John Theurer Cancer Center | |
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Geography | |
Location | 92 2nd Street, Hackensack, New Jersey, United States |
Organization | |
Funding | Non-profit hospital |
Type | Cancer treatment |
Affiliated university | Hackensack University Medical Center Georgetown Lombardi Comprehensive Cancer Center Memorial Sloan Kettering Cancer Center |
Network | Hackensack Meridian Health |
Links | |
Lists | Hospitals in the United States |
John Theurer Cancer Center (JTCC) at the Hackensack University Medical Center (HUMC), and part of the Hackensack Meridian Health (HMH), specializes in oncology services and treatments. [1] It is known for being the first site approved to use cell-based gene therapy to treat patients with certain types of large B-cell lymphoma who have not responded or relapsed after at least two other kinds of treatment; it initiated the first CAR T-cell therapy clinical trials and is a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center. Other areas of concentration include bone marrow transplants, stem cell transplantation, lymphoma, leukemia, multiple myeloma, neuro-oncology, cutaneous malignancy, gastrointestinal, geriatric, head and neck, thoracic, urologic, breast, and gynecologic. [2] As of 2023, Andre Goy is chair and Chief Physician Officer. [3] [4] [5]
In 2019, JTCC received approval from the National Cancer Institute (NCI) as a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center. [6] The partnership focuses on advancing research and treatment in breast cancer, cancer prevention and control, experimental therapeutics and molecular oncology. [7] [8] [9] The Georgetown Lombardi Comprehensive Center is designated by the National Cancer Institute as a leader in cancer treatment. [10]
JTCC is part of Hackensack University Medical Center. HUMC and part of the Hackensack Meridian Health network, which includes Joseph M. Sanzari Children's Hospital, the Cancer Center, a branch of The Betty Torricelli Institute for Breast Care, Ocean Medical Center, Pascack Valley Medical Center, and the Riverview Medical Center. [11] [12] [13]
In 2022, JTCC expanded its program to Hackensack Meridian Jersey Shore University Medical Center's HOPE Tower, providing access to specialized cancer services and access to clinical trials. [14]
JTCC has a partnership with Memorial Sloan Kettering Cancer Center (MSK) to provide cancer care and develop joint standards of care through the oversight of a governing board composed of members from both MSK and HMH. [15]
In 2021, JTCC entered into a clinical affiliation with Regional Cancer Care Associates (RCCA) to open a practice called Toms River Regional Cancer Center in Toms River, NJ. The center provides comprehensive medical and surgical oncology/hematology consultative services by community-based, regional, and national specialists for various types and stages of cancer and serious blood disorders. [13]
In 2022, JTCC entered into a clinical affiliation with St. Joseph's Health to provide expanded cancer care services to the residents of Wayne, Paterson, and Totowa.
In 2011, JTCC at HUMC opened a $130-million, 155,000-sq. ft. facility. [1] The JTCC pavilion was built with a green roof, providing patients and visitors with a relaxing environment [16] and doubling as exterior insulation—greatly reducing heat gain and loss. [17] This reduces energy use for heating and cooling as well as harmful emissions. [18]
Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. Other symptoms may include bone pain, chest pain, or itchiness. Some forms are slow-growing while others are fast-growing. Unlike Hodgkin lymphoma, which spreads contiguously, NHL is largely a systemic illness.
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes. The name typically refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night.
The University of Texas MD Anderson Cancer Center is a comprehensive cancer center in Houston, Texas. It is the largest cancer center in the world and one of the original three NCI-designated comprehensive cancer centers in the country. It is both a degree-granting academic institution and a cancer treatment and research center located within Texas Medical Center (TMC), Houston, the largest medical center and life sciences destination in the world. MD Anderson Cancer Center has consistently ranked #1 among the best hospitals for cancer care and research in the U.S. and worldwide, and it has held the #1 position 20 times in the last 23 years in U.S. News & World Report's Best Hospitals rankings for cancer care. As of 2023, MD Anderson Cancer Center is home to the highest number of cancer clinical trials in the world and has received more NCI-funded projects than any other U.S. institute. In 2024, Newsweek placed MD Anderson at #1 in their annual list of the World's Best Specialized Hospitals in oncology.
Pralatrexate, sold under the brand name Folotyn, is a medication used for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL).
Moffitt Cancer Center & Research Institute is a nonprofit cancer treatment and research center located in Tampa, Florida. Established in 1981 by the Florida Legislature, the hospital opened in October 1986 on the University of South Florida's campus. Moffitt is one of two National Cancer Institute-designated Comprehensive Cancer Centers based in Florida. In 2021, U.S. News & World Report ranked Moffitt Cancer Center as a top 30 cancer hospital in the United States.
The European Organisation for Research and Treatment of Cancer (EORTC) is a unique pan-European non-profit clinical cancer research organisation established in 1962 operating as an international association under Belgium law. It develops, conducts, coordinates and stimulates high-quality translational and clinical trial research to improve the survival and quality of life of cancer patients. This is achieved through the development of new drugs and other innovative approaches, and the testing of more effective therapeutic strategies, using currently approved drugs, surgery and/or radiotherapy in clinical trials conducted under the auspices of a vast network of clinical cancer researchers supported by 220 staff members based in Brussels. The EORTC has the expertise to conduct large and complex trials especially specific populations such as the older patient and rare tumours.
