McGowan Institute for Regenerative Medicine is a medical research institute which is a partnership between the University of Pittsburgh and the University of Pittsburgh Medical Center and is located in Pittsburgh, Pennsylvania, United States. It is directed by Professor Chandan K Sen.
In 1992, the McGowan Center for Artificial Organ Development was established through a gift from William G. McGowan, founder and chairman of MCI Communications. [1] McGowan experienced a heart attack in 1986, resulting in his receiving a heart transplant in 1987, at the University of Pittsburgh Medical Center. In 1990, William and Sue Gin McGowan donated $1 million to fund a center devoted to the studying artificial organ replacement. The McGowan Center for Artificial Organ Development was established in 1992. [2]
The McGowan Institute was formed in 2001 by consolidating the artificial organ and medical device research of the faculty affiliated with the McGowan Center with research related to tissue engineering and cell-based therapies. McGowan Institute works on tissue and organ insufficiency through tissue engineering, cell-based therapies, and medical devices and artificial organs, with an emphasis on translating the research findings of McGowan Institute affiliated faculty into clinical use.
The McGowan Institute works to address tissue and organ insufficiency through tissue engineering, cell-based therapies, and medical devices, and artificial organs, with an emphasis on translating the research findings of McGowan Institute affiliated faculty into clinical use. McGowan Institute is:
Biomedical engineering (BME) or medical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes. BME is also traditionally logical sciences to advance health care treatment, including diagnosis, monitoring, and therapy. Also included under the scope of a biomedical engineer is the management of current medical equipment in hospitals while adhering to relevant industry standards. This involves procurement, routine testing, preventive maintenance, and making equipment recommendations, a role also known as a Biomedical Equipment Technician (BMET) or as a clinical engineer.
An artificial organ is a human made organ device or tissue that is implanted or integrated into a human — interfacing with living tissue — to replace a natural organ, to duplicate or augment a specific function or functions so the patient may return to a normal life as soon as possible. The replaced function does not have to be related to life support, but it often is. For example, replacement bones and joints, such as those found in hip replacements, could also be considered artificial organs.
Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. Tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose, but is not limited to applications involving cells and tissue scaffolds. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance, it can is considered as a field of its own.
The University of Texas Southwestern Medical Center is a public academic health science center in Dallas, Texas. With approximately 23,000 employees, more than 3,000 full-time faculty, and nearly 4 million outpatient visits per year, UT Southwestern is the largest medical school in the University of Texas System and the State of Texas.
The Temerty Faculty of Medicine is the medical school of the University of Toronto. Founded in 1843, the faculty is based in Downtown Toronto and is one of Canada's oldest institutions of medical studies, being known for the discovery of insulin, stem cells and the site of the first single and double lung transplants in the world.
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.
The University of Pittsburgh School of Health and Rehabilitation Sciences is located in Pittsburgh, Pennsylvania.
Anthony Atala is an American bioengineer, urologist, and pediatric surgeon. He is the W.H. Boyce professor of urology, the founding director of the Wake Forest Institute for Regenerative Medicine, and the chair of the Department of Urology at Wake Forest School of Medicine in North Carolina. His work focuses on the science of regenerative medicine: "a practice that aims to refurbish diseased or damaged tissue using the body's own healthy cells".
The Wake Forest Institute for Regenerative Medicine (WFIRM) is a research institute affiliated with Wake Forest School of Medicine and located in Winston-Salem, North Carolina, United States
Doris Anita Taylor, Ph.D., FACC, FAHA is an American scientist working in regenerative medicine and tissue engineering. She was the Director, Regenerative Medicine Research and Director, Center for Cell and Organ Biotechnology at the Texas Heart Institute in Houston, Texas until March 2020. She is the Co-Founder of Miromatrix Medical, Inc. and Co-Founder of Organamet Bio, Inc.
The University of North Carolina School of Medicine is a professional school within the University of North Carolina at Chapel Hill. It offers a Doctor of Medicine degree along with combined Doctor of Medicine / Doctor of Philosophy or Doctor of Medicine / Master of Public Health degrees.
Sangeeta N. Bhatia is an American biological engineer and the John J. and Dorothy Wilson Professor at MIT’s Institute for Medical Engineering and Science and Electrical Engineering and Computer Science (EECS) at the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts, United States. Bhatia's research investigates applications of micro- and nano-technology for tissue repair and regeneration. She applies ideas from computer technology and engineering to the design of miniaturized biomedical tools for the study and treatment of diseases, in particular liver disease, hepatitis, malaria and cancer.
