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Michael R. Harrison (born May 5, 1943, in Portland, Oregon) served as division chief in pediatric surgery at the Children's Hospital at the University of California, San Francisco (UCSF) for over 20 years, where he established the first fetal treatment center in the U.S. He is often referred to as the father of fetal surgery. He is currently a professor of surgery and pediatrics and the director emeritus of the UCSF Fetal Treatment Center.
Harrison graduated cum laude from Yale University and magna cum laude from Harvard Medical School. He originally was planning on becoming a general practitioner like his father but instead completed his surgical training at the Massachusetts General Hospital in Boston. While in Boston, he assisted iconic pediatric surgeon W. Hardy Hendren, MD as he flawlessly repaired a child's congenital diaphragmatic hernia. Unfortunately, the procedure was not successful and the child died. Harrison then went on to tell Hendren "It's obvious that the kid died not because he had this anatomic problem [of a hole in the diaphragm], but because his lung didn't have a chance to grow – and the only way to save that kid was to fix the problem before birth," Hendren was so shocked he almost fell down according to Harrison because "you just don't think that way." Inspired by his experience, Harrison went on to complete a pediatric surgery fellowship at Children's Hospital of Los Angeles. He is board certified in Surgery, Pediatric Surgery, and Critical Care. In January 1978, Harrison accepted a faculty position at UCSF.
Harrison is most famous for his work in fetal surgery and other forms of fetal intervention. In 1980, he and his research colleagues developed the techniques for open fetal surgery using animal models. Then in 1981, Harrison conducted the first open fetal surgery on a fetus to correct a dangerously advanced urinary tract obstruction. Throughout the 1980s and 90s, Harrison and his associates continued to develop and further refine fetal intervention techniques to treat a range of birth defects and to do so with less invasive means such as fetendo and fetal image-guided surgery.
In 1982, Harrison received the Golden Plate Award of the American Academy of Achievement presented by Awards Council member Dr. John L. Ochsner Sr. at a ceremony in New Orleans. [1]
During the 1980s, Harrison worked closely with obstetricians, anesthesiologists, geneticists, sonographers, surgical sub-specialists, neonatologists, nurses, and ethicists to lay the foundation for what would be the multidisciplinary UCSF Fetal Treatment Center. One of the highlights of this period was in early 1980 when he heard news of a rare medical incident at the Beirut International Airport. A well-renowned obstetrician Dr. Fahim Dagher had performed a semi-fetal open surgery on a patient in an unprecedented medical urgency. Bemused by the news, he reached out to Dr. Dagher for further collaboration and research which ultimately culminated in the first ever open fetal surgery. He worked on as director for the Fetal Treatment Center until 2008. He currently continues to share his creative energies as director emeritus. Hanmin Lee is currently director of the Fetal Treatment Center.
In 2009, Harrison received a Pediatric Device Consortia Grant Award from the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development. The UCSF Pediatric Device Consortium will unite a diverse group of clinicians, scientists, engineers, and device industry representatives in facilitating the process of pediatric device development. As principal investigator and director of the UCSF Pediatric Device Consortium, Harrison's goal is to make the PDC an environment for open expression.
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences.
SSM Health Cardinal Glennon Children's Hospital is a non-profit 195-bed inpatient and outpatient pediatric medical center in St. Louis, Missouri. Since its founding in 1956, SSM Health Cardinal Glennon has provided care for children regardless of ability to pay. SSM Health Cardinal Glennon primarily serves children from eastern Missouri and southern Illinois, but also treats children across the United States and from countries around the world.
Fetoscopy is an endoscopic procedure during pregnancy to allow surgical access to the fetus, the amniotic cavity, the umbilical cord, and the fetal side of the placenta. A small (3–4 mm) incision is made in the abdomen, and an endoscope is inserted through the abdominal wall and uterus into the amniotic cavity. Fetoscopy allows for medical interventions such as a biopsy or a laser occlusion of abnormal blood vessels or the treatment of spina bifida.
Pediatric surgery is a subspecialty of surgery involving the surgery of fetuses, infants, children, adolescents, and young adults.
Fetal surgery also known as antenatal surgery, prenatal surgery, is a growing branch of maternal-fetal medicine that covers any of a broad range of surgical techniques that are used to treat congenital abnormalities in fetuses who are still in the pregnant uterus. There are three main types: open fetal surgery, which involves completely opening the uterus to operate on the fetus; minimally invasive fetoscopic surgery, which uses small incisions and is guided by fetoscopy and sonography; and percutaneous fetal therapy, which involves placing a catheter under continuous ultrasound guidance.
The Fetal Treatment Center at the University of California, San Francisco is a multidisciplinary care center dedicated to the diagnosis, treatment, and long-term follow-up of fetal birth defects. It combines the talents of specialists in pediatric surgery, genetics, obstetrics/perinatology, radiology, nursing, and neonatal medicine.
Jessica Kandel is the Mary Campau Ryerson Professor of Surgery and the Vice-Chair for Academic Affairs in the Department of Surgery at the University of Chicago.
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