Lindsay Cahill

Last updated
Lindsay Cahill
Born
Barrie, Ontario, Canada
Alma mater McMaster University
AwardsBanting Research Foundation Discovery Award
Scientific career
Institutions Memorial University of Newfoundland
McMaster University
Warwick University
Hospital for Sick Children
Thesis Solid-state NMR Studies of Lithium Ion Dynamics in Cathode Materials for Lithium Ion Batteries  (2008)
Doctoral advisor Gillian Goward

Lindsay Cahill is a Canadian chemist who uses Magnetic Resonance Imaging (MRI ) to study metabolic abnormalities in pregnancy. [1] She has published more than 70 articles on her research related to nuclear magnetic resonance in studying electrochemical materials and for imaging animal fetuses and placenta. [2] She has published widely-used protocols for the imaging of mouse brains. [3]

Contents

Education and early career

Cahill completed her B.Sc. and Ph.D. in chemistry at McMaster University. In her Ph.D., she used solid-state NMR to study lithium-ion batteries. [4] She employed 6Li and 7Li solid-state NMR to study the dynamics of the transport of lithium ions through materials. [5]

After completing her PhD, she held a postdoctoral fellowship in the Department of Physics at Warwick University under the supervision of Mark Smith (physicist). In 2009, she moved to the Mouse Imaging Center at the Hospital for Sick Children. [6] One of her contributions at the Mouse Imaging Center was the identification of a mouse model for autoimmune encephalomyelitis that may serve as a better model for multiple sclerosis in humans than previous models. [7] Prior to her scientific career, she was a captain in the Barrie Safety Patrol.

Independent career

.Cahill was appointed as an Assistant Professor in the Department of Chemistry at the Memorial University of Newfoundland in January 2020. [8] She received the Discovery Award from the Banting Research Foundation and a Discovery Grant from the Natural Sciences and Engineering Research Council of Canada. [9] [10] In 2022, Cahill was the project leader for a grant from the Canadian Foundation for Innovation to establish the Micro-Ultrasound Lab at Memorial University. [11] She was also named one of the 2022 Future Leaders in Canadian Brain Research Program by the Brain Canada foundation. [12]

Awards

Related Research Articles

<span class="mw-page-title-main">John Macleod (physiologist)</span> Scottish Nobel laureate

John James Rickard Macleod,, was a Scottish biochemist and physiologist. He devoted his career to diverse topics in physiology and biochemistry, but was chiefly interested in carbohydrate metabolism. He is noted for his role in the discovery and isolation of insulin during his tenure as a lecturer at the University of Toronto, for which he and Frederick Banting received the 1923 Nobel prize in Physiology or Medicine.

<span class="mw-page-title-main">Lithium</span> Chemical element with atomic number 3 (Li)

Lithium is a chemical element; it has symbol Li and atomic number 3. It is a soft, silvery-white alkali metal. Under standard conditions, it is the least dense metal and the least dense solid element. Like all alkali metals, lithium is highly reactive and flammable, and must be stored in vacuum, inert atmosphere, or inert liquid such as purified kerosene or mineral oil. It exhibits a metallic luster. It corrodes quickly in air to a dull silvery gray, then black tarnish. It does not occur freely in nature, but occurs mainly as pegmatitic minerals, which were once the main source of lithium. Due to its solubility as an ion, it is present in ocean water and is commonly obtained from brines. Lithium metal is isolated electrolytically from a mixture of lithium chloride and potassium chloride.

<span class="mw-page-title-main">Frederick Banting</span> Canadian medical scientist and doctor

Sir Frederick Grant Banting was a Canadian pharmacologist, orthopedist, and field surgeon. For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physiology or Medicine with John Macleod.

<span class="mw-page-title-main">Lithium hydroxide</span> Chemical compound

Lithium hydroxide is an inorganic compound with the formula LiOH. It can exist as anhydrous or hydrated, and both forms are white hygroscopic solids. They are soluble in water and slightly soluble in ethanol. Both are available commercially. While classified as a strong base, lithium hydroxide is the weakest known alkali metal hydroxide.

<span class="mw-page-title-main">Natural Sciences and Engineering Research Council</span> Agency of the Government of Canada

The Natural Sciences and Engineering Research Council of Canada is the major federal agency responsible for funding natural sciences and engineering research in Canada. NSERC directly funds university professors and students as well as Canadian companies to perform research and training. With funding from the Government of Canada, NSERC supports the research of over 41,000 students, trainees and professors at universities and colleges in Canada with an annual budget of CA$1.1 billion in 2015. Its current director is Alejandro Adem.

