Marcus Conant | |
---|---|
Born | |
Nationality | American |
Education | B.S. in Zoology from Duke University in 1957, Graduated from Duke Medical School in 1961 |
Occupation | Chief Medical Officer at American Gene Technologies |
Known for | Identification of Kaposi's Sarcoma in AIDS patients |
Parent(s) | Marcus Conant (Father), Annie Long Conant (Mother) |
Marcus Augustine Conant (born May 11, 1936, in Jacksonville, Florida) is an American dermatologist and one of the first physicians to diagnose and treat Acquired Immune Deficiency Syndrome (AIDS) in 1981. He helped create one of the largest private AIDS clinics, was a founder of the San Francisco AIDS Foundation, and his work contributed to development of some of today's top HIV medications. He has written over 70 publications on the treatment of AIDS. [1]
Marcus Augustine Conant was born on May 11, 1936, in Jacksonville, Florida, to Marcus and Annie Long Conant. His father was in the military, leading to Marcus moving around a lot during his early years. [2] When his father was deployed to Europe, Marcus and his family moved back to Jacksonville, Florida where he attended high school. [2] Conant then attended Duke University where he graduated in 1957 with a B.S. in Zoology. In 1961, Conant graduated from Duke University College of Medicine with a specialty in Dermatology and interned at Duke University Medical Center. Conant served in the United States Air Force as a flight surgeon, on active duty from 1962 to 1964, and continuing as a reservist until 1967.
In 1964, Conant joined the University of California San Francisco Medical Center as a dermatology resident. [3] In 1967, he received his first academic appointment, as an instructor in clinical dermatology. As a resident at UCSF, Conant also volunteered at the Haight Ashbury Free Clinics, where he treated patients with genital herpes. [4] Over the years, Conant rose up the academic ladder, and in 1984, he was appointed as clinical professor of dermatology.
While he was an associate professor at UCSF, Conant first identified Kaposi's Sarcoma and AIDS in patients, [5] [6] including early AIDS activist Bobbi Campbell. [7] Conant founded the Kaposi's Sarcoma Research & Education Foundation in May 1982, which quickly became the first multidisciplinary AIDS clinic, and is now known today as the San Francisco AIDS Foundation. [2] [8] In 1987, Conant was appointed as co-chair of the California AIDS Leadership Committee, where he created California's initial policies in response to the AIDS epidemic. [9]
He was the lead plaintiff in the Walters vs. Conant trial, which lead to the judicial decision protecting the First Amendment right of physicians to recommend the use of medical marijuana to people living with HIV and AIDS, as well as the right to talk to their patients about anything as long as it was in the privacy of the examination room. [10] [11]
In 2010, Conant closed his practice in San Francisco, where he cared for over 8,000 patients with HIV/AIDS, and moved to New York, citing rising costs and difficulties in dealing with health insurance companies. [3] He stated, "I'm sorry to have to leave my patients, and a lot of them are sorry I had to leave, but it's time. This is only symptomatic of a much bigger problem we have in this country with health care." He continued to consult with researchers on a reported association of a virus with chronic fatigue syndrome and autism. [12]
In August 2021, Conant was appointed as a special advisor to the CEO at American Gene Technologies (AGT), a biotechnology company in Rockville, Maryland who is focused on using gene therapy to find a cure for a variety of diseases, including HIV. [13] Conant was eventually moved up to the role of Chief Medical Officer (CMO) at American Gene Technologies in October 2021, where he oversees the clinical trials for AGT's potential HIV cure therapy, AGT103-T. [14]
Gaëtan Dugas was a Québécois Canadian flight attendant and a relatively early patient with the human immunodeficiency virus (HIV), who once was widely described as "Patient Zero", accusing him of introducing HIV to the United States. This claim has since been proven incorrect.
Randy Shilts was an American journalist and author. After studying journalism at the University of Oregon, Shilts began working as a reporter for both The Advocate and the San Francisco Chronicle, as well as for San Francisco Bay Area television stations. In the 1980s, he was noted for being the first openly gay reporter for the San Francisco Chronicle.
Michael Callen was an American singer, songwriter, composer, author, and AIDS activist. Callen was diagnosed with AIDS in 1982 and became a pioneer of AIDS activism in New York City, working closely with his doctor, Dr. Joseph Sonnabend, and Richard Berkowitz. Together, they published articles and pamphlets to raise awareness about the correlation between risky sexual behaviors and AIDS.
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is Human gammaherpesvirus 8, or HHV-8 in short. Like other herpesviruses, its informal names are used interchangeably with its formal ICTV name. This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients, as well as primary effusion lymphoma, HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome. It is one of seven currently known human cancer viruses, or oncoviruses. Even after many years since the discovery of KSHV/HHV8, there is no known cure for KSHV associated tumorigenesis.
This is a timeline of HIV/AIDS, including cases before 1980.
Robert Boyle "Bobbi" Campbell Jr. was a public health nurse and an early United States AIDS activist. In September 1981, Campbell became the 16th person in San Francisco to be diagnosed with Kaposi's sarcoma, when that was a proxy for an AIDS diagnosis. He was the first to come out publicly as a person with what came to be known as AIDS, writing a regular column in the San Francisco Sentinel, syndicated nationwide, describing his experiences and posting photos of his KS lesions to help other San Franciscans know what to look for, as well as helping write the first San Francisco safer sex manual.
