MYL12B

Myosin, light chain 12B, regulatory is a protein that in humans is encoded by the MYL12B gene. ^[1] The gene is also known as MLC-B and MRLC2. ^[1] The activity of nonmuscle myosin II is regulated by phosphorylation of a regulatory light chain, such as MYL12B. This phosphorylation results in higher ATPase activity and the assembly of myosin II filaments. ^{[1] [2]}

References

1. "Myosin, light chain 12B, regulatory" . Retrieved 2011-12-05.
2. Iwasaki, T.; Murata-Hori, M.; Ishitobi, S.; Hosoya, H. (2001). "Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells". Cell Structure and Function. 26 (6): 677–683. doi: 10.1247/csf.26.677 . PMID   11942626.

Further reading

• Li, T. B.; Liu, X. H.; Feng, S.; Hu, Y.; Yang, W. X.; Han, Y.; Wang, Y. G.; Gong, L. M. (2004). "Characterization of MR-1, a novel myofibrillogenesis regulator in human muscle". Acta Biochimica et Biophysica Sinica. 36 (6): 412–418. doi:10.1093/abbs/36.6.412. PMID   15188056. S2CID   18331104.