Fourteen people have served as Minister for Home Affairs of Malta since the office was established in 1976.
- Political parties
Labour Party Nationalist Party
| Minister for Home Affairs | Term of office | Political party | ||||
|---|---|---|---|---|---|---|
| No. | Portrait | Name (Birth–Death) | No. | Took office | Left office | |
| 1 |  | Dom Mintoff (1916–2012) | 1st | 25 September 1976 | 20 December 1981 | Labour Party |
| 2 |  | Lorry Sant (1937–1995) | 20 December 1981 | 3 September 1983 | Labour Party | |
| (1) | | Dom Mintoff (1916–2012) | 2nd | 3 September 1983 | 22 December 1984 | Labour Party |
| 3 |  | Karmenu Mifsud Bonnici (1933–) | 22 December 1984 | 12 May 1987 | Labour Party | |
| 4 |  | Guido de Marco (1931–2010) | 12 May 1987 | 5 May 1990 | Nationalist Party | |
| 5 |  | Ugo Mifsud Bonnici (1932–) | 5 May 1990 | 27 February 1992 | Nationalist Party | |
| 6 | | Louis Galea (1948–) | 27 February 1992 | 1 April 1995 | Nationalist Party | |
| 7 |  | Tonio Borg (1957–) | 1st | 1 April 1995 | 28 October 1996 | Nationalist Party |
| 8 |  | Alfred Sant (1948–) | 29 October 1996 | 6 September 1998 | Labour Party | |
| (7) | | Tonio Borg (1957–) | 2nd | 8 September 1998 | 12 March 2008 | Nationalist Party |
| 9 | | Carmelo Mifsud Bonnici (1960–) | 12 March 2008 | 30 May 2012 | Nationalist Party | |
| 10 |  | Lawrence Gonzi (1953–) | 30 May 2012 | 13 March 2013 | Nationalist Party | |
| 11 |  | Emmanuel Mallia (–) | 13 March 2013 | 9 December 2014 | Labour Party | |
| 12 |  | Carmelo Abela (1972–) | 9 December 2014 | 9 June 2017 | Labour Party | |
| 13 | Michael Farrugia | 9 June 2017 | 13 January 2020 | Labour Party | ||
| 14 | Byron Camilleri (1988–) | 15 January 2020 | Incumbent | Labour Party | ||