Hackensack University Medical Center (HUMC) is a 950-bed non-profit, research and teaching hospital providing tertiary and healthcare needs located seven miles (11 km) west of New York City, in Hackensack, Bergen County, New Jersey, United States. As of 2019, it ranks as the second-largest hospital in New Jersey and No. 59 in the US. HUMC is the largest hospital in the Hackensack Meridian Health Health System. It is affiliated with the New Jersey Medical School of Rutgers University and Hackensack Meridian School of Medicine. The medical center was founded in 1888 as Bergen County's first hospital, with 12 beds. The hospital is an ACS verified level 1 trauma center, one of five in the state. In 2021 it was given a grade A by the Leapfrog patient safety organization.
The Society for Immunotherapy of Cancer (SITC), previously known as the International Society for Biological Therapy of Cancer (iSBTc), is a professional society of scientists, academicians, researchers, clinicians, government representatives, and industry leaders from around the world dedicated to improving outcomes in patients with cancer by advancing the science and application of cancer immunotherapy. Currently, SITC has more than 2,400 members, representing 22 medical specialties from 42 countries around the world, who are engaged in the research and treatment of cancer.
Pascack Valley Medical Center formerly known as Hackensack University Medical Center at Pascack Valley is a full-service boutique hospital located in Westwood, New Jersey, at the site of the former Pascack Valley Hospital. Owned 35% by Hackensack University Medical Center (HackensackUMC) and 65% by Ardent Health Services, HackensackUMC at Pascack Valley serves the Pascack Valley and Northern Valley communities in northern Bergen County. In 2021 it was given a grade A by the Leapfrog patient safety organization.
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, and PARP inhibitors such as olaparib. Other therapies include hyperthermia, immunotherapy, photodynamic therapy, and stem-cell therapy. Most commonly cancer treatment involves a series of separate therapies such as chemotherapy before surgery. Angiogenesis inhibitors are sometimes used to enhance the effects of immunotherapies.
Mogamulizumab, sold under the brand name Poteligeo, is a humanized, afucosylated monoclonal antibody targeting CC chemokine receptor type 4 (CCR4). It is given by injection into a vein.
Uganda Cancer Institute (UCI) is a public, specialized, tertiary care medical facility owned by the Uganda Ministry of Health. It is designated as East Africa's Centre of Excellence in Oncology. In collaboration with Makerere University College of Health Sciences, UCI plans to start offering master's degrees, doctoral programs and post-doctoral fellowships in oncology care.
Elaine Sarkin Jaffe is a senior National Cancer Institute (NCI) investigator at the National Institutes of Health (NIH) most well known for her contribution to hematopathology. She completed her medical education at Cornell University and the University of Pennsylvania, receiving her M.D. degree from University of Pennsylvania in 1969. After an internship at Georgetown University she joined NCI as a resident in anatomic pathology, and has been a senior investigator since 1974, focusing on the classification and definition of lymphomas. Jaffe's early work helped to provide a deeper understanding of the origin of lymphomas, especially follicular lymphoma. Her team notably elucidated the difference between T cell and B cell lymphomas.
Seattle Cancer Care Alliance (SCCA) is a cancer treatment and research center in Seattle, Washington. Established in 1998, this nonprofit provides clinical oncology care for patients treated at its three partner organizations: Fred Hutchinson Cancer Research Center, Seattle Children's and UW Medicine. Together, these four institutions form the Fred Hutch/University of Washington Cancer Consortium.
Hackensack Meridian School of Medicine (HMSOM) is a private medical school in Nutley, New Jersey. When it opened in 2015, it was the first private medical school in New Jersey to open in decades. Originally affiliated with Seton Hall University, the Hackensack Meridian School of Medicine became independent in 2020.
Lorlatinib, sold under the brand name Lorbrena in the United States, Canada, and Japan, and Lorviqua in the European Union, is an anti-cancer medication used for the treatment of non-small cell lung cancer. It is an orally administered inhibitor of anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (ROS1), two enzymes that play a role in the development of cancer. It was developed by Pfizer.
Andrew Louis Pecora is an American hematologist and oncologist involved in research on the use of stem cells and oncolytic viruses to treat diseases, including cancer. He is the CEO of Outcomes Matter Innovations. As of 2020, he is on the Board of Directors Celularity, Inc. (since 2017) and founder and Executive Chairman, COTA, Inc.. Previously, he was chief innovations officer, professor and vice president of cancer services at the John Theurer Cancer Center, part of the Hackensack University Medical Center. He is a professor of medicine and oncology at Georgetown University.
Axicabtagene ciloleucel, sold under the brand name Yescarta, is a medication used for the treatment for large B-cell lymphoma that has failed conventional treatment. T cells are removed from a person with lymphoma and genetically engineered to produce a specific T-cell receptor. The resulting chimeric antigen receptor T cells (CAR-Ts) that react to the cancer are then given back to the person to populate the bone marrow. Axicabtagene treatment carries a risk for cytokine release syndrome (CRS) and neurological toxicities.
Loncastuximab tesirine, sold under the brand name Zynlonta, is a monoclonal antibody conjugate medication used to treat large B-cell lymphoma and high-grade B-cell lymphoma. It is an antibody-drug conjugate (ADC) composed of a humanized antibody targeting the protein CD19.
The Georgetown Lombardi Comprehensive Cancer Center is a cancer center located on the medical campus of Georgetown University in Washington, DC. It is one of four components of the Georgetown University Medical Center and is affiliated with MedStar Georgetown University Hospital. Additionally, it partners with MedStar Health for regional patient care. It is named in honor of Vince Lombardi, who was treated for cancer at Georgetown University Hospital.