Laura Rosella

Last updated
Laura C. A. Rosella
Alma mater University of Toronto
Scientific career
InstitutionsUniversity of Toronto
Thesis A population based approach to diabetes mellitus risk prediction : methodological advances and practical applications.  (2009)

Laura C. A. Rosella is a Canadian epidemiologist who is an Associate Professor at the Dalla Lana School of Public Health in the University of Toronto. She studies public health and the social determinants of health. Rosella holds a Canada Research Chair in Population Health Analytics.

Contents

Early life and education

Rosella was an undergraduate student at the University of Toronto, where she majored in health science and epidemiology. [1] She remained at the University for her graduate studies, where she evaluated public health risk in people with diabetes mellitus. [2]

Research and career

Rosella is a professor at the Dalla Lana School of Public Health at the University of Toronto. [3] Rosella is the Scientific Director of the Population Health Analytics Laboratory. [4] She has looked to prevent diabetes, through regular screenings and partnerships with provincial health ministries. [1] She developed DPoRT, a Diabetes Population Risk Tool which identifies the optimum cut offs for health screenings to prevent adverse medical outcomes. [5] At the same time, Rosella investigates how people living with diabetes accumulate chronic conditions. She combines her understanding of social and behavioural risk factor data with an understanding of healthcare utilisation to eliminate persistent health inequalities. [1]

In November 2020, Rosella joined the Institute for Better Health as the Stephen Family Research Chair in Community Health. [6] In this capacity she looks to improve public health decision making and promote the equitable distribution of healthcare. [6] Rosella has evaluated the use of machine learning in predicting population health. She found that the majority of machine learning applications only made use of traditional data sources, and rarely used big data. [7]

Rosella served as a member of the Ontario COVID-19 Science Advisory Table as a part of the group's Modelling Consensus Table. [8]

Awards and honours

Selected publications

Related Research Articles

<span class="mw-page-title-main">Type 2 diabetes</span> Type of diabetes mellitus with high blood sugar and insulin resistance

Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Symptoms may also include increased hunger, feeling tired, and sores (wounds) that do not heal. Often symptoms come on slowly. Long-term complications from high blood sugar include heart disease, strokes, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to amputations. The sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon.

<span class="mw-page-title-main">Gestational diabetes</span> Medical condition

Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. Gestational diabetes generally results in few symptoms; however, it increases the risk of pre-eclampsia, depression, and of needing a Caesarean section. Babies born to mothers with poorly treated gestational diabetes are at increased risk of macrosomia, of having hypoglycemia after birth, and of jaundice. If untreated, diabetes can also result in stillbirth. Long term, children are at higher risk of being overweight and of developing type 2 diabetes.

<span class="mw-page-title-main">Impaired fasting glucose</span> Medical condition

Impaired fasting glucose is a type of prediabetes, in which a person's blood sugar levels during fasting are consistently above the normal range, but below the diagnostic cut-off for a formal diagnosis of diabetes mellitus. Together with impaired glucose tolerance, it is a sign of insulin resistance. In this manner, it is also one of the conditions associated with metabolic syndrome.

<span class="mw-page-title-main">Prediabetes</span> Predisease state of hyperglycemia with high risk for diabetes

Prediabetes is a component of the metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus. It usually does not cause symptoms but people with prediabetes often have obesity, dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension. It is also associated with increased risk for cardiovascular disease (CVD). Prediabetes is more accurately considered an early stage of diabetes as health complications associated with type 2 diabetes often occur before the diagnosis of diabetes.

There are high rates of diabetes in First Nation people compared to the general Canadian population. Statistics from 2011 showed that 17.2% of First Nations people living on reserves had type 2 diabetes.

<span class="mw-page-title-main">Epidemiology of diabetes</span>

Globally, an estimated 537 million adults are living with diabetes, according to 2019 data from the International Diabetes Federation. Diabetes was the 9th-leading cause of mortality globally in 2020, attributing to over 2 million deaths annually due to diabetes directly, and to kidney disease due to diabetes. The primary causes of type 2 diabetes is diet and physical activity, which can contribute to increased BMI, poor nutrition, hypertension, alcohol use and smoking, while genetics is also a factor. Diabetes prevalence is increasing rapidly; previous 2019 estimates put the number at 463 million people living with diabetes, with the distributions being equal between both sexes icidence peaking around age 55 years old. The number is projected to 643 million by 2030, or 7079 individuals per 100,000, with all regions around the world continue to rise. Type 2 diabetes makes up about 85-90% of all cases. Increases in the overall diabetes prevalence rates largely reflect an increase in risk factors for type 2, notably greater longevity and being overweight or obese. The prevalence of African Americans with diabetes is estimated to triple by 2050, while the prevalence of whites is estimated to double. The overall prevalence increases with age, with the largest increase in people over 65 years of age. The prevalence of diabetes in America is estimated to increase to 48.3 million by 2050.

<span class="mw-page-title-main">Diabetes</span> Group of endocrine diseases characterized by high blood sugar levels

Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. Classic symptoms include thirst, polyuria, weight loss, and blurred vision. If left untreated, the disease can lead to various health complications, including disorders of the cardiovascular system, eye, kidney, and nerves. Untreated or poorly treated diabetes accounts for approximately 1.5 million deaths every year.

Prabhat Jha is an Indian-Canadian epidemiologist currently working in the field of global health.

<span class="mw-page-title-main">Elizabeth Barrett-Connor</span>

Elizabeth Louise Barrett-Connor was Chief of the Division of Epidemiology and Distinguished Professor at the University of California, San Diego. She investigated the role of hormones in pathogenesis of cardiovascular disease, diabetes and osteoporosis.

Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System, and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute, and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic, McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.

Nishi Chaturvedi is a Professor of Clinical Epidemiology at University College London. Her research considers how ethnicity and lifestyle impact people's risk factors for disease. During the COVID-19 pandemic, Chaturvedi explained that the increased mortality rate for people from black and minority ethnic backgrounds was due to societal inequality and how this intersects with healthcare.

<span class="mw-page-title-main">Cuilin Zhang</span> Chinese epidemiologist and physician-scientist

Cuilin Zhang is a Chinese-American epidemiologist and physician-scientist researching the roles of genetic and environmental factors in the pathogenesis of gestational diabetes, type 2 diabetes, and obesity and health consequences of these complications. Zhang is a senior investigator and acting chief of the epidemiology branch at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Dr. Shelley Deeks, MD, MHSc, FRCPC, FFAFPM, is a Canadian public health expert who is the chair of the National Advisory Committee on Immunization. Her advertised "specialities include communicable disease control, outbreak investigations, vaccine safety, epidemiology and program evaluation." She is a fellow of the Royal College of Physicians of Canada and the Australian Faculty of Public Health Medicine. Deeks was the executive lead in Ontario's COVID-19 pandemic response in 2020 in her role at Public Health Ontario.

<span class="mw-page-title-main">David Fisman</span> Canadian epidemiologist

David N. Fisman is a University of Toronto professor in the area of epidemiology at the Dalla Lana School of Public Health. He also works as an infectious disease specialist and consultant at the University Health Network.

Scarlett Bellamy is an American public health researcher who is a Professor of the Department of Epidemiology and Biostatistics at Drexel University. At Drexel she is Associate Dean of Diversity, Inclusion and Faculty Development.

Lynda D. Lisabeth is an American epidemiologist who is Professor and Senior Associate Dean for Faculty Affairs in the School of Public Health at the University of Michigan. Her research considers the epidemiology of stroke in the United States, and she has worked with the National Institute of Neurological Disorders and Stroke on the advancement of stroke research.

<span class="mw-page-title-main">Sherita Hill Golden</span> American physician

Sherita Hill Golden is an American physician who is the Hugh P. McCormick Family Professor of Endocrinology and Metabolism at Johns Hopkins University. She also serves as vice president and chief diversity officer. Her research considers biological and systems influences on diabetes and its outcomes. She was elected Fellow of National Academy of Medicine in 2021.

Biological inequity, also known as biological inequality, refers to “systematic, unfair, and avoidable stress-related biological differences which increase risk of disease, observed between social groups of a population”. The term developed by Centric Lab aims to unify societal factors with the biological underpinnings of health inequities – the unfair and avoidable differences in health status and risks between social groups of a population - such that these inequalities can be investigated in a holistic manner.

Lorna E. Thorpe is an American epidemiologist who is a professor and Director of the Division of Epidemiology at NYU Langone Health. She serves as Vice Chair of Strategy and Planning in the Department of Population Health and on the Board of the American College of Epidemiology.

Prof David Guwatudde is a Ugandan academic and researcher. He is currently a professor of Epidemiology and Biostatistics in the Department of Epidemiology and Biostatistics at the School of Public Health, Makerere University College of Health Sciences.

References

  1. 1 2 3 "BBDC Member Profile". Banting & Best Diabetes Centre. 2019-01-07. Retrieved 2021-05-30.
  2. ↑ Rosella, Laura C. A (2011). A population based approach to diabetes mellitus risk prediction: methodological advances and practical applications (Thesis). Ottawa: Library and Archives Canada = Bibliothèque et Archives Canada. OCLC   785764075.
  3. ↑ "Rosella, Laura C." Dalla Lana School of Public Health. Retrieved 2021-05-30.
  4. ↑ "Our Team". Population Health Analytics Laboratory | Toronto, ON. Retrieved 2021-05-30.
  5. ↑ Rosella, Laura C.; Manuel, Douglas G.; Burchill, Charles; Stukel, Thérèse A.; PHIAT-DM team (July 2011). "A population-based risk algorithm for the development of diabetes: development and validation of the Diabetes Population Risk Tool (DPoRT)". Journal of Epidemiology and Community Health. 65 (7): 613–620. doi:10.1136/jech.2009.102244. ISSN   1470-2738. PMC   3112365 . PMID   20515896.
  6. 1 2 "IBH Welcomes New Research Chairs". Institute for Better Health. Retrieved 2021-05-30.
  7. ↑ Morgenstern, Jason Denzil; Buajitti, Emmalin; O'Neill, Meghan; Piggott, Thomas; Goel, Vivek; Fridman, Daniel; Kornas, Kathy; Rosella, Laura C. (2020-10-27). "Predicting population health with machine learning: a scoping review". BMJ Open. 10 (10): e037860. doi:10.1136/bmjopen-2020-037860. ISSN   2044-6055. PMC   7592293 . PMID   33109649.
  8. ↑ "Our Partners". Ontario COVID-19 Science Advisory Table . Archived from the original on 2022-09-02. Retrieved 2022-09-02.
  9. ↑ "PHO Scientist Wins Award from Canadian Society for Epidemiology and Biostatistics". Public Health Ontario. Archived from the original on 2021-06-02. Retrieved 2021-05-30.
  10. ↑ "Past Award Winners – Early Career – Society for Epidemiologic Research" . Retrieved 2021-05-30.
  11. ↑ "Laura Rosella named a recipient of Canada's Top 40 Under 40". Dalla Lana School of Public Health. 2018-06-27. Retrieved 2021-05-30.
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