nerve fibers, ascending, descending, crossed and uncrossed, that interconnect various levels of the spinal cord. It is a component of the white anterior columns. The fibers are largely myelinated and run close to the spinal central gray for the length of the cord. Shorter fibers are closer to, longer fibers further from the gray. Other prominent components of the anterior columns are the medial longitudinal fasciculus of the spinal cord, the anterior spinothalamic tract of the spinal cord and the lateral vestibulospinal tract of the spinal cord. The ventral propriospinal tract is one of three propriospinal tracts in which most pathways intrinsic to the spinal cord are located. The others are the dorsal propriospinal tract and the lateral propriospinal tract.,
The dorsal propriospinal tract is a collection of nerve fibers, ascending, descending, crossed and uncrossed, that interconnect various levels of the spinal cord. It is a component of the white posterior column. Myelinated fibers are located adjacent to the spinal central gray. Shorter fibers are closer to, longer fibers further from the gray. Some fibers are unmyelinated and scattered through the posterior column. The tract is one of three propriospinal tracts in which most pathways intrinsic to the spinal cord are located. The others are the ventral propriospinal tract and the lateral propriospinal tract.
Propriospinal tracts are collections of nerve fibers ascending, descending, crossed and uncrossed, that interconnect various levels of the spinal cord. They are located in the white columns of the spinal cord where the columns meet the spinal central gray. Shorter fibers are located closer and longer fibers farther from the gray. The tracts include the ventral propriospinal tract, the lateral propriospinal tract and the dorsal propriospinal tract. Some authors include the semilunar tract in this category. A few other fibers intrinsic to the cord run in the dorsolateral fasciculus of the spinal cord and the septomarginal tract.
The proper fasciculi, or spinospinal fasciculi, or propriospinal tracts, are groups of short fibres, ascending and descending, and crossed and uncrossed, within the spinal cord. These fibres are grouped into anterior, posterior, and lateral regions and make up a spinal pathway. Descending dorsal root collaterals are often included in the pathway.