Mary Lidstrom

Last updated
Mary E. Lidstrom
Born1951
Alma mater University of Wisconsin
Scientific career
Fields Microbiology
Institutions University of Washington
Thesis The regulation of C-1 metabolism in Methylobacterium organophilum  (1977)
Website depts.washington.edu/mllab/mLidstrom.php

Mary E. Lidstrom is a Professor of Microbiology at the University of Washington. She also holds the Frank Jungers Chair of Engineering, in the Department of Chemical Engineering. She currently is a fellow of the American Academy of Microbiology, a member of the National Academy of Sciences and serves on the editorial boards of the Journal of Bacteriology and FEMS Microbial Ecology. [1]

Contents

Education

Lidstrom received a B.S. degree in Microbiology from Oregon State University and an M.S. and PhD in Bacteriology from the University of Wisconsin-Madison. [2]

Research career

Lidstrom's work spans microbial physiology and natural complex microbial communities and has applications to biotechnology. Specifically, she has worked extensively on methylotroph bacteria that grow on one-carbon compounds. [3]

After conducting her doctorate research on C-1 metabolism in Methylobacterium organophilum, [4] Lidstrom undertook post-doctoral research at University of Sheffield UK with J. Rodney Quayle on species of the methylotrophic yeasts Hansenula and Candida, [5] :343 and then returned to the US with faculty posts at the University of Washington, University of Wisconsin-Milwaukee and the California Institute of Technology where she has taught courses on microbiology, oceanography, environmental engineering science, chemical engineering and bioengineering. While at Caltech she served as Vice-Chair of the Faculty. [6] In 1996 she moved to University of Washington and has remained there. [7]

Lidstrom is a fellow of the American Academy of Microbiology and a member of the National Academy of Sciences from 2013. [2] Lidstrom was the Vice Provost of Research at the University of Washington from 2005 until 2021. [8] [9] In addition, she served as Associate Dean for New Initiatives in Engineering from 1997 to 2005 and Interim Provost from 2010 to 2011. [10]

Publications

Lidstrom is the author or co-author of over 300 scientific publications. These include:

Honors

Related Research Articles

Methylotrophs are a diverse group of microorganisms that can use reduced one-carbon compounds, such as methanol or methane, as the carbon source for their growth; and multi-carbon compounds that contain no carbon-carbon bonds, such as dimethyl ether and dimethylamine. This group of microorganisms also includes those capable of assimilating reduced one-carbon compounds by way of carbon dioxide using the ribulose bisphosphate pathway. These organisms should not be confused with methanogens which on the contrary produce methane as a by-product from various one-carbon compounds such as carbon dioxide. Some methylotrophs can degrade the greenhouse gas methane, and in this case they are called methanotrophs. The abundance, purity, and low price of methanol compared to commonly used sugars make methylotrophs competent organisms for production of amino acids, vitamins, recombinant proteins, single-cell proteins, co-enzymes and cytochromes.

Persis S. Drell is the Provost Emerita and the James and Anna Marie Spilker Professor in the Stanford University School of Engineering, a professor of materials science and engineering, and a professor of physics. Prior to her appointment as provost, she was dean of the Stanford School of Engineering from 2014 to 2017 and director of the US Department of Energy’s SLAC National Acceleratory Laboratory from 2007 to 2012.

Methylorubrum extorquens is a Gram-negative bacterium. Methylorubrum species often appear pink, and are classified as pink-pigmented facultative methylotrophs, or PPFMs. The wild type has been known to use both methane and multiple carbon compounds as energy sources. Specifically, M. extorquens has been observed to use primarily methanol and C1 compounds as substrates in their energy cycles. It has been also observed that use lanthanides as a cofactor to increase its methanol dehydrogenase activity

Methylobacillus flagellatus is a species of aerobic bacteria.

<span class="mw-page-title-main">Methanol dehydrogenase</span>

In enzymology, a methanol dehydrogenase (MDH) is an enzyme that catalyzes the chemical reaction:

Angela K. Wilson is an American scientist and former (2022) President of the American Chemical Society. She currently serves as the John A. Hannah Distinguished Professor of Chemistry, associate dean for strategic initiatives in the College of Natural Sciences, and director of the MSU Center for Quantum Computing, Science, and Engineering (MSU-Q) at Michigan State University.