<span class="mw-page-title-main">TRIUMF</span> Particle physics laboratory in Canada

TRIUMF is Canada's national particle accelerator centre. It is considered Canada's premier physics laboratory, and consistently regarded as one of the world's leading subatomic physics research centres. Owned and operated by a consortium of universities, it is on the south campus of one of its founding members, the University of British Columbia in Vancouver, British Columbia, Canada. It houses the world's largest normal conducting cyclotron, a source of 520 MeV protons, which was named an IEEE Milestone in 2010. Its accelerator-focused activities involve particle physics, nuclear physics, nuclear medicine, materials science, and detector and accelerator development.

<span class="mw-page-title-main">John B. Goodenough</span> American materials scientist (1922–2023)

John Bannister Goodenough was an American materials scientist, a solid-state physicist, and a Nobel laureate in chemistry. From 1986 he was a professor of Materials Science, Electrical Engineering and Mechanical Engineering, at the University of Texas at Austin. He is credited with identifying the Goodenough–Kanamori rules of the sign of the magnetic superexchange in materials, with developing materials for computer random-access memory and with inventing cathode materials for lithium-ion batteries.

Naturally occurring lithium (3Li) is composed of two stable isotopes, lithium-6 (6Li) and lithium-7 (7Li), with the latter being far more abundant on Earth. Both of the natural isotopes have an unexpectedly low nuclear binding energy per nucleon when compared with the adjacent lighter and heavier elements, helium and beryllium. The longest-lived radioisotope of lithium is 8Li, which has a half-life of just 838.7(3) milliseconds. 9Li has a half-life of 178.2(4) ms, and 11Li has a half-life of 8.75(6) ms. All of the remaining isotopes of lithium have half-lives that are shorter than 10 nanoseconds. The shortest-lived known isotope of lithium is 4Li, which decays by proton emission with a half-life of about 91(9) yoctoseconds, although the half-life of 3Li is yet to be determined, and is likely to be much shorter, like 2He which undergoes proton emission within 10−9 s.

Jens Frahm is a German biophysicist and physicochemist. He is Research Group Leader of the Biomedical NMR group at the Max Planck Institute (MPI) for Multidisciplinary Sciences in Göttingen, Germany.

<span class="mw-page-title-main">Inositol-phosphate phosphatase</span> Class of enzymes

The enzyme Inositol phosphate-phosphatase is of the phosphodiesterase family of enzymes. It is involved in the phosphophatidylinositol signaling pathway, which affects a wide array of cell functions, including but not limited to, cell growth, apoptosis, secretion, and information processing. Inhibition of inositol monophosphatase may be key in the action of lithium in treating bipolar disorder, specifically manic depression.

<span class="mw-page-title-main">David MacLennan</span>

David Herman MacLennan was a Canadian biochemist and geneticist known for his basic work on proteins that regulate calcium flux through the sarcoplasmic reticulum (SR), thereby regulating muscle contraction and relaxation, and for his discoveries in the field of muscle diseases caused by genetic defects in calcium regulatory proteins.

<span class="mw-page-title-main">Rachid Yazami</span> Moroccan scientist

Rachid Yazami is a Moroccan scientist, engineer, and inventor. He is best known for his critical role in the development of the graphite anode for lithium-ion batteries and his research on fluoride ion batteries.

In chemistry, ion transport number, also called the transference number, is the fraction of the total electric current carried in an electrolyte by a given ionic species i:

<span class="mw-page-title-main">Akira Yoshino</span> Japanese chemist (born 1948)

Akira Yoshino is a Japanese chemist. He is a fellow of Asahi Kasei Corporation and a professor at Meijo University in Nagoya. He created the first safe, production-viable lithium-ion battery, which became used widely in cellular phones and notebook computers. Yoshino was awarded the Nobel Prize in Chemistry in 2019 alongside M. Stanley Whittingham and John B. Goodenough.

<span class="mw-page-title-main">Clare Grey</span> British chemist and Professor of Chemistry

Dame Clare Philomena Grey is Geoffrey Moorhouse Gibson Professor in the Department of Chemistry at the University of Cambridge and a Fellow of Pembroke College, Cambridge. Grey uses nuclear magnetic resonance spectroscopy to study and optimize batteries.

Jeff Dahn is a Professor in the Department of Physics & Atmospheric Science and the Department of Chemistry at Dalhousie University. He is recognized as one of the pioneering developers of the lithium-ion battery, which is now used worldwide in laptop computers, cell-phones, cars and many other mobile devices. Although Dr. Dahn made numerous contribution to the development of lithium-ion batteries, his most important discovery was intercalation of Li+ ions into graphite from solvents comprising ethylene carbonate, which was the final piece of the puzzle in the invention of commercial Li-ion battery. Nevertheless, Dahn was not selected for the 2019 Nobel Prize in Chemistry, which recognized only John Goodenough, M. Stanley Whittingham and Akira Yoshino.

