| Minister | Position | Year Appointed | Administration |
|---|
| Government |
| Tsai Ing-wen | President of the Republic of China | 2016 | Herself |
| Annette Lu | Vice President of the Republic of China | 2000 | Chen Shui-bian |
| Chang Po-ya | President of the Control Yuan | 2014 | Ma Ying-jeou |
| Chen Chu | President of the Control Yuan | 2020 | Tsai Ing-wen |
| Minister of Culture |
| Lung Ying-tai | Minister of Culture | 2012 | Ma Ying-jeou |
| Cheng Li-chun | Minister of Culture | 2016 | Tsai Ing-wen |
| Minister of Economic Affairs |
| Christine Tsung | Minister of Economic Affairs | 2002 | Chen Shui-bian |
| Ho Mei-yueh | Minister of Economic Affairs | 2004 | Chen Shui-bian |
| Wang Mei-hua | Minister of Economic Affairs | 2020 | Tsai Ing-wen |
| Minister of Finance |
| Shirley Kuo | Minister of Finance | 1988 | Lee Teng-hui |
| Christina Liu | Minister of Finance | 2012 | Ma Ying-jeou |
| Chuang Tsui-yun | Minister of Finance | 2023 | Tsai Ing-wen |
| Minister of Health and Welfare |
| Chang Po-ya | Minister of the Department of Health | 1990 | Lee Teng-hui |
| Minister of Interior |
| Yeh Chin-fong | Minister of Interior | 1997 | Lee Teng-hui |
| Chang Po-ya | Minister of Interior | 2000 | Chen Shui-bian |
| Liu Shyh-fang | Minister of Interior | 2024 | Lai Ching-tai |
| Minister of Justice |
| Yeh Chin-fong | Minister of Justice | 1999 | Lee Teng-hui |
| Wang Ching-feng | Minister of Justice | 2008 | Ma Ying-jeou |
| Luo Ying-shay | Minister of Justice | 2013 | Ma Ying-jeou |
| Minister of Labor |
| Chen Chu | Minister of the Council of Labor Affairs | 2000 | Chen Shui-bian |
| Wang Ju-hsuan | Minister of the Council of Labor Affairs | 2008 | Ma Ying-jeou |
| Lin Mei-chu | Minister of Labor | 2017 | Tsai Ing-wen |
| Hsu Ming-chun | Minister of Labor | 2018 | Tsai Ing-wen |
| Ministry of Transport and Communications |
| Yeh Chu-lan | Minister of Transport and Communications | 2000 | Chen Shui-bian |
| Kuo Yao-chi | Minister of Transport and Communications | 2006 | Chen Shui-bian |
| Minister without Portfolio |
| Yeh Chin-fong | Minister without Portfolio | 1996 | Lee Teng-hui |
| Shirley Kuo Wang-jung | Minister without Portfolio | 1998 | Lee Teng-hui |
| Yan Chung Chin | Minister without Portfolio | 2000 | Chen Shui-bian |
| Kuo Yao-chi | Minister without Portfolio | 2002 | Chen Shui-bian |
| Fu Li-yeh | Minister without Portfolio | 2004 | Chen Shui-bian |
| Ho Mei-yueh | Minister without Portfolio | 2006 | Chen Shui-bian |
| Luo Ying-shay | Minister without Portfolio | 2011 | Ma Ying-jeou |
| Central Election Commission |
| Chang Po-ya | Chairperson of Central Election Commission | 2010 | Ma Ying-jeou |
| Mongolian and Tibetan Affairs Commission |
| Luo Ying-shay | Minister of Mongolian and Tibetan Affairs Commission | 2011 | Ma Ying-jeou |
| Jaclyn Tsai | Minister of Mongolian and Tibetan Affairs Commission | 2013 | Ma Ying-jeou |
|
| National Communications Commission |
| Chan Ting-I | Chairperson of National Communications Commission | 2016 | Tsai Ing-wen |
| Council for Economic Planning and Development |
| Shirley Kuo Wang-jung | Minister of the Council for Economic Planning and Development | 1993 | Lee Teng-hui |
| Ho Mei-yueh | Minister of the Council for Economic Planning and Development | 2007 | Chen Shui-bian |
| Christina Liu | Minister of the Council for Economic Planning and Development | 2010 | Ma Ying-jeou |
| Hakka Affairs Council |
| Yeh Chu-lan | Minister of the Hakka Affairs Council | 2002 | Chen Shui-bian |
| Chung Wan-mei | Minister of the Hakka Affairs Council | 2016 | Ma Ying-jeou |
| Mainland Affairs Council |
| Tsai Ing-wen | Minister of the Mainland Affairs Council | 2000 | Chen Shui-bian |
| Lai Shin-yuan | Minister of the Mainland Affairs Council | 2008 | Ma Ying-jeou |
| Katharine Chang | Minister of the Mainland Affairs Council | 2016 | Tsai Ing-wen |
| Overseas Community Affairs Council |
| Chang Fu-mei | Minister of the Overseas Compatriot Affairs Commission | 2000 | Chen Shui-bian |
| Directorate-General of Budget, Accounting and Statistics |
| Shih Su-mei | Minister of Directorate-General of Budget, Accounting and Statistics | 2008 | Ma Ying-jeou |
| Government Information Office |
| Chung Chin | Minister of Government Information Office | 2000 | Chen Shui-bian |
| Vanessa Shih | Minister of Government Information Office | 2008 | Ma Ying-jeou |