Lisa Mirabello

Lisa Mirabello
Alma mater	University at Albany, SUNY, Cornell University, and New York Medical College
Scientific career
Fields	Genetic susceptibility, pediatric cancer, HPV
Institutions	National Cancer Institute

Lisa J. Mirabello is an American medical geneticist who researches genetic susceptibility to pediatric cancer and the genomics of HPV carcinogenicity. She is a senior investigator in the clinical genetics branch at the National Cancer Institute.

Life

Lisa Mirabello earned her Ph.D. in biomedical sciences with a focus on molecular population genetics and infectious disease from the University at Albany, SUNY School of Public Health in 2007. ^[1] Her dissertation was titled, Molecular population genetics of the malaria vector Anopheles darlingi throughout Central and South America using mitochondrial, nuclear, and microsatellite markers. Her dissertation committee members included Jan Conn, Laura D. Kramer, Robert L. Glaser, Gregory Ebel, and Jason Cryan. ^[2] Mirabello joined the clinical genetics branch of the National Cancer Institute's (NCI) division of cancer epidemiology and genetics (DCEG) as a postdoctoral Cancer Genetics research fellow in 2007. ^[1]

Mirabello was promoted to research fellow in 2010 and she was appointed as an Earl Stadtman Investigator in 2013. ^[1] Before that, Mirabello worked as an environmental chemist at Colombia Analytical service in New York from 2000 to 2003. ^[3] She was awarded National Institutes of Health (NIH) scientific tenure and promoted to senior investigator in 2019. ^[1] Mirabello's research program is focused on genetic susceptibility to pediatric cancer and the genomics of HPV carcinogenicity. ^[1] Her most cited work is Osteosarcoma incidence and survival rates from 1973 to 2004, which studied the large differences in incidence and survival rates by age of 3482 patients with osteosarcoma. ^[4] Mirabello has earned a series of accolades over the course of her career, including five DCEG Intramural Research Awards (IRAs) and three NCI Director's Intramural Innovation Awards. ^[5]

Selected works and publications

• Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M.-J., Cullen, M., Epstein, C. G., Burdett, L., Dean, M. C., Chatterjee, N., Sampson, J., Chung, C. C., Kovaks, J., Gapstur, S. M., & Stevens, V. L. (2012). Detectable clonal mosaicism and its relationship to aging and cancer. Nature Genetics, 44(6), 651–658. https://doi.org/10.1038/ng.2270
• Maria Teresa Landi, Chatterjee, N., Yu, K., Goldin, L. R., Goldstein, A. M., Rotunno, M., Mirabello, L., Jacobs, K., William Morton Wheeler, Yeager, M., Bergen, A. W., Li, Q., Consonni, D., Angela Cecilia Pesatori, Sholom Wacholder, Thun, M., Diver, R., Oken, M. M., Jarmo Virtamo, & Albanes, D. (2009). A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. American Society of Human Genetics, 85(5), 679–691. https://doi.org/10.1016/j.ajhg.2009.09.012
• Mirabello, L., Troisi, R. J., & Savage, S. A. (2009). Osteosarcoma incidence and survival rates from 1973 to 2004. Cancer, 115(7), 1531–1543. https://doi.org/10.1002/cncr.24121
• Nelson, C. W., & Mirabello, L. (2023). Human papillomavirus genomics: Understanding carcinogenicity. Tumour Virus Research, 15, 200258. https://doi.org/10.1016/j.tvr.2023.200258
• The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. (2020). Pan-cancer analysis of whole genomes. Nature, 578(7793), 82–93. https://doi.org/10.1038/s41586-020-1969-6
• Wentzensen, I. M., Mirabello, L., Pfeiffer, R. M., & Savage, S. A. (2011). The Association of Telomere Length and Cancer: a Meta-analysis. Cancer Epidemiology Biomarkers & Prevention, 20(6), 1238–1250. https://doi.org/10.1158/1055-9965.epi-11-0005

See also

• List of University at Albany people

References

1. "Lisa Mirabello, Ph.D., biographical sketch and research interests - NCI". dceg.cancer.gov. 2013-09-20. Retrieved 2022-10-18. This article incorporates text from this source, which is in the public domain .
2. Mirabello, Lisa J. (2007). Molecular population genetics of the malaria vector Anopheles darlingi throughout Central and South America using mitochondrial, nuclear, and microsatellite markers (Ph.D. thesis). University at Albany, SUNY. OCLC   304436034.
3. "ORCID". orcid.org. Retrieved 2025-10-08.
4. Mirabello, Lisa; Troisi, Rebecca J.; Savage, Sharon A. (2009). "Osteosarcoma incidence and survival rates from 1973 to 2004". Cancer. 115 (7): 1531–1543. doi:10.1002/cncr.24121. ISSN   1097-0142. PMC   2813207 . PMID   19197972.
5. "Lisa Mirabello, Ph.D. | Principal Investigators | NIH Intramural Research Program". irp.nih.gov. Retrieved 2025-09-24.

 This article incorporates public domain material from websites or documents of the National Institutes of Health.