M. Lisa Manning

Last updated
M. Lisa Manning
Born(1980-09-05)September 5, 1980
Cincinnati, Ohio, United States
NationalityAmerican
SpouseWilliam Wylie
Awards Sloan Research Fellowship
Simons Investigators Award
Maria Goeppert-Mayer Award
Scientific career
Thesis Effective temperature and strain localization in amorphous solids  (2004)
Doctoral advisor Jean Carlson
Website https://mmanning.expressions.syr.edu

Mary Lisa Manning (born 1980) is an American physicist and the William R. Kenan, Jr., Professor [1] of Physics at Syracuse University in Syracuse, New York, United States. Manning's research focuses on the behavior of glassy materials, using simulations and theory to model the emergent properties of biological tissues.

Contents

Background

Manning grew up in kentucky, near Cincinnati, Ohio and attended the University of Virginia as a Jefferson Scholar, graduating in 2002 with bachelor's degrees in physics and mathematics. [2] [3] She earned a Ph.D. in physics from the University of California at Santa Barbara in 2008, followed by a postdoctoral fellowship at the Princeton University Center for Theoretical Science. In 2011, Manning accepted a faculty position at Syracuse University. In 2020, Manning was named the William R. Kenan, Jr., Professor [1] of Physics at the same university.

Manning is married to William Wylie and has two children. [3]

Research

As a graduate student, Manning studied the behaviors and properties of disordered solids and glasses under the mentorship of Jean Carlson. Among other findings, she described how effective temperature is an important determinant of material failure and strain localization, with potential applications for a wide range of amorphous materials. [4]

After earning her Ph.D., Manning expanded her research on amorphous and granular solids to include biological cells, noting that many types of tissues behave as though they were glassy solids. [5] Manning has developed a model describing the relationship between cell adhesion and cortical tension as a determinant for embryonic surface tension. [6] Her ongoing research modeling the relationship between cell shape and jamming leading to tissue rigidity has implications for cell migration in metastatic cancer, wound healing, embryogenesis, and asthma. [7] [8] [9] [10] [11] In addition, Manning has continued to explore the dynamics of conventional disordered solids. [12] [13] [14] In 2018, Manning was named by Science News as one of 2018's 10 scientists to watch. [15]

Honors and awards

Related Research Articles

In condensed matter physics and materials science, an amorphous solid is a solid that lacks the long-range order that is characteristic of a crystal. The terms "glass" and "glassy solid" are sometimes used synonymously with amorphous solid; however, these terms refer specifically to amorphous materials that undergo a glass transition. Examples of amorphous solids include glasses, metallic glasses, and certain types of plastics and polymers.

<span class="mw-page-title-main">Amorphous metal</span> Solid metallic material with disordered atomic-scale structure

An amorphous metal is a solid metallic material, usually an alloy, with disordered atomic-scale structure. Most metals are crystalline in their solid state, which means they have a highly ordered arrangement of atoms. Amorphous metals are non-crystalline, and have a glass-like structure. But unlike common glasses, such as window glass, which are typically electrical insulators, amorphous metals have good electrical conductivity and can show metallic luster.

Chalcogenide glass is a glass containing one or more heavy chalcogens. Chalcogenide materials behave rather differently from oxides, in particular their lower band gaps contribute to very dissimilar optical and electrical properties.

Amorphous calcium phosphate (ACP) is a glassy solid that is formed from the chemical decomposition of a mixture of dissolved phosphate and calcium salts (e.g. (NH4)2HPO4 + Ca(NO3)2). The resulting amorphous mixture consists mostly of calcium and phosphate, but also contains varying amounts of water and hydrogen and hydroxide ions, depending on the synthesis conditions. Such mixtures are also known as calcium phosphate cement.

<span class="mw-page-title-main">Jamming (physics)</span>

Jamming is the physical process by which the viscosity of some mesoscopic materials, such as granular materials, glasses, foams, polymers, emulsions, and other complex fluids, increases with increasing particle density. The jamming transition has been proposed as a new type of phase transition, with similarities to a glass transition but very different from the formation of crystalline solids.

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Rigidity theory, or topological constraint theory, is a tool for predicting properties of complex networks based on their composition. It was introduced by James Charles Phillips in 1979 and 1981, and refined by Michael Thorpe in 1983. Inspired by the study of the stability of mechanical trusses as pioneered by James Clerk Maxwell, and by the seminal work on glass structure done by William Houlder Zachariasen, this theory reduces complex molecular networks to nodes constrained by rods, thus filtering out microscopic details that ultimately don't affect macroscopic properties. An equivalent theory was developed by P. K. Gupta and A. R. Cooper in 1990, where rather than nodes representing atoms, they represented unit polytopes. An example of this would be the SiO tetrahedra in pure glassy silica. This style of analysis has applications in biology and chemistry, such as understanding adaptability in protein-protein interaction networks. Rigidity theory applied to the molecular networks arising from phenotypical expression of certain diseases may provide insights regarding their structure and function.

