Sir Mark Jonathan Caulfield (born 19 July 1960) MD, FRCP, FESC, FPharm, FBHS, FMedSci, is a British genomic medicine researcher and Warden of Barts and The London School of Medicine and Dentistry. He is the Professor of Clinical Pharmacology at the William Harvey Research Institute in Queen Mary University of London. He was awarded a knighthood in the 2019 Birthday Honours.
Caulfield was born in 1960. His Irish parents raised him in North London. [1] He attended Bishop Douglass School in Finchley and London Hospital Medical College where he graduated with a degree in medicine in 1984. [2] With his medical degree, Caulfield trained at St Bartholomew's Hospital where he developed a research programme in molecular genetics of hypertension. [3]
In 2002, Caulfield was appointed as the Director of the William Harvey Research Institute at Queen Mary University of London. [4] While there, he was elected to the Academy of Medical Sciences [5] and awarded the Lilly Prize of the British Pharmacological Society. [4] From 2009 until 2011, Caulfield also served as President of the British Hypertension Society, while also directing the National Institute for Health Research (NIHR) Bart’s Biomedical Research Centre. [4]
In 2013, Caulfield was appointed as Chief Scientist for Genomics England, a non-profit company run through the Department of Health. [6] He was charged with the scientific strategic oversight and delivery of the 100,000 Genomes Project which is a healthcare transformation applying whole genome sequencing to rare disease, cancer, and infection. ". [1]
By 2014, Caulfield was reported to be a Highly Cited Researcher as determined by Thomson Reuters. [7] A few years later, he received the Franz Volhard Award and Lectureship for Outstanding Research by the International Society of Hypertension. [8] By 2018, Caulfield was reported to be one the top “influential researchers” in the world. [9]
Caulfield was awarded a knighthood in the 2019 Birthday Honours. [10] He also agreed to act as interim Chief Executive of Genomics England following the department of John Mattick. [11]
In 2022, Sir Mark was appointed as Vice-Principal Health for Queen Mary, University of London. He is also the Warden of Bart’s and The London School of Medicine and Dentistry. [12]
Caulfield married his wife Fran in 1991 and they have two daughters together. Sarah studied at University of Nottingham and is a practising Veterinary Surgeon, and Rachel studied Medicine at University of Bristol. [1] In a June 2017 interview he claimed to be a workaholic with few hobbies, aside from walking, particularly in Germany, playing golf "badly" and gardening "often unsuccessfully". [1]
Sir James Whyte Black was a Scottish physician and pharmacologist. Together with Gertrude B. Elion and George H. Hitchings, he shared the Nobel Prize for Medicine in 1988 for pioneering strategies for rational drug-design, which, in his case, lead to the development of propranolol and cimetidine. Black established a Veterinary Physiology department at the University of Glasgow, where he became interested in the effects of adrenaline on the human heart. He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment of heart disease. Black was also responsible for the development of cimetidine, an H2 receptor antagonist, a drug used to treat stomach ulcers.
Queen Mary University of London is a public research university in Mile End, East London, England. It is a member institution of the federal University of London.
Barts and The London School of Medicine and Dentistry, commonly known as Barts or BL, is a medical and dental school in London, England. The school is part of Queen Mary University of London, a constituent college of the federal University of London, and the United Hospitals. It was formed in 1995 by the merger of the London Hospital Medical College and the Medical College of St Bartholomew's Hospital.
Sir John Robert Vane was a British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. He was awarded the Nobel Prize in Physiology or Medicine in 1982 along with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances".
Frances Rosemary Balkwill is an English scientist, Professor of Cancer Biology at Queen Mary University of London, and author of children's books about scientific topics.
Dame Anna Felicja Dominiczak DBE FRCP FRSE FAHA FMedSci is a Polish-born British medical researcher, Regius Professor of Medicine - the first woman to hold this position, and the Chief Scientist (Health) for the Scottish Government. From 2010 to 2020, Dominiczak was the Vice-Principal and Head of the College of Medical, Veterinary and Life Sciences at the University of Glasgow, Scotland. She is an Honorary Consultant Physician and Endocrinologist for the NHS Greater Glasgow and Clyde Health Board, and Health Innovation Champion for the Medical Research Council. From 2013 to 2015, Dominiczak was president of the European Society of Hypertension. She is the current Editor-in-Chief of Precision Medicine, a new journal launched in July 2023.
Simon James Gaskell is the previous president and principal of Queen Mary University of London, and current chair of the Quality Assurance Agency for Higher Education and chair of the board of governors of the University of Plymouth. He previously served as the vice-president for research at the University of Manchester.
Donald Robert James Singer was a British clinical pharmacologist who was the president of the Fellowship of Postgraduate Medicine.
Sir Nicholas Alcwyn Wright is a British professor and medical doctor. He was the Warden of Barts and The London School of Medicine and Dentistry.
Dame Parveen June Kumar is a British doctor who is Professor of Medicine and Education at Barts and The London School of Medicine and Dentistry. She worked in the NHS for over 40 years as a consultant gastroenterologist and physician at Barts and the London Hospitals and the Homerton University Hospital. She was the President of the British Medical Association in 2006, of the Royal Society of Medicine from 2010 to 2012, of the Medical Women's Federation from 2016 to 2018 and of the Royal Medical Benevolent Fund from 2013 to 2020. She was also Vice President of the Royal College of Physicians from 2003 to 2005. In addition, she was a founding non-executive director of the National Institute of Clinical Excellence, chaired the Medicines Commission UK until 2005, and also chaired the BUPA Foundation Charity for Research until 2013.
Elizabeth Matilda Tansey is an Emerita Professor of the history of medicine and former neurochemist, best known for her role in the Wellcome Trust's witness seminars. She previously worked at Queen Mary University of London (QMUL).
Genomics England is a British company set up and owned by the United Kingdom Department of Health and Social Care to run the 100,000 Genomes Project. The project aimed in 2014 to sequence 100,000 genomes from NHS patients with a rare disease and their families, and patients with cancer. An infectious disease strand is being led by Public Health England.
Professor Sir Munir Pirmohamed is a British clinical pharmacologist and geneticist. Since 2007 he has been the NHS Chair of Pharmacogenetics at the University of Liverpool.
The History of Modern Biomedicine Research Group (HoMBRG) is an academic organisation specialising in recording and publishing the oral history of twentieth and twenty-first century biomedicine. It was established in 1990 as the Wellcome Trust's History of Twentieth Century Medicine Group, and reconstituted in October 2010 as part of the School of History at Queen Mary University of London.
Sussan Nourshargh is a British immunologist, pharmacologist, and professor of microvascular pharmacology and immunopharmacology. She founded the Centre for Microvascular research at Queen Mary University.
Karim Hassan Brohi is a British surgeon who is currently the clinical director of the London Major Trauma Network, Professor of Trauma Sciences at Queen Mary University of London and a Consultant vascular and trauma surgeon for Barts Health NHS Trust at the Royal London Hospital.
Rupert Mark Pearse is a British physician specialising in intensive care medicine, and NIHR Professor of Intensive Care Medicine at Queen Mary University of London.
Paul Coulthard, BDS, MFGDP(UK), MDS, FDSRCS(Eng), FDSRCS(OS), PhD, FDSRCPS(Glas), FFDTRCS(Ed), FDSRCS(Ed), FCGDent is a British Academic, Surgeon and Scientist.
Amrita Ahluwalia is a British pharmacologist and professor of vascular pharmacology at Queen Mary University of London. Her research considers the development of therapeutics for cardiovascular inflammation. She was awarded the WISE Research Award in 2015.