Measles & Rubella Initiative

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Measles & Rubella Initiative (MRI), launched in 2001, is a long-term commitment and partnership among leaders in public health and supports the goal of reducing measles deaths globally by 90% by 2010 compared to 2000 estimates.

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Impact

Largely due to the technical and financial support of the Measles Initiative and the commitment from African governments, 217 million children have been vaccinated against measles and 1.2 million lives have been saved since 1999. Building on this achievement, in 2005, the Initiative has expanded its technical and financial support to countries in Asia, where total measles deaths are highest outside of sub-Saharan Africa. [1] Since 2001, the Measles Initiative has mobilized more than $200 million and supported more than 40 African countries and three Asian countries in implementing high-quality measles vaccination campaigns. As a result, global measles deaths have dropped by 48% from 871,000 in 1999 to an estimated 454,000 in 2004 thanks to improvements in routine and supplementary immunization activities. The largest reduction occurred in Africa, the region with the highest burden of the disease, where estimated measles cases and deaths dropped by 60%. [2]

Structure

The mechanism for the Initiative is an American Red Cross-led partnership with operational support to measles burdened countries. The Initiative has adopted the highly successful Rotary-led global polio eradication initiative as a model. [2] Rotary's strategy was two-fold: repeated vaccination campaigns reinforced by routine vaccination. The Initiative employs a similar approach - initial mass catch-up campaigns to vaccinate every child who may be at risk with follow-up campaigns three to four years later to vaccinate children who have been born since the catch-up campaign.[ citation needed ]

Background

In February 2001, American Red Cross convened a meeting with other global healthcare organizations. American Red Cross, CDC, UNICEF, UN Foundation, and WHO met to discuss the growing problem of measles in Africa. The organizations decided that the problem needed immediate action, especially considering that death from measles is preventable. [3] In the battle to reduce mortality from measles, partnership is crucial because each player brings a different strength and talent to bear. WHO designs the policies and health guidelines for each country to ensure proper, safe steps are taken during immunization campaigns. UNICEF is the only organization allowed to import the vaccine into most developing countries and has a sophisticated logistics capacity as well as great stature in the country. CDC provides funding and the technical and scientific basis for the policies and advises countries on program planning. The UN Foundation provides a substantial amount of funding as well as the financial mechanisms necessary to move funds between agencies and to countries. [4] American Red Cross provides funding and has the network of Red Cross societies around the world and the volunteers to do social mobilization, ensuring each child has a chance to be vaccinated.[ citation needed ]

Partners

The partners of Measles Initiative are:[ citation needed ]

These organization endorsed a joint declaration on January 31, 2001 declaring their intent to fight measles in Africa.

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Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them. The effectiveness of vaccination has been widely studied and verified. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio and tetanus from much of the world. However, some diseases, such as measles outbreaks in America, have seen rising cases due to relatively low vaccination rates in the 2010s – attributed, in part, to vaccine hesitancy.

United Nations Foundation

The United Nations Foundation is a charitable organization headquartered in Washington, DC, that supports the United Nations and its activities. It was established in 1998 with a $1 billion gift to the United Nations by philanthropist Ted Turner, who believed the UN was crucial for addressing the world's problems. Originally primarily a grantmaker, the UN Foundation has evolved into a strategic partner to the UN, mobilizing support to advance the Sustainable Development Goals (SDGs), and help the UN address issues such as climate change, global health, gender equality, human rights, data and technology, peace, and humanitarian responses. The UN Foundation's main work occurs through building public-private partnerships, communities, initiatives, campaigns, and alliances to broaden support for the UN and solve global problems. The UN Foundation has helped build awareness and advocate for action on, among others, antimicrobial resistance, regional action on climate change, local implementation of the SDGs, as well as global campaigns such as Nothing But Nets against malaria, the Measles & Rubella Initiative, the Clean Cooking Alliance, Girl Up, Shot@Life, and the Digital Impact Alliance, among others. In March 2020, the UN Foundation was also a key founder of the COVID-19 Solidarity Response Fund on behalf of the World Health Organization (WHO), helping to raise over $200 million USD within the first six weeks to support the global response to the COVID-19 pandemic.

Measles Viral disease affecting humans

Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than 40 °C (104 °F), cough, runny nose, and inflamed eyes. Small white spots known as Koplik's spots may form inside the mouth two or three days after the start of symptoms. A red, flat rash which usually starts on the face and then spreads to the rest of the body typically begins three to five days after the start of symptoms. Common complications include diarrhea, middle ear infection (7%), and pneumonia (6%). These occur in part due to measles-induced immunosuppression. Less commonly seizures, blindness, or inflammation of the brain may occur. Other names include morbilli, rubeola, red measles, and English measles. Both rubella, also known as German measles, and roseola are different diseases caused by unrelated viruses.

Pulse Polio

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Eradication of infectious diseases Complete extermination of disease causing agent effectively to reduce its incidence to zero

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GAVI Global health organization

GAVI, officially Gavi, the Vaccine Alliance is a public–private global health partnership with the goal of increasing access to immunization in poor countries. In 2016, Gavi channeled more than half of total donor assistance for health, and most donor assistance for immunization, by monetary measure.

<span class="mw-page-title-main">Epidemiology of measles</span>

Measles is extremely contagious, but surviving the infection results in lifelong immunity, so its continued circulation in a community depends on the generation of susceptible hosts by birth of children. In communities which generate insufficient new hosts the disease will die out. This concept was first recognized by Bartlett in 1957, who referred to the minimum number supporting measles as the critical community size (CCS). Analysis of outbreaks in island communities suggested that the CCS for measles is c. 250,000.

India National PolioPlus Society is a non-profit organization. The Initiative has achieved significant progress toward its goals. There has been a dramatic decline in cases everywhere in the seventeen years since the target was set in 1988.

Global Polio Eradication Initiative Initiative to eradicate polio

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