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Forgetting or disremembering is the apparent loss or modification of information already encoded and stored in an individual's short or long-term memory. It is a spontaneous or gradual process in which old memories are unable to be recalled from memory storage. Problems with remembering, learning and retaining new information are a few of the most common complaints of older adults. Studies show that retention improves with increased rehearsal. This improvement occurs because rehearsal helps to transfer information into long-term memory.
The forgetting curve hypothesizes the decline of memory retention in time. This curve shows how information is lost over time when there is no attempt to retain it. A related concept is the strength of memory that refers to the durability that memory traces in the brain. The stronger the memory, the longer period of time that a person is able to recall it. A typical graph of the forgetting curve purports to show that humans tend to halve their memory of newly learned knowledge in a matter of days or weeks unless they consciously review the learned material.
The flatworms, flat worms, Platyhelminthes, or platyhelminths are a phylum of relatively simple bilaterian, unsegmented, soft-bodied invertebrates. Being acoelomates, and having no specialised circulatory and respiratory organs, they are restricted to having flattened shapes that allow oxygen and nutrients to pass through their bodies by diffusion. The digestive cavity has only one opening for both ingestion and egestion ; as a result, the food cannot be processed continuously.
Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, imagination, intelligence, the formation of knowledge, memory and working memory, judgment and evaluation, reasoning and computation, problem-solving and decision-making, comprehension and production of language. Cognitive processes use existing knowledge and discover new knowledge.
Planarians (triclads) are free-living flatworms of the class Turbellaria, order Tricladida, which includes hundreds of species, found in freshwater, marine, and terrestrial habitats. Planarians are characterized by a three-branched intestine, including a single anterior and two posterior branches. Their body is populated by adult stem cells called neoblasts, which planarians use for regenerating missing body parts. Many species are able to regenerate any missing organ, which has made planarians a popular model in research of regeneration and stem cell biology. The genome sequences of several species are available, as are tools for molecular biology analysis.
Motor learning refers broadly to changes in an organism's movements that reflect changes in the structure and function of the nervous system. Motor learning occurs over varying timescales and degrees of complexity: humans learn to walk or talk over the course of years, but continue to adjust to changes in height, weight, strength etc. over their lifetimes. Motor learning enables animals to gain new skills, and improves the smoothness and accuracy of movements, in some cases by calibrating simple movements like reflexes. Motor learning research often considers variables that contribute to motor program formation, sensitivity of error-detection processes, and strength of movement schemas. Motor learning is "relatively permanent", as the capability to respond appropriately is acquired and retained. Temporary gains in performance during practice or in response to some perturbation are often termed motor adaptation, a transient form of learning. Neuroscience research on motor learning is concerned with which parts of the brain and spinal cord represent movements and motor programs and how the nervous system processes feedback to change the connectivity and synaptic strengths. At the behavioral level, research focuses on the design and effect of the main components driving motor learning, i.e. the structure of practice and the feedback. The timing and organization of practice can influence information retention, e.g. how tasks can be subdivided and practiced, and the precise form of feedback can influence preparation, anticipation, and guidance of movement.
Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system and the peripheral nervous system that do not produce electrical impulses. The neuroglia make up more than one half the volume of neural tissue in our body. They maintain homeostasis, form myelin in the peripheral nervous system, and provide support and protection for neurons. In the central nervous system, glial cells include oligodendrocytes, astrocytes, ependymal cells and microglia, and in the peripheral nervous system they include Schwann cells and satellite cells.
An engram is a unit of cognitive information imprinted in a physical substance, theorized to be the means by which memories are stored as biophysical or biochemical changes in the brain or other biological tissue, in response to external stimuli.
Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete after which the necrotic tissue becomes fibrotic.
Planaria is a genus of planarians in the family Planariidae. Due to its excellent ability to regenerate, species of Planaria has also been used as model organisms in regeneration studies. When an individual is cut into pieces, each piece has the ability to regenerate into a fully formed individual. When decapitated, they retain their memories.
James V. McConnell was an American biologist and animal psychologist. He is most known for his research on learning and memory transfer in planarians conducted in the 1950s and 1960s. McConnell also published several science fiction short stories in the mid-1950s.
The Papez circuit, or medial limbic circuit, is a neural circuit for the control of emotional expression. In 1937, James Papez proposed that the circuit connecting the hypothalamus to the limbic lobe was the basis for emotional experiences. Paul D. MacLean reconceptualized Papez's proposal and coined the term limbic system. MacLean redefined the circuit as the "visceral brain" which consisted of the limbic lobe and its major connections in the forebrain – hypothalamus, amygdala, and septum. Over time, the concept of a forebrain circuit for the control of emotional expression has been modified to include the prefrontal cortex.
Body memory (BM) is a hypothesis that the body itself is capable of storing memories, as opposed to only the brain. While experiments have demonstrated the possibility of cellular memory there are currently no known means by which tissues other than the brain would be capable of storing memories.