William E. Bentley is the Robert E. Fischell Distinguished Professor of Engineering, founding Director of the Fischell Institute for Biomedical Devices, and currently the Director of the Maryland Technology Enterprise Institute in the A. James Clark School of Engineering at the University of Maryland. He was previously the Chair of the Fischell Department of Bioengineering, where he assisted in establishing the department and provided leadership that led to its nationally ranked status.

<span class="mw-page-title-main">Jillian Banfield</span> Australian scientist

Jillian Fiona Banfield is professor at the University of California, Berkeley with appointments in the Earth Science, Ecosystem Science and Materials Science and Engineering departments. She is the director of microbiology the Innovative Genomics Institute, is affiliated with Lawrence Berkeley National Laboratory and has a position at the University of Melbourne, Australia. Some of her most noted work includes publications on the structure and functioning of microbial communities and the nature, properties and reactivity of nanomaterials.

Laura Lee Kiessling is an American chemist and the Novartis Professor of Chemistry at the Massachusetts Institute of Technology. Kiessling's research focuses on elucidating and exploiting interactions on the cell surface, especially those mediated by proteins binding to carbohydrates. Multivalent protein-carbohydrate interactions play roles in cell-cell recognition and signal transduction. Understanding and manipulating these interactions provides tools to study biological processes and design therapeutic treatments. Kiessling's interdisciplinary research combines organic synthesis, polymer chemistry, structural biology, and molecular and cell biology.

<span class="mw-page-title-main">JS Chiao</span>

Professor J. S. Chiao, born Jui-Sheng Jiao, was a microbiologist from the Shanghai Institute of Plant Physiology and Ecology of the Chinese Academy of Sciences, and a member of the American Society for Microbiology. Professor Chiao spent 60 years in microbiology research, and was one of the world's leading scientists on its application to the field of biotechnology.

<span class="mw-page-title-main">Julia Vorholt</span> Swiss microbiologist

Julia A. Vorholt is a full professor of microbiology at ETH Zurich and an elected member of the German Academy of Sciences Leopoldina.

Kartik Chandran is an American environmental engineer at Columbia University, where he is a professor in the Department of Earth and Environmental Engineering. He primarily works on the interface between environmental molecular and microbiology, environmental biotechnology and environmental engineering. The focus of his research is on elucidating the molecular microbial ecology and metabolic pathways of the microbial nitrogen cycle. Applications of his work have ranged from energy and resource efficient treatment of nitrogen containing wastewater streams, development and implementation of sustainable approaches to sanitation to novel models for resource recovery. Under his stewardship, the directions of biological wastewater treatment and biological nutrient removal were established for the first ever time in the history of Columbia University.

Methylobacterium organophilum is a facultatively methylotrophic bacteria from the genus of Methylobacterium which was isolated from sediments from the Lake Mendota in Madison in the United States. Methylobacterium organophilum can degrade methanol.

E. Virginia Armbrust is a biological oceanographer, professor, and current director of the University of Washington School of Oceanography. She is an elected member of the Washington State Academy of Science, an elected fellow of the American Association for the Advancement of Science, and an elected fellow of the American Academy of Microbiology.

Francis "Frank" J. Doyle III is an American engineer and academic administrator. He is the dean of the Harvard John A. Paulson School of Engineering and Applied Sciences and the John A. and Elizabeth S. Armstrong Professor of Engineering and Applied Sciences. Doyle is also affiliated with the Division of Sleep Medicine of Harvard Medical School. On December 15, 2022, it was announced that Doyle will serve as the 14th provost of Brown University starting in the 2023 academic year.

Greg N. Stephanopoulos is an American chemical engineer and the Willard Henry Dow Professor in the department of chemical engineering at the Massachusetts Institute of Technology. He has worked at MIT, Caltech, and the University of Minnesota in the areas of biotechnology, bioinformatics, and metabolic engineering especially in the areas of bioprocessing for biochemical and biofuel production. Stephanopoulos is the author of over 400 scientific publications with more than 35,000 citations as of April 2018. In addition, Greg has supervised more than 70 graduate students and 50 post-docs whose research has led to more than 50 patents. He was elected a fellow of the American Association for the Advancement of Science (2005), a member of the National Academy of Engineering (2003), and received the ENI Prize on Renewable Energy 2011.