Cleve Jones is an American AIDS and LGBT rights activist. He conceived the NAMES Project AIDS Memorial Quilt, which has become, at 54 tons, the world's largest piece of community folk art as of 2020. In 1983 at the onset of the AIDS pandemic, Jones co-founded the San Francisco AIDS Foundation, which has grown into one of the largest and most influential advocacy organizations empowering people with AIDS in the United States.
And the Band Played On is a 1993 American television film docudrama directed by Roger Spottiswoode. The teleplay by Arnold Schulman is based on the best-selling 1987 non-fiction book And the Band Played On: Politics, People, and the AIDS Epidemic by Randy Shilts, and is noteworthy for featuring both a vast historical scope, as well as an exceptionally sprawling cast.
Robert Allen Schwartz is an American physician, biomedical researcher, university professor, and government official. He is Professor and Head of Dermatology, Professor of Medicine, Professor of Pediatrics, and Professor of Preventive Medicine and Community Health at the Rutgers New Jersey Medical School, Visiting Professor and Scholar of Public Affairs and Administration at the Rutgers School of Public Affairs and Administration, and serves on the Rutgers University Board of Trustees. He has made seminal contributions to medicine, including the discovery of AIDS-associated Kaposi sarcoma (KS-AIDS) and Schwartz–Burgess syndrome. In 2019 Schwartz joined the Trump administration as a member of the Presidential Advisory Council on HIV/AIDS.
Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, in lymph nodes, in the mouth, or in other organs. The skin lesions are usually painless, purple and may be flat or raised. Lesions can occur singly, multiply in a limited area, or may be widespread. Depending on the sub-type of disease and level of immune suppression, KS may worsen either gradually or quickly. Except for Classical KS where there is generally no immune suppression, KS is caused by a combination of immune suppression and infection by Human herpesvirus 8.
Sue Desmond-Hellmann is an American oncologist and biotechnology leader who served as the Chief Executive Officer of the Bill & Melinda Gates Foundation from 2014 to 2020. She was previously Chancellor of the University of California, San Francisco (UCSF), the first woman to hold the position, and Arthur and Toni Rembe Rock Distinguished Professor, and before that president of product development at Genentech, where she played a role in the development of the first gene-targeted cancer drugs, Avastin and Herceptin.
Arnold William Klein was an American dermatologist.
Selma Kaderman Dritz was an American physician and epidemiologist who worked in San Francisco, California, where she began tracking the first known cases of Acquired Immune Deficiency Syndrome (AIDS) in the early 1980s.
And the Band Played On: Politics, People, and the AIDS Epidemic is a 1987 book by San Francisco Chronicle journalist Randy Shilts. The book chronicles the discovery and spread of the human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) with a special emphasis on government indifference and political infighting—specifically in the United States—to what was then perceived as a specifically gay disease. Shilts's premise is that AIDS was allowed to happen: while the disease is caused by a biological agent, incompetence and apathy toward those initially affected allowed its spread to become much worse.
Michael Stuart Gottlieb is an American physician and immunologist known for his 1981 identification of acquired immune deficiency syndrome (AIDS) as a new disease, and for his HIV/AIDS research, HIV/AIDS activism, and philanthropic efforts associated with HIV/AIDS treatment.
Linda Jane Laubenstein was an American physician and early HIV/AIDS researcher. She was among the first doctors in the United States to recognize the AIDS epidemic of the early 1980s; she co-authored the first article linking AIDS with Kaposi's sarcoma.
Sandy Ford was a drug technician for the Centers for Disease Control in Atlanta, Georgia. In April 1981, she identified unusual clusters of young homosexual patients in New York and California with pneumocystis pneumonia and Kaposi's sarcoma and alerted her supervisor about it. Those patients had HIV/AIDS; pneumocystis pneumonia and Kaposi's sarcoma were later found to be AIDS-defining diseases.
The San Francisco AIDS Foundation (SFAF) is a nonprofit organization dedicated to providing services for people with HIV/AIDS, with a mission to end the AIDS epidemic in the United States. They were founded in 1982, at the beginning of the AIDS epidemic. SFAF is one of the largest and oldest community-based AIDS service organizations in the United States. SFAF has an 87.67% overall rating, and a 97% accountability & transparency rating, at Charity Navigator.
New York City was affected by the AIDS epidemic of the 1980s more than any other U.S. city. The AIDS epidemic has been and continues to be highly localized due to a number of complex socio-cultural factors that affect the interaction of the populous communities that inhabit New York.
Esther Ellen Freeman is an American physician who is an Assistant Professor of Dermatology at the Harvard Medical School and Director of Global Health Dermatology at Massachusetts General Hospital. Her research considers HIV infection with AIDS-defining malignancies, including Kaposi's sarcoma. During the COVID-19 pandemic Freeman established the American Academy of Dermatology register of COVID-19 skin complaints, through which she identified the novel symptom of COVID toes.