Measles & Rubella Initiative (MRI), launched in 2001, is a long-term commitment and partnership among leaders in public health and supports the goal of reducing measles deaths globally by 90% by 2010 compared to 2000 estimates.
Largely due to the technical and financial support of the Measles Initiative and the commitment from African governments, 217 million children have been vaccinated against measles and 1.2 million lives have been saved since 1999. Building on this achievement, in 2005, the Initiative has expanded its technical and financial support to countries in Asia, where total measles deaths are highest outside of sub-Saharan Africa. [1] Since 2001, the Measles Initiative has mobilized more than $200 million and supported more than 40 African countries and three Asian countries in implementing high-quality measles vaccination campaigns. As a result, global measles deaths have dropped by 48% from 871,000 in 1999 to an estimated 454,000 in 2004 thanks to improvements in routine and supplementary immunization activities. The largest reduction occurred in Africa, the region with the highest burden of the disease, where estimated measles cases and deaths dropped by 60%. [2]
The mechanism for the Initiative is an American Red Cross-led partnership with operational support to measles burdened countries. The Initiative has adopted the highly successful Rotary-led global polio eradication initiative as a model. [2] Rotary's strategy was two-fold: repeated vaccination campaigns reinforced by routine vaccination. The Initiative employs a similar approach - initial mass catch-up campaigns to vaccinate every child who may be at risk with follow-up campaigns three to four years later to vaccinate children who have been born since the catch-up campaign.[ citation needed ]
In February 2001, American Red Cross convened a meeting with other global healthcare organizations. American Red Cross, CDC, UNICEF, UN Foundation, and WHO met to discuss the growing problem of measles in Africa. The organizations decided that the problem needed immediate action, especially considering that death from measles is preventable. [3] In the battle to reduce mortality from measles, partnership is crucial because each player brings a different strength and talent to bear. WHO designs the policies and health guidelines for each country to ensure proper, safe steps are taken during immunization campaigns. UNICEF is the only organization allowed to import the vaccine into most developing countries and has a sophisticated logistics capacity as well as great stature in the country. CDC provides funding and the technical and scientific basis for the policies and advises countries on program planning. The UN Foundation provides a substantial amount of funding as well as the financial mechanisms necessary to move funds between agencies and to countries. [4] American Red Cross provides funding and has the network of Red Cross societies around the world and the volunteers to do social mobilization, ensuring each child has a chance to be vaccinated.[ citation needed ]
The partners of Measles Initiative are:[ citation needed ]
These organization endorsed a joint declaration on January 31, 2001 declaring their intent to fight measles in Africa.
Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them. The effectiveness of vaccination has been widely studied and verified. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio and tetanus from much of the world. However, some diseases, such as measles outbreaks in America, have seen rising cases due to relatively low vaccination rates in the 2010s – attributed, in part, to vaccine hesitancy.
The United Nations Foundation is a charitable organization headquartered in Washington, DC, that supports the United Nations and its activities. It was established in 1998 with a $1 billion gift to the United Nations by philanthropist Ted Turner, who believed the UN was crucial for addressing the world's problems. Originally primarily a grantmaker, the UN Foundation has evolved into a strategic partner to the UN, mobilizing support to advance the Sustainable Development Goals (SDGs), and help the UN address issues such as climate change, global health, gender equality, human rights, data and technology, peace, and humanitarian responses. The UN Foundation's main work occurs through building public-private partnerships, communities, initiatives, campaigns, and alliances to broaden support for the UN and solve global problems. The UN Foundation has helped build awareness and advocate for action on, among others, antimicrobial resistance, regional action on climate change, local implementation of the SDGs, as well as global campaigns such as Nothing But Nets against malaria, the Measles & Rubella Initiative, the Clean Cooking Alliance, Girl Up, Shot@Life, and the Digital Impact Alliance, among others. In March 2020, the UN Foundation was also a key founder of the COVID-19 Solidarity Response Fund on behalf of the World Health Organization (WHO), helping to raise over $200 million USD within the first six weeks to support the global response to the COVID-19 pandemic.
Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than 40 °C (104 °F), cough, runny nose, and inflamed eyes. Small white spots known as Koplik's spots may form inside the mouth two or three days after the start of symptoms. A red, flat rash which usually starts on the face and then spreads to the rest of the body typically begins three to five days after the start of symptoms. Common complications include diarrhea, middle ear infection (7%), and pneumonia (6%). These occur in part due to measles-induced immunosuppression. Less commonly seizures, blindness, or inflammation of the brain may occur. Other names include morbilli, rubeola, red measles, and English measles. Both rubella, also known as German measles, and roseola are different diseases caused by unrelated viruses.