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Bulbul Chakraborty is the Enid and Nate Ancell Professor of Physics at Brandeis University. She is recognized for her contributions to soft condensed matter theory studying systems far from equilibrium, such as granular materials, amorphous systems, and statistical physics. She is an elected American Physical Society and American Association for the Advancement of Science fellow.

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References

  1. 1 2 "M. Lisa Manning, professor of physics and founding director of BioInspired Syracuse: Institute for Material and Living Systems, has been named the William R. Kenan, Jr., Professor of Physics. This highly selective professorship was established in 1971 by". College of Arts & Sciences at Syracuse University. Retrieved 2020-06-22.
  2. ↑ "Lisa Manning - Jefferson Scholars Foundation". www.jeffersonscholars.org.
  3. 1 2 Morelli, Marie (19 June 2024). "M. Lisa Manning on leadership: Give people 'the freedom to work on things and the freedom to fail'". syracuse.com . Retrieved 19 June 2024.
  4. ↑ Effective temperature and strain localization in amorphous solids (PhD thesis). University of California, Santa Barbara. ISBN   9780549842576 . Retrieved 2022-09-01.
  5. ↑ "The Physics of Glass Opens a Window Into Biology - Quanta Magazine". 11 June 2018.
  6. ↑ Manning, M. Lisa; Foty, Ramsey A.; Steinberg, Malcolm S.; Schoetz, Eva-Maria (13 July 2010). "Coaction of intercellular adhesion and cortical tension specifies tissue surface tension". Proceedings of the National Academy of Sciences. 107 (28): 12517–12522. Bibcode:2010PNAS..10712517M. doi: 10.1073/pnas.1003743107 . PMC   2906578 . PMID   20616053.
  7. ↑ Merkel, Matthias; Manning, Lisa (2017). "A geometrically controlled rigidity transition in a model for confluent 3D tissues". New Journal of Physics. 20 (2): 022002. arXiv: 1706.02656 . doi:10.1088/1367-2630/aaaa13. S2CID   3867697.
  8. ↑ Merkel, Matthias; Manning, Lisa; Schwarz, J. M.; Manning, M. Lisa (2013). "Energy barriers govern glassy dynamics in tissues". Soft Matter. 10 (12): 1885–90. arXiv: 1308.3891 . doi:10.1039/c3sm52893f. PMID   24652538.
  9. ↑ Amack, Jeffrey D.; Manning, M. Lisa (12 October 2012). "Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting". Science. 338 (6104): 212–215. Bibcode:2012Sci...338..212A. doi:10.1126/science.1223953. PMID   23066072. S2CID   206542264.
  10. ↑ Yang, Xingbo; Bi, Dapeng; Czajkowski, Michael; Merkel, Matthias; Manning, M. Lisa; Marchetti, M. Cristina (28 November 2017). "Correlating cell shape and cellular stress in motile confluent tissues". Proceedings of the National Academy of Sciences. 114 (48): 12663–12668. arXiv: 1704.05951 . Bibcode:2017PNAS..11412663Y. doi: 10.1073/pnas.1705921114 . PMC   5715741 . PMID   29138312.
  11. ↑ "Jammed Cells Expose the Physics of Cancer". Quanta Magazine. 16 August 2016.
  12. ↑ Merkel, Matthias; Manning, Lisa (2015). "Disentangling defects and sound modes in disordered solids". arXiv: 1502.00685 [cond-mat.soft].
  13. ↑ Merkel, Matthias; Manning, Lisa; Porter, M. A; Manning, M. L; Daniels, K. E (2015). "Extraction of Force-Chain Network Architecture in Granular Materials Using Community Detection". Soft Matter. 11 (14): 2731–44. arXiv: 1408.3841 . Bibcode:2015SMat...11.2731B. doi:10.1039/c4sm01821d. PMID   25703651. S2CID   18154269.
  14. ↑ Merkel, Matthias; Manning, Lisa (2015). "A random matrix definition of the boson peak". EPL. 109 (36002): 36002. arXiv: 1307.5904 . Bibcode:2015EL....10936002M. doi:10.1209/0295-5075/109/36002. S2CID   21737384.
  15. ↑ Cunningham, Aimee (28 September 2018). "Lisa Manning describes the physics of how cells move".
  16. ↑ "Materials, like metallic glass, can help us understand how cells break - NSF - National Science Foundation". www.nsf.gov.
  17. ↑ "Immersive DNA force sensors and predictive mechanical modeling for tissue morphogenesis - Scialog: Collaborative Teams - Research Corporation for Science Advancement". Research Corporation for Science Advancement.
  18. ↑ "M. Lisa Manning - Cottrell Scholar Awards - Research Corporation for Science Advancement". Research Corporation for Science Advancement.
  19. ↑ "Lisa Manning - Simons Foundation". Simons Foundation. 13 July 2017.
  20. ↑ "C3: News - IUPAP: The International Union of Pure and Applied Physics". iupap.org. 8 March 2021.
  21. ↑ "2018 Stanley Corrsin Award Recipient". www.aps.org.
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