ThePartnership in Education is a non-profit multidisciplinary health literacy and informal science education project based at Duquesne University in Pittsburgh, Pennsylvania. The Partnership in Education produces planetarium shows and other multimedia that focus on topics in health and biology.
Donald E. Ingber is an American cell biologist and bioengineer. He is the founding director of the Wyss Institute for Biologically Inspired Engineering at Harvard University, the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children's Hospital, and Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences. He is also a member of the American Institute for Medical and Biological Engineering, the National Academy of Engineering, the National Academy of Medicine, the National Academy of Inventors, and the American Academy of Arts and Sciences.
MIRA is a multidisciplinary and complementary method for treating many chronic diseases. The MIRA Procedure is a result of combining efforts from different medical fields developed in the University of Chicago in 1992. It basically consists in medically grafting live rejuvenated tissue in the form of autologous adipose adult stem cells to a damaged organ in order to restore it and improve its function. This method is currently approved by the U.S. Food and Drug Administration (FDA).
Martin (Maish) L. Yarmush is an academic, American scientist, physician, and engineer known for his work in biotechnology and bioengineering. His faculty career began in 1984 at MIT as a Principal Research Associate in the Department of Chemical Engineering. In 1988 he joined Rutgers University, as Professor of Chemical and Biochemical Engineering. In 1995, he returned to the Boston area to serve as the Helen Andrus Benedict Professor of Surgery and Bioengineering in the Harvard-MIT Division of Health Sciences and Technology, and to establish the Center for Engineering in Medicine at the Harvard Affiliated Teaching Hospitals. In 2007 he returned to Rutgers to hold the Paul and Mary Monroe Endowed Chair in Science and Engineering and serve as Distinguished Professor in the Department of Biomedical Engineering. He also holds a Lecturer in Surgery and Bioengineering position at Harvard Medical School, and is a member of the Senior Scientific Staff at the Shriners Hospital for Children, Boston.
Thorsten Walles is a German general thoracic surgeon and professor at the University Hospital of Würzburg. He is known for his works in the field of trachea surgery and his research for early diagnosis of lung cancer.
The Institute for Bioengineering of Catalonia (IBEC) is an institution engaged in basic and applied research in bioengineering and nanomedicine, with experts working on tissue regeneration, biomechanics, molecular dynamics, biomimetics, drug delivery, organs ‘on-a-chip’, cell migration, stem cells, artificial olfaction and microbial biotechnology. The institute was created by the Government of Catalonia, the University of Barcelona and the Polytechnic University of Catalonia in December 2005 and is located at the Barcelona Science Park. The director of the institute is Prof. Josep Samitier, who took over from founding director Josep A. Planell i Estany in 2013. In 2014 IBEC was named a "Severo Ochoa Centre of Excellence" by the Spanish Ministry of Economy and Competitiveness.
Rocky Tuan Sung-chi is a Hong Kong medical researcher and bioengineer, currently the vice-chancellor and president of the Chinese University of Hong Kong, where he served as distinguished visiting professor and director of the Institute for Tissue Engineering and Regenerative Medicine prior to taking up the vice-chancellorship. Previously he was on the faculty at the University of Pittsburgh, where he held a number of roles: Arthur J. Rooney Sr. Professor of Sports Medicine and the executive vice chair of the department of Orthopaedic Surgery, and a professor in the department of bioengineering. He was the director of the Center for Military Medicine Research and an associate director of the McGowan Institute for Regenerative Medicine. Despite his position in Hong Kong, he continues to serve as the director of the University of Pittsburgh's Center for Cellular and Molecular Engineering. For the 2018 fiscal year, he was one of the top 25 highest-paid University of Pittsburgh employees.
Chandan K. Sen is an Indian-American scientist who is known for contributions to the fields of regenerative medicine and wound care. He is currently the Director of the McGowan Institute for Regenerative Medicine of the University of Pittsburgh. He is an University Endowed Professor of Surgery who also serves as the Chief Scientific Officer of wound care services of the University of Pittsburgh Medical Center health system. At the University of Pittsburgh, Professor Sen serves as Associate Vice Chancellor for Life Sciences Innovation and Commercialization.
Attribution:
This article incorporates material from the McGowan Institute for Regenerative Medicine web page entitled About Us..