Pulse Polio is an immunisation campaign established by the government of India to eliminate poliomyelitis (polio) in India by vaccinating all children under the age of five years against the polio virus. The project fights polio through a large-scale, pulse vaccination programme and monitoring for poliomyelitis cases.
A vaccination policy is a health policy adopted in order to prevent the spread of infectious disease. These policies are generally put into place by State or local governments, but may also be set by private facilities, such as workplaces or schools. Many policies have been developed and implemented since vaccines were first made widely available.
Eradication is the reduction of an infectious disease's prevalence in the global host population to zero.
The Expanded Program on Immunization is a World Health Organization program with the goal to make vaccines available to all children.
Measles vaccine protects against becoming infected with measles. Nearly all of those who do not develop immunity after a single dose develop it after a second dose. When rate of vaccination within a population is greater than 92%, outbreaks of measles typically no longer occur; however, they may occur again if the rate of vaccination decrease. The vaccine's effectiveness lasts many years. It is unclear if it becomes less effective over time. The vaccine may also protect against measles if given within a couple of days after exposure to measles.
Yellow fever vaccine is a vaccine that protects against yellow fever. Yellow fever is a viral infection that occurs in Africa and South America. Most people begin to develop immunity within ten days of vaccination and 99 percent are protected within one month, and this appears to be lifelong. The vaccine can be used to control outbreaks of disease. It is given either by injection into a muscle or just under the skin.
Health in Angola is rated among the worst in the world.
European Immunization Week (EIW) is an annual regional initiative, coordinated by the World Health Organization Regional Office for Europe (WHO/Europe), to promote immunization against vaccine-preventable diseases since its launch in 2008. EIW activities are carried out by participating WHO/Europe member states. In the past these have included: disseminating informational materials about immunization, organizing immunization campaigns, organizing training sessions for health care workers, arranging workshops or conferences with political decision makers to discuss immunization, and holding press conferences about immunization-related issues.
Pakistan is one of the two remaining countries in the world where poliomyelitis (polio) is still categorized as an endemic viral infection, the other one being Afghanistan. As of August 2022, there has been 14 documented cases in Pakistan in 2022. There was 1 documented case in Pakistan in 2021 and 84 documented cases in Pakistan in 2020. The total count of wild poliovirus cases in Pakistan in 2019 was 147.
GAVI, officially Gavi, the Vaccine Alliance is a public–private global health partnership with the goal of increasing access to immunization in poor countries. In 2016, Gavi channeled more than half of total donor assistance for health, and most donor assistance for immunization, by monetary measure.
Measles is extremely contagious, but surviving the infection results in lifelong immunity, so its continued circulation in a community depends on the generation of susceptible hosts by birth of children. In communities which generate insufficient new hosts the disease will die out. This concept was first recognized by Bartlett in 1957, who referred to the minimum number supporting measles as the critical community size (CCS). Analysis of outbreaks in island communities suggested that the CCS for measles is c. 250,000.
India National PolioPlus Society is a non-profit organization. The Initiative has achieved significant progress toward its goals. There has been a dramatic decline in cases everywhere in the seventeen years since the target was set in 1988.
The Global Polio Eradication Initiative is an initiative created in 1988, just after the World Health Assembly resolved to eradicate the disease poliomyelitis. Led by the World Health Organization, it is the largest international public health initiative in history.
Dr. Robert Kezaala is a medical doctor, epidemiologist, scholar and public health leader in the field of immunization and health emergencies. Currently he is serving as a Senior Health Advisor and team lead for Accelerated Immunization Initiatives: measles, rubella, epidemic meningitis and yellow fever control and Immunization in Emergencies at the United Nations Children’s Fund.
The 2019 Philippines measles outbreak began in early 2019. An outbreak of measles was officially declared in February 2019 in select administrative regions in Luzon and Visayas including Metro Manila by the Philippine government. The outbreak is attributed to lowered vaccination rates, from a high of 88% 10 to 15 years previous to 74% at the time of the outbreak, allegedly caused by the Dengvaxia controversy.
The 2019 Samoa measles outbreak began in September 2019. As of 6 January 2020, there were over 5,700 cases of measles and 83 deaths, out of a Samoan population of 200,874. Over three percent of the population were infected. The cause of the outbreak was attributed to decreased vaccination rates, from 74% in 2017 to 31–34% in 2018, even though nearby islands had rates near 99%.
The 2022 edition of the World Immunization Week will be observed from 24 to 30 April, 2022. The World Immunization Week is a global public health campaign for raising awareness for immunization against vaccine preventable diseases. The theme of this year's event is Long Life for All-in pursuit of a long life well lived. The official hashtags of the event are #Vaccines4Life and #LongLifeForAll. The organizations such as UNICEF, GAVI and Global Polio Eradication Initiative have partnered with the World Health Organization in the 2022 edition of World Immunization Week.