MCL may refer to:
Leukemia is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy.
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes. Early on, there are typically no symptoms. Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. Enlargement of the spleen and low red blood cells (anemia) may also occur. It typically worsens gradually over years.
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. As an acute leukemia, ALL progresses rapidly and is typically fatal within weeks or months if left untreated.
HCL may refer to:
Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. This includes multiple myeloma in those who have and have not previously received treatment. It is generally used together with other medications. It is given by injection.
The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by G-CSF and other cytokines triggers maturation, differentiation, proliferation and cell survival.
T-cell leukemia describes several different types of lymphoid leukemia which affect T cells.
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. Occasionally, spread may occur to the brain, skin, or gums. As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated.
MCL Restaurant & Bakery, formerly known as MCL Cafeterias, is a chain of American cafeteria-style restaurants based in Indianapolis. As of April 2024, the company operates 13 locations in Illinois, Indiana, and Ohio.
Mantle cell lymphoma (MCL) is a type of non-Hodgkin's lymphoma, comprising about 6% of cases. It is named for the mantle zone of the lymph nodes where it develops. The term 'mantle cell lymphoma' was first adopted by Raffeld and Jaffe in 1991.
Induced myeloid leukemia cell differentiation protein Mcl-1 is a protein that in humans is encoded by the MCL1 gene.
ATL may refer to:
Myeloid leukemia is a type of leukemia affecting myeloid tissue.
Ibrutinib, sold under the brand name Imbruvica among others, is a small molecule drug that inhibits B-cell proliferation and survival by irreversibly binding the protein Bruton's tyrosine kinase (BTK). Blocking BTK inhibits the B-cell receptor pathway, which is often aberrantly active in B cell cancers. Ibrutinib is therefore used to treat such cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia. Ibrutinib also binds to C-terminal Src Kinases. These are off-target receptors for the BTK inhibitor. Ibrutinib binds to these receptors and inhibits the kinase from promoting cell differentiation and growth. This leads to many different side effects like left atrial enlargement and atrial fibrillation during the treatment of Chronic Lymphocytic Leukemia.
Moroto Cement Limited (MCL), whose full name is Moroto Cement Industries Limited, is a manufacturer of cement in Uganda with approximately 3000 tonnes per day clinker capacity.
Mysore Cements Limited is one of major producers of Cement in south India since its establishment in 1958 – 59 by Karnataka-based industrialist Sarangapani Mudaliar and by collaboration of Kaisers USA as a Public Limited Company The company produced its major output of 1 ton cement with the investment of about 20 million Rupees, in 1962. MCL was immediately taken over by Kaisers and G.D Birla and from then the following years company started producing more cement and it was 4 tpa by the end of year 1968. With an investment of 23 million, MCL produced 6 tpa of cement in Ammasandra unit Based in Tumkur District of Karnataka State. After the death of G.D Birla, in 1983 MCL was totally under control of Birlas and Shri. S.K Birla, grandson of GD Birla was declared the chairman of the organisation.
Acalabrutinib, sold under the brand name Calquence, is a medication used to treat various types of non-Hodgkin lymphoma, including mantle cell lymphoma (MCL) and chronic lymphocytic leukemia/small lymphocytic Lymphoma (CLL/SLL). It may be used both in relapsed as well as in treatment-naive settings.
Chakradharpur railway division is one of the four railway divisions under South Eastern Railway zone of Indian Railways. This railway division was formed on 14 April 1952 and its headquarter is located at Chakradharpur in West Singhbhum district of the state of Jharkhand of India.
Malabar Cements Limited is an Indian cement company. It is among the largest public sector cement production undertakings. It is fully owned by the Government of Kerala and is the only major integrated cement plant in the State. The total installed capacity of MCL is 6.2 lakh tons. This ISO 9001:2000 company is responsible for about 10% of total cement production in Kerala.
Mombasa Cement Limited0706/01/85/07 (MCL) is an industrial company in Kenya specializing in the manufacture of construction materials. The company maintains its headquarters in the city of Mombasa and has offices and warehouses in Nairobi, with manufacturing plants in Athi River in Machakos County and in Vipingo, in Kilifi County. According to its website, as of May 2022, MCL had installed production capacity of 3.3 million metric tonnes of cement annually. The privately owned business markets its products under the NYUMBA brand.