The Worm Runner's Digest (W.R.D.) was created in 1959 by biologist James V. McConnell after his experiments with memory transfer in planarian worms generated a torrent of mail enquiries. The W.R.D. published both satirical articles, such as "A Stress Analysis of a Strapless Evening Gown", and scientific papers, the most famous of which, "Memory transfer through cannibalism in planarians", was a result of McConnell's RNA memory transfer experiments with planarian worms and was later published in the Journal of Neuropsychiatry.
Activity-dependent plasticity is a form of functional and structural neuroplasticity that arises from the use of cognitive functions and personal experience; hence, it is the biological basis for learning and the formation of new memories. Activity-dependent plasticity is a form of neuroplasticity that arises from intrinsic or endogenous activity, as opposed to forms of neuroplasticity that arise from extrinsic or exogenous factors, such as electrical brain stimulation- or drug-induced neuroplasticity. The brain's ability to remodel itself forms the basis of the brain's capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is associated with neural plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity occurs as a result of changes in gene expression which are triggered by signaling cascades that are activated by various signaling molecules during increased neuronal activity.
Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition. A memory trace is a change in the nervous system caused by memorizing something. Consolidation is distinguished into two specific processes. The first, synaptic consolidation, which is thought to correspond to late-phase long-term potentiation, occurs on a small scale in the synaptic connections and neural circuits within the first few hours after learning. The second process is systems consolidation, occurring on a much larger scale in the brain, rendering hippocampus-dependent memories independent of the hippocampus over a period of weeks to years. Recently, a third process has become the focus of research, reconsolidation, in which previously consolidated memories can be made labile again through reactivation of the memory trace.
In philosophy of mind, qualia are defined as instances of subjective, conscious experience. The term qualia derives from the Latin neuter plural form (qualia) of the Latin adjective quālis meaning "of what sort" or "of what kind" in relation to a specific instance, such as "what it is like to taste a specific apple — this particular apple now".
Girardia dorotocephala is a species of dugesiid triclad native to North America. It has been accidentally introduced in Japan. Girardia dorotocephala is cannibalistic, which led to its usage in memory transfer experiments.
In philosophy of mind, the extended mind thesis says that the mind does not exclusively reside in the brain or even the body, but extends into the physical world. The thesis proposes that some objects in the external environment can be part of a cognitive process and in that way function as extensions of the mind itself. Examples of such objects are written calculations, a diary, or a PC; in general, it concerns objects that store information. The hypothesis considers the mind to encompass every level of cognition, including the physical level.
Neoblasts (ˈniːəʊˌblæst) are adult stem cells found in planarian flatworms. They are the only dividing planarian cells, and they produce all cell types, including the germline. Neoblasts are abundant in the planarian parenchyma, and comprise up to 30 percent of all cells. Following injury, neoblasts rapidly divide and generate new cells, which allows planarians to regenerate any missing tissue.
References
- 1 2 Tan, Loh Teng-Hern; Ser, Hooi-Leng; Ong, Yong Sze; Khaw, Kooi Yeong; Pusparajah, Priyia; Chan, Kok-Gan; Lee, Learn-Han; Goh, Bey-Hing (2020). "Reckoning the Unresolved Scientific Question on Memory Transfer". Progress in Drug Discovery & Biomedical Science. 3. doi: 10.36877/pddbs.a0000105 .
- 1 2 Bob Kentridge. "Investigations of the cellular bases of memory". University of Durham. Archived from the original on 2012-10-15. Retrieved 2011-03-03.
- ↑ McFarling,STAT, Usha Lee. "Memory Transferred between Snails, Challenging Standard Theory of How the Brain Remembers". Scientific American. Retrieved 2019-03-10.
- ↑ Dave, Shivani (2018-05-14). "'Memory transplant' achieved in snails" . Retrieved 2019-03-10.
- 1 2 3 4 5 "The memory-transfer episode". www.apa.org. Retrieved 2021-02-05.
- 1 2 William L. Mikulas. "Physiology of Learning". University of West Florida. Archived from the original on 2017-11-27. Retrieved 2011-03-03.
- ↑ James, McConnell (1965). "A Manual of Psychological Experimentation on Planarians" (PDF). The Worm Runner's Digest : 5, 7 – via https://www.tufts.edu/.
{{cite journal}}: External link in|via= - ↑ Duhaime-Ross, Arielle (17 September 2013). "Flatworms Recall Familiar Environs, Even after Losing Their Heads". Scientific American . Retrieved 18 March 2015.
- ↑ Shomrat T, Levin M (2013-07-02). "An automated training paradigm reveals long-term memory in planaria and its persistence through head regeneration". The Journal of Experimental Biology. 216 (20): 3799–3810. doi: 10.1242/jeb.087809 . PMID 23821717.
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