Germany
Baden-Württemberg
- The Lions Eye Bank BW is part of the University Medical Center Freiburg. [9]
North Rhine-Westphalia
- The Lions Eye Bank NRW was established in 1995 and is part of the Universitäts-Augenklinik Düsseldorf.
Lions Eye Bank is the designation given to the various non-profit eye banks operated by member chapters within the Lions Clubs International service organisation. The banks store and prepare donated corneas for transplantation. Corneas may be stored for up to fourteen days [1] before being distributed to an ophthalmic surgeon for transplantation.
There are over 60 Lions Eye Banks around the world, supported as ongoing projects by Lions service clubs. [2]
Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. This may result in blurry vision, double vision, nearsightedness, irregular astigmatism, and light sensitivity leading to poor quality-of-life. Usually both eyes are affected. In more severe cases a scarring or a circle may be seen within the cornea.
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK.
Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue. When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty. Keratoplasty simply means surgery to the cornea. The graft is taken from a recently deceased individual with no known diseases or other factors that may affect the chance of survival of the donated tissue or the health of the recipient.
Eduard Konrad Zirm was an ophthalmologist who performed the first successful human full-thickness corneal transplant on 7 December 1905.
The Lions Eye Institute (LEI) is an Australian medical research institute affiliated with the University of Western Australia. It was established in 1983 with support of the Lions Club of Australia and headquartered in the Perth suburb of Nedlands, Western Australia. The LEI is a not-for-profit centre of excellence that combines an ophthalmic clinic with scientific discovery developing techniques for the prevention of blindness and the reduction of pain from blinding eye conditions.
Eye banks recover, prepare and deliver donated eyes for cornea transplants and research. The first successful cornea transplant was performed in 1905 and the first eye bank was founded in 1944. Currently, in the United States, eye banks provide tissue for over 80,000 cornea transplants each year to treat conditions such as keratoconus and corneal scarring. In some cases, the white of the eye (sclera) is used to surgically repair recipient eyes. Unlike other organs and tissues, there is an adequate supply of corneas for transplants in the United States, and excess tissue is exported internationally, where there are shortages in many countries, due to greater demand and a less-developed eye banking infrastructure.
Descemet's membrane is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea. It is composed of different kinds of collagen than the stroma. The endothelial layer is located at the posterior of the cornea. Descemet's membrane, as the basement membrane for the endothelial layer, is secreted by the single layer of squamous epithelial cells that compose the endothelial layer of the cornea.
Vladimir Petrovich Filatov was a Russian Empire and Soviet ophthalmologist and surgeon best known for his development of tissue therapy. He introduced the tube flap grafting method, corneal transplantation and preservation of grafts from cadaver eyes. He founded the Institute of Eye Diseases & Tissue Therapy in Odessa, Soviet Union. Filatov is also credited for restoring Vasily Zaytsev's sight when he suffered an injury to his eyes from a mortar attack during Battle of Stalingrad.
Keratoglobus is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to become extremely thin and change to a more globular shape than its normal gradual curve. It causes corneal thinning, primarily at the margins, resulting in a spherical, slightly enlarged eye.
Deshabandu Dr F. G. Hudson Silva was the founder and president of the International Eye Bank, Tissue Bank, and the Sri Lanka Eye Donation Society. He was an honorary Fellow of the College of Ophthalmologists of Sri Lanka.
Corneal ulcer is an inflammatory or, more seriously, infective condition of the cornea involving disruption of its epithelial layer with involvement of the corneal stroma. It is a common condition in humans particularly in the tropics and the agrarian societies. In developing countries, children afflicted by Vitamin A deficiency are at high risk for corneal ulcer and may become blind in both eyes, which may persist lifelong. In ophthalmology, a corneal ulcer usually refers to having an infectious cause while the term corneal abrasion refers more to physical abrasions.
Pellucid marginal degeneration (PMD), is a degenerative corneal condition, often confused with keratoconus. It typically presents with painless vision loss affecting both eyes. Rarely, it may cause acute vision loss with severe pain due to perforation of the cornea. It is typically characterized by a clear, bilateral thinning (ectasia) in the inferior and peripheral region of the cornea, although some cases affect only one eye. The cause of the disease remains unclear.
Sri Lanka Eye Donation Society is a non-governmental organization involved in donating human eyes and tissues for transplantation. It serves patients in need both in Sri Lanka and around the world. The society is a non-profit organization and provides the tissues free of charge, except for a small fee on processing and delivery.
David Gregorievich Bushmich was an accomplished ophthalmologist and a leading Soviet eye doctor of his time.
SightLife is an eye bank, a non-profit organization that obtains, medically evaluates and distributes corneas donated by individuals for use in corneal transplantation, research, and education. Since 2009 it has been the leading eye bank in the United States. SightLife provides volunteer services in India, Paraguay and Nepal.
Limbal stem cells, also known as corneal epithelial stem cells, are stem cells located in the basal epithelial layer of the corneal limbus. They form the border between the cornea and the sclera. Characteristics of limbal stem cells include a slow turnover rate, high proliferative potential, clonogenicity, expression of stem cell markers, as well as the ability to regenerate the entire corneal epithelium. Limbal stem cell proliferation has the role of maintaining the cornea; for example, by replacing cells that are lost via tears. Additionally, these cells also prevent the conjunctival epithelial cells from migrating onto the surface of the cornea.
The Legacy Devers Eye Institute in Portland, Oregon, is one of the few private, non-profit centers for ophthalmological care, research, and training in the United States. The institute is affiliated with Legacy Health, a network of seven hospitals in Portland and Southwest Washington. Legacy Devers includes the Thelma and Gilbert Schnitzer Comprehensive Glaucoma Center.
Virender Singh Sangwan is an Indian ophthalmologist and the Dr. Paul Dubord Chair professor and director of the L. V. Prasad Eye Institute, Hyderabad. Known for his research on limbal stem cells, Sangwan is the founder secretary and an adviser of the Uveitis Society of India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2006.
A corneal button is a replacement cornea to be transplanted in the place of a damaged or diseased cornea normally approximately 8.5–9.0mm in diameter. It is used in a corneal transplantation procedure whereby the whole, or part, of a cornea is replaced. The donor tissue can now be held for days to even weeks of the donor's death and is normally a small, rounded shape. The main use of the corneal button is during procedures where the entirety of the cornea needs to be replaced, also known as penetrating keratoplasty.
Herbert Edward Kaufman is an American ophthalmologist who discovered idoxuridine, the first clinically useful antiviral agent; co-developed with William Bourne the clinical specular microscope to view the live corneal endothelium, co-developed timolol with Thomas Zimmerman, a new class of medications to treat glaucoma; corneal storage media for eye banks; natamycin, the first commercially available medication to treat fungal infections of the eye; co-developed with Tony Gasset the use of bandage contact lenses; and was involved in the first laser vision photorefractive keratectomy of the eye with Marguarite McDonald.