This is a list of Delaware State Hornets football players in the NFL draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1971 | 3 | 8 | 60 | Steve Davis | Pittsburgh Steelers | RB |
| 1976 | 12 | 18 | 337 | Walter Tullis | Washington Redskins | DB |
| 1983 | 6 | 3 | 143 | Victor Heflin | Denver Broncos | DB |
| 1986 | 3 | 21 | 76 | John Taylor | San Francisco 49ers | WR |
| 1988 | 7 | 26 | 191 | Kevin Bryant | San Francisco 49ers | LB |
| 1989 | 5 | 27 | 139 | Lybrant Robinson | Washington Redskins | DE |
| 1991 | 7 | 10 | 177 | David Jones | San Diego Chargers | WR |
| 1992 | 5 | 9 | 121 | Rod Milstead | Dallas Cowboys | G |
| 2001 | 5 | 23 | 154 | Darnerien McCants | Washington Redskins | WR |
| 2015 | 4 | 17 | 116 | Rodney Gunter | Arizona Cardinals | DT |