Ann Patricia Wood is a retired British biochemist and bacteriologist who specialized in the ecology, taxonomy and physiology of sulfur-oxidizing chemolithoautotrophic bacteria and how methylotrophic bacteria play a role in the degradation of odour causing compounds in the human mouth, vagina and skin. The bacterial genus Annwoodia was named to honor her contributions to microbial research in 2017.

Jennifer B. Glass is a biogeochemist, geomicrobiologist, astrobiologist, and associate professor of biogeochemistry in the School of Earth and Atmospheric Sciences at the Georgia Institute of Technology in Atlanta, Georgia. Glass received the 2021 Thomas Hilker Award for Excellence in Biogeosciences from the American Geophysical Union. She was awarded the 2021 Alice C. Evans Award for Advancement of Women from the American Society of Microbiology.

Formatotrophs are organisms that can assimilate formate or formic acid to use as a carbon source or for reducing power. Some authors classify formatotrophs as one of the five trophic groups of methanogens, which also include hydrogenotrophs, acetotrophs, methylotrophs, and alcoholotrophs. Formatotrophs have garnered attention for applications in biotechnology as part of a "formate bioeconomy" in which synthesized formate could be used as a nutrient for microoganisms. Formate can be electrochemically synthesized from CO2 and renewable energy, and formatotrophs may be genetically modified to enhance production of biochemical products to be used as biofuels. Technical limitations in culturing formatotrophs have limited the discovery of natural formatotrophs and impeded research on their formate-metabolizing enzymes, which are of interest for applications in carbon sequestration and astrobiology.

Stuart L. Cooper is an American engineer. As a Full Professor and Chair of Ohio State University's Department of Chemical and Biomolecular Engineering, Cooper was elected to the National Academy of Engineering in 2011.

References

  1. 1 2 3 "Mary E. Lidstrom". UW Chemical Engineering. Retrieved 2022-03-02.
  2. 1 2 "Member Directory: Mary E. Lidstrom". National Academy of Sciences.
  3. Chistoserdova, Ludmila; Kalyuzhnaya, Marina G.; Lidstrom, Mary E. (2009). "The Expanding World of Methylotrophic Metabolism". Annual Review of Microbiology. 63: 477–499. doi:10.1146/annurev.micro.091208.073600. PMC   2827926 . PMID   19514844.
  4. O'Connor, Mary Lidstrom (1977). The regulation of C-1 metabolism in Methylobacterium organophilum. Madison, Wis.: University of Wisconsin. OCLC   609162422.
  5. Anthony, Christopher (2015). "JOHN RODNEY QUAYLE 18 November 1926 — 26 February 2006". Biogr. Mem. Fellows R. Soc. 61: 331–349. doi: 10.1098/rsbm.2015.0008 . S2CID   88245387.
  6. "Mary E. Lidstrom, Ph.D. CURRICULUM VITAE Education (formerly Mary L. O'Connor)". StudyLib. Retrieved 6 May 2022.
  7. "Mary E. Lidstrom, Ph.D. CURRICULUM VITAE Education (formerly Mary L. O'Connor)". StudyLib. Retrieved 6 May 2022.
  8. "Mary Lidstrom". University of Washington.
  9. Holtz, Jackson. "Mari Ostendorf named UW Vice Provost for Research". University of Washington. Retrieved 10 July 2021.
  10. "Mary E. Lidstrom, Ph.D. CURRICULUM VITAE Education (formerly Mary L. O'Connor)". StudyLib. Retrieved 6 May 2022.
  11. "Six AAAS Members Win American Society for Microbiology Award | American Association for the Advancement of Science". www.aaas.org. Retrieved 2022-03-02.
  12. "Mary E. Lidstrom". www.nasonline.org. Retrieved 2022-03-02.
  13. 1 2 "Awards and Recognition". UW ADVANCE. 2010-11-12. Retrieved 2022-03-02.
  14. "10 UW profs honored as Fellows of AAAS". UW News. Retrieved 2022-03-02.