Michael Stifelman

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Michael Stifelman, M.D.

Michael D. Stifelman (born May 7, 1967) is an American urologist. He is known for his introducing surgical techniques in urology, including developments in robotic partial nephrectomy, the use of near-infrared fluorescence imaging in renal surgery. [1]

Contents

He is a Chair of Urology at Hackensack University Medical Center, Director of Robotic Surgery at Hackensack Meridian Health, and Professor and Inaugural Chair of Urology at Hackensack Meridian School of Medicine. [2]

Biography

Stifelman earned his undergraduate degree in zoology from the University of Massachusetts and his medical degree from the Albert Einstein College of Medicine in the Bronx, NY. [3]

Stifelman joined HackensackUMC in 2016 after working at NYU Langone Medical Center, where he was Professor of Urology at the NYU School of Medicine, [4] Director of the Robotic Surgery Center, and Chief of Urology Services at Tisch Hospital. [5]

He completed his internship and residency in general surgery, as well as his urology residency at Columbia Presbyterian Medical Center, NY, serving as chief resident in urology during his final year. [3] He received his fellowship in endourology and laparoscopy at Weill Cornell Medical Center, New York, NY, and is board certified in urology. [2]

Stifelman currently serves as Professor and Inaugural Chair of Urology, Hackensack Meridian School of Medicine; Chair of Urology, Hackensack Meridian Hackensack University Medical Center; Director of Urologic Oncology at John Theurer Cancer Center; and Director of Robotic Surgery, Hackensack Meridian Health.

From 2009 to 2012, he was a co-investigator in a Vivus-sponsored study on Avanafil for erectile dysfunction after prostatectomy, and in the NIH/Gen-Probe-sponsored EDRN PCA3 Validation Trial. [6] In 2015, he was a co-investigator in the ADAPT Phase 3 trial on dendritic cell immunotherapy for advanced renal cell carcinoma. [7] Since 2016, he has been the principal investigator in the TARPAN Study on the use of the AirSeal system in robotic partial nephrectomy. [8] He is also the principal investigator of a study on prostasomes as a diagnostic tool for prostate cancer, ongoing since 2018. [9]

Stifelman’s current translational research interests include prostasomes for prostate cancer detection, creating a biorepository of urologic cancers, and amniotic membrane nerve regeneration.

Research

CLARIX Clinical Trial

Stifelman serves as the principal investigator of a prospective, randomized controlled clinical trial at Hackensack University Medical Center evaluating the efficacy of CLARIX® CORD 1K, a cryopreserved umbilical cord allograft, in enhancing functional recovery following bilateral nerve-sparing robot-assisted radical prostatectomy (RARP). [10] The trial, titled Prospective, Controlled Study Evaluating Recovery of Potency and Continence Following Robot-Assisted Radical Prostatectomy with and without Cryopreserved Umbilical Cord Allograft, enrolls 100 male participants randomized in a 1:1 ratio to undergo either standard RARP or RARP with intraoperative CLARIX application. [11]

The trial builds upon retrospective findings presented by Stifelman's colleague Ravi Munver at the 2018 World Congress of Endourology, which suggested that CLARIX may support earlier functional recovery post-surgery. [10]

Herpes Simplex Virus (HSV) Gene Therapy Research

In addition to his work in robotic surgery, Stifelman collaborates on translational research involving the use of herpes simplex virus (HSV) as a vector for gene therapy. This line of investigation focuses on developing targeted drug delivery systems to treat chronic urologic conditions, such as neurogenic detrusor overactivity and other lower urinary tract dysfunctions. [12]

Honors and awards

Selected works and publications

References

  1. "Dr. Stifelman discusses 3D modeling tool for robotic-assisted surgery". Urology Times. 9 July 2024.
  2. 1 2 McCoy, Amanda (2024-09-26). "THE PURSUIT OF PROGRESS". Industry Magazine. Retrieved 2025-05-15.
  3. 1 2 "ENGAGEMENTS; Michael Stifelman and Jill Zimmerman". The New York Times. 1993-07-18. ISSN   0362-4331 . Retrieved 2025-05-15.
  4. Chan, Sewell (2007-04-05). "The Question of Circumcision and H.I.V." archive.nytimes.com. Retrieved 2025-05-15.
  5. lostinnj (2023-11-09). "Michael Stifelman | Robotic Surgery | Podcast Interview". LOST IN JERSEY. Retrieved 2025-05-15.
  6. VIVUS, Inc. (2012-09-14). "A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Study of the Safety and Efficacy of Avanafil in the Treatment of Erectile Dysfunction Following Bilateral Nerve-Sparing Radical Prostatectomy".{{cite journal}}: Cite journal requires |journal= (help)
  7. Argos Therapeutics (2018-06-13). "An International Phase 3 Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)".{{cite journal}}: Cite journal requires |journal= (help)
  8. SurgiQuest, Inc. (2016-06-02). "A Physician Preference Study of the Use of SurgiQuest AirSeal vs. Conventional Insufflation Systems for the Management of Pneumoperitoneum in Robotic Partial Nephrectomy ".{{cite journal}}: Cite journal requires |journal= (help)
  9. Hackensack Meridian Health (2020-10-15). "Quantification and Purification of Circulating Prostasomes as Diagnostic Tool for Prostate Cancer Detection". Uppsala University, Sweden (Department of Immunology, Genetics and Pathology).{{cite journal}}: Cite journal requires |journal= (help)
  10. 1 2 "Hackensack University Medical Center Urologists Offer Pioneering Clinical Trial to Study Nerve Recovery after Robotic Prostatectomy for Prostate Cancer". OncLive. 2020-10-12. Retrieved 2025-06-12.
  11. "Hackensack University Medical Center Urologists Offer Pioneering Clinical Trial to Study Nerve Recovery after Robotic Prostatectomy for Prostate Cancer | Hackensack Meridian Health". www.hackensackmeridianhealth.org. Retrieved 2025-06-12.
  12. Lepor, Herbert (2003). "Surgical, Pharmacological, and Technological Advances in Adult and Pediatric Urology-State of the Art: Highlights of the 8th Annual NYU Department of Urology Post-Graduate Course December 6-8, 2001, New York, NY". Reviews in Urology. 5 (1): 29–39. ISSN   1523-6161. PMC   1472991 . PMID   16985615.
  13. "Urology Research". Hackensack University Medical Center. Retrieved 2021-07-16.
  14. hcp1dev. "Health Concepts Partners | Just another WordPress site". HCP1. Retrieved 2021-07-01.{{cite web}}: CS1 maint: numeric names: authors list (link)
  15. "8 MHZ TQI Doppler System". Vascular Technology, Incorporated (VTI). Retrieved 2021-07-01.
  16. "Institute for Surgical Excellence". Institute for Surgical Excellence. Retrieved 2021-07-01.