Linda Faye Nazar is a Senior Canada Research Chair in Solid State Materials and Distinguished Research Professor of Chemistry at the University of Waterloo. She develops materials for electrochemical energy storage and conversion. Nazar demonstrated that interwoven composites could be used to improve the energy density of lithium–sulphur batteries. She was awarded the 2019 Chemical Institute of Canada Medal.

Deborah Beth Zamble was a Canadian chemist and Canada Research Chair in Biological Chemistry at the University of Toronto. Her research considered how bacteria processed metal nutrients.

Emily D. Cranston is a Canadian chemist who is a professor at the University of British Columbia and President’s Excellence Chair in Forest Bioproducts. She investigates nanocellulose and hybrid bio-based materials. Cranston is an NSERC E.W.R. Steacie fellow and was awarded the Kavli Emerging Leader in Chemistry lectureship in 2018 and the Tappi NanoDivision Technical Award in 2021.

Neil Vasdev is a Canadian and American radiochemist and expert in nuclear medicine and molecular imaging, particularly in the application of PET. Radiotracers developed by the Vasdev Lab are in preclinical use worldwide, and many have been translated for first-in-human neuroimaging studies. He is the director and chief radiochemist of the Brain Health Imaging Centre and director of the Azrieli Centre for Neuro-Radiochemistry at the Centre for Addiction and Mental Health (CAMH). He is the Tier 1 Canada Research Chair in Radiochemistry and Nuclear Medicine, the endowed Azrieli Chair in Brain and Behaviour and Professor of Psychiatry at the University of Toronto. Vasdev has been featured on Global News, CTV, CNN, New York Times, Toronto Star and the Globe and Mail for his innovative research program.

References

  1. ↑ Foss, Kelly (2020-08-28). "Born too soon". Gazette - Memorial University of Newfoundland. Retrieved 2020-08-28.
  2. ↑ "Lindsay Cahill - Google Scholar". scholar.google.ca. Retrieved 2020-08-16.
  3. ↑ Cahill, Lindsay S.; Laliberté, Christine L.; Ellegood, Jacob; Spring, Shoshana; Gleave, Jacqueline A.; van Eede, Matthijs C.; Lerch, Jason P.; Henkelman, R. Mark (2012-04-02). "Preparation of fixed mouse brains for MRI". NeuroImage. 60 (2): 933–939. doi:10.1016/j.neuroimage.2012.01.100. ISSN   1053-8119. PMID   22305951. S2CID   17540273.
  4. ↑ Cahill, Lindsay s. "Solid-state NMR studies of lithium ion dynamics in cathode materials for lithium ion batteries". Dissertation Abstracts International. McMaster University (Canada): 71–05.
  5. ↑ Cahill, L. S.; Chapman, R. P.; Britten, J. F.; Goward, G. R. (April 2006). "7Li NMR and Two-Dimensional Exchange Study of Lithium Dynamics in Monoclinic Li3V2(PO4)3". The Journal of Physical Chemistry B. 110 (14): 7171–7177. doi:10.1021/jp057015+. ISSN   1520-6106. PMID   16599482.
  6. ↑ "MICe - Contact Us". www.mouseimaging.ca. Retrieved 2020-08-16.
  7. ↑ Cahill, Lindsay S.; Zhang, Monan Angela; Ramaglia, Valeria; Whetstone, Heather; Sabbagh, Melika Pahlevan; Yi, Tae Joon; Woo, Laura; Przybycien, Thomas S.; Moshkova, Marina; Zhao, Fei Linda; Rojas, Olga L. (2019-11-05). "Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis". Proceedings of the National Academy of Sciences. 116 (45): 22710–22720. doi: 10.1073/pnas.1915141116 . ISSN   0027-8424. PMC   6842635 . PMID   31641069.
  8. ↑ Newfoundland, Memorial University of. "Department of Chemistry". Memorial University of Newfoundland. Retrieved 2020-08-16.
  9. ↑ Government of Canada, Natural Sciences and Engineering Research Council of Canada (2016-06-28). "NSERC - Research Grants Competition - Results by Institution - 2020". Natural Sciences and Engineering Research Council of Canada (NSERC). Retrieved 2020-08-16.
  10. ↑ Green, Jeff (2020-06-18). "$8-million investment". Gazette - Memorial University of Newfoundland. Retrieved 2020-08-16.
  11. ↑ Green, Jeff (2022-02-22). "Accelerating discoveries". Gazette - Memorial University of Newfoundland. Retrieved 2022-03-22.
  12. ↑ Goulart, Brielle (2022-10-28). "2021 Future Leaders receive $2M from Brain Canada Foundation". Brain Canada. Retrieved 2022-10-31.
  13. ↑ "Lindsay Cahill, PHD".
  14. ↑ Goulart, Brielle (2022-10-28). "2021 Future Leaders receive $2M from Brain Canada Foundation". Brain Canada. Retrieved 2022-